Browse our anti-Cullin 3 (CUL3) Antibodies

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anti-Cullin 3 Antibodies (CUL3)
On are 96 Cullin 3 (CUL3) Antibodies from 23 different suppliers available. Additionally we are shipping Cullin 3 Proteins (6) and many more products for this protein. A total of 107 Cullin 3 products are currently listed.
AI467304, ATCUL3, ATCUL3A, AW146203, CUL-3, CUL-3-A, CUL-3-B, CUL3, CUL3A, cul3b, Cullin-3, Cullin-3-A, Cullin-3-B, cullin 3, cullin 3A, mKIAA0617, PHA2E, T24P13.25, wu:fc37e01
list all antibodies Gene Name GeneID UniProt
CUL3 8452 Q13618
CUL3 26554 Q9JLV5
CUL3 301555  

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anti-Human Cullin 3 Antibodies:

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Top referenced anti-Cullin 3 Antibodies

  1. Human Polyclonal Cullin 3 Primary Antibody for ICC, IF - ABIN188779 : Li, Ao, Fu, Lee, Xu, Lonard, OMalley: Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. in Oncogene 2011 (PubMed)
    Show all 2 references for 188779

  2. Chicken Monoclonal Cullin 3 Primary Antibody for IF, WB - ABIN968679 : Hori, Osaka, Chiba, Miyamoto, Okabayashi, Shimbara, Kato, Tanaka: Covalent modification of all members of human cullin family proteins by NEDD8. in Oncogene 2000 (PubMed)
    Show all 2 references for 968679

  3. Human Polyclonal Cullin 3 Primary Antibody for IP, WB - ABIN233772 : Shiraishi, Zhou, Aoki, Sato, Chiba, Tanaka, Yoshida, Nabeshima, Nabeshima, Tamura: TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation. in The Journal of biological chemistry 2007 (PubMed)

  4. Human Polyclonal Cullin 3 Primary Antibody for ICC, IF - ABIN188778 : White, Sowa, Tan, Jeudy, Hayes, Santha, Münger, Harper, Howley: Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  5. Human Polyclonal Cullin 3 Primary Antibody for IF (p), IHC (p) - ABIN705296 : Su, Zhang, Song, Shi, Fu, Xia, Bai, Hu, Xu, Song, Song: Tetrachlorobenzoquinone activates nrf2 signaling by keap1 cross-linking and ubiquitin translocation but not keap1-cullin3 complex dissociation. in Chemical research in toxicology 2015 (PubMed)

More Antibodies against Cullin 3 Interaction Partners

Arabidopsis thaliana Cullin 3 (CUL3) interaction partners

  1. Data show that CUL3 and BPM proteins assemble in planta with WRI1.

  2. The plasma membrane-associated phototropic receptor phot1 is ubiquitinated in response to blue light activation. Ubiquitination of phot1 is dependent upon both the phot1-interacting proteins NPH3 and CUL3.

  3. AtCUL3a and AtCUL3b can assemble in Arabidopsis with BTB/POZ-MATH and AtRBX1 proteins to form functional E3 ligases. [AtCUL3a]

  4. CUL3A is ubiquitously expressed in plants and is able to interact with the ring-finger protein (show TRIM31 Antibodies) RBX1 (show RBX1 Antibodies). [CUL3A]

  5. Arabidopsis CUL3A gene is essential for normal embryogenesis.

  6. work highlights that CUL3 is essential for the normal division and organisation of the root stem cell niche and columella root cap cells

  7. CUL3a and CUL3b are essential for plant development [CUL3a]

Human Cullin 3 (CUL3) interaction partners

  1. p97 (show EIF4G2 Antibodies) negatively regulates NRF2 (show GABPA Antibodies) through the canonical pathway by extracting ubiquitylated NRF2 (show GABPA Antibodies) from the KEAP1 (show KEAP1 Antibodies)-CUL3 E3 complex.

  2. CUL3 interacts with ACLY (show ACLY Antibodies) through its adaptor protein, KLHL25 (Kelch-like family member 25), to ubiquitinate and degrade ACLY (show ACLY Antibodies) in cells

  3. this work identifies both calcium and CUL3 co-adaptors as important regulators of ubiquitylation events that control human development.

  4. Together, the data indicate that a CUL3-SPOPL (show SPOPL Antibodies) E3 ubiquitin ligase (show MUL1 Antibodies) complex regulates endocytic trafficking and formation of multivesicular bodies by ubiquitinating and degrading EPS15 (show EPS15 Antibodies) at endosomes.

  5. Data show that Cullin3 exerts its function through promoting breast-cancer metastasis suppressor 1 (BRMS1 (show BRMS1 Antibodies)) protein degradation, which was associated with epithelial-mesenchymal transition (EMT (show ITK Antibodies)), migration and invasion.

  6. CUL3 acts as a tumor suppressor by regulating oxidative stress

  7. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding.

  8. Study identifies a key role of Cul3-KLHL20 (show KLHL20 Antibodies) in autophagy termination by controlling autophagy-dependent turnover of ULK1 (show ULK1 Antibodies) and VPS34 (show PIK3C3 Antibodies) complex subunits and reveals the pathophysiological functions of this autophagy termination mechanism.

  9. Data show that the differentiation of LiSa-2 preadipocytes is associated with an increase of cullin-associated and neddylation-dissociated 1 (CAND1 (show CAND1 Antibodies)), COP9 (show COPS8 Antibodies) signalosome (CSN), neddylated cullin 3 (Cul3) and the BTB protein Keap1 (show KEAP1 Antibodies).

  10. Heterodimeric CUL3 proteinubiquitylates TIAM1.CUL3 regulates TIAM1 abundance and subsequent RAC1 signaling.

Mouse (Murine) Cullin 3 (CUL3) interaction partners

  1. Myeloid deletion of Cul3 led to defective STAT3 (show STAT3 Antibodies) phosphorylation in colon macrophages, which was accompanied by exacerbated colonic inflammation and inflammation-driven tumorigenesis.

  2. Results showed that in the basal state, the amount of Keap1 (show KEAP1 Antibodies) and Cul3 proteins were maintained at higher levels than that of Nrf2 (show NFE2L2 Antibodies), and remained the same even under oxidative and electrophilic stimuli.

  3. Suggest that the hyperkalemia in knock-in mouse with the CUL3(Delta403-459) mutation is not caused by reduced ROMK (show KCNJ1 Antibodies) expression in the distal nephron.

  4. Study identifies a key role of Cul3-KLHL20 (show KLHL20 Antibodies) in autophagy termination by controlling autophagy-dependent turnover of ULK1 (show ULK1 Antibodies) and VPS34 (show PIK3C3 Antibodies) complex subunits and reveals the pathophysiological functions of this autophagy termination mechanism.

  5. These results suggest that KLHL2 (show KLHL2 Antibodies) likely plays a role in the pathogenesis of FHHt, and aggravates the phenotype caused by mutations in CUL3 and WNK4 (show WNK4 Antibodies).

  6. Hypoxia-responsive miR (show MLXIP Antibodies)-101 stimulates angiogenesis by activating the HO-1 (show HMOX1 Antibodies)/VEGF (show VEGFA Antibodies)/eNOS (show NOS3 Antibodies) axis via Cul3 targeting

  7. Mutation of cul3 protein is involved in the development of renal hypertension and chronic kidney diseases.

  8. Data show that Bcl6 (show BCL6 Antibodies) (B cell lymphoma 6)-cullin 3 complexes provide essential negative feedback regulation during both thymocyte development and T cell activation to restrain excessive T follicular helper (Tfh) responses.

  9. Knockdown of Cullin-3 or inhibition of cullin-RING ligase activity in aortic smooth muscle cells increased RhoA (show RHOA Antibodies).

  10. CUL3 deletion in mice demonstrated an essential role for CUL3 in the development of PLZF (show ZBTB16 Antibodies)- and BCL6 (show BCL6 Antibodies)-dependent lineages; distinct lineage-specific BTB-ZF transcription factors recruit CUL3 to alter the ubiquitination pattern of their associated chromatin-modifying complex

Caenorhabditis elegans (C. elegans) Cullin 3 (CUL3) interaction partners

  1. KEL-8 is a substrate receptor for Cullin 3 ubiquitin ligases that is required for the proteolysis of GLR-1 receptors and suggest a novel postmitotic role in neurons for Kelch/CUL3 ubiquitin ligases.

  2. The BTB-containing protein MEL-26 is a component required for degradation of MEI-1 (show MEI1 Antibodies) in vivo; importantly, MEL-26 specifically interacts with CUL-3 and MEI-1 (show MEI1 Antibodies) in vivo and in vitro, and displays properties of a substrate-specific adaptor

  3. the identification of a large family of BTB-domain proteins as substrate-specific adaptors for C. elegans CUL-3

  4. FIGL-1 by the CUL-3MEL-26 E3 ligase spatially restricts FIGL-1 function to mitotic cells, where it is required for correct progression through mitosis.

  5. cullin (CUL)-3 as a component of E3 ligase and KEL-8 as the substrate adaptor of RPY-1.

Cullin 3 (CUL3) Antigen Profile

Antigen Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Cullin 3 (CUL3)

  • cullin 3 (CUL3) antibody
  • cullin 3 (cul3) antibody
  • cullin 3 (cul3-a) antibody
  • cullin 3 (cul3-b) antibody
  • cullin-3 (PTRG_11586) antibody
  • Cullin-3 (CUL-3) (Smp_117580) antibody
  • cullin 3a (cul3a) antibody
  • cullin 3 (Cul3) antibody
  • Protein CUL-3 (cul-3) antibody
  • AI467304 antibody
  • ATCUL3 antibody
  • ATCUL3A antibody
  • AW146203 antibody
  • CUL-3 antibody
  • CUL-3-A antibody
  • CUL-3-B antibody
  • CUL3 antibody
  • CUL3A antibody
  • cul3b antibody
  • Cullin-3 antibody
  • Cullin-3-A antibody
  • Cullin-3-B antibody
  • cullin 3 antibody
  • cullin 3A antibody
  • mKIAA0617 antibody
  • PHA2E antibody
  • T24P13.25 antibody
  • wu:fc37e01 antibody

Protein level used designations for anti-Cullin 3 (CUL3) Antibodies

cullin-3 , cullin-3-A , cullin-3-B , Cullin-3 (CUL-3) , cullin 3 , CUL-3

100061420 Equus caballus
548729 Xenopus (Silurana) tropicalis
446487 Xenopus laevis
444103 Xenopus laevis
6349903 Pyrenophora tritici-repentis Pt-1C-BFP
8349090 Schistosoma mansoni
324655 Danio rerio
744812 Pan troglodytes
839226 Arabidopsis thaliana
8452 Homo sapiens
26554 Mus musculus
301555 Rattus norvegicus
424804 Gallus gallus
477392 Canis lupus familiaris
534325 Bos taurus
178547 Caenorhabditis elegans
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