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Human Caveolin-1 ELISA Kit for Sandwich ELISA - ABIN414704
Gumulec, Sochor, Hlavna, Sztalmachova, Krizkova, Babula, Hrabec, Rovny, Adam, Eckschlager, Kizek, Masarik: Caveolin-1 as a potential high-risk prostate cancer biomarker. in Oncology reports 2012
Show all 7 Pubmed References
Mouse (Murine) Caveolin-1 ELISA Kit for Sandwich ELISA - ABIN1114029
Xu, Nan, Bai, Shen, Hu: Caveolin-1 as a biomarker to predict therapeutic effect of low-frequency ultrasound combined with SonoVue on prostate cancer in nude mice model. in Cancer biomarkers : section A of Disease markers 2014
Dog (Canine) Caveolin-1 ELISA Kit for Sandwich ELISA - ABIN414203
Bach, Zhang, Miranda-Bedate, Verdonschot, Bergknut, Creemers, Ito, Sakai, Chan, Meij, Tryfonidou: Increased caveolin-1 in intervertebral disc degeneration facilitates repair. in Arthritis research & therapy 2016
These results point to intestinal epithelial cell CAV1 as a potential therapeutic target to lower circulating free fatty acids and LDL cholesterol.
Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.
The development of transgenic zebrafish lines expressing CLTA (show CLTA ELISA Kits) fused to dsRed and CAV1 fused to GFP is reported.
maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin (show CTNNB1 ELISA Kits)
These results support important and previously unanticipated roles for the Caveolin-1 isoforms in vertebrate organogenesis.
interactions of cav1 at lipid-exposed domains regulate the partition of the receptor into membrane raft microdomains
Caveolin-1 enhances internalization and degradation of ABCA1 (show ABCA1 ELISA Kits) by its association with ABCA1 (show ABCA1 ELISA Kits)
cav-1 knockout mice exhibited higher levels of homeostatic model assessment of insulin resista (show INS ELISA Kits)nce, cholesterol, and resistin and lower ratios of high- to low-density lipoprotein. cav-1 knockout mice displayed hypertriglyc (show INS ELISA Kits)eridemia and higher mRNA (show RETN ELISA Kits) levels for resistin, retinol binding protein 4, NADPH oxidase 4, and aldose reductase in liver and/or fat tissues.
we conclude that Cav-1 could play a critical role in preventing nitrative stress-induced liver damage during hepatic ischemia-reperfusion injury
Cav-1 deficiency induces premature senescence via mitochondrial dysfunction and SIRT1 (show SIRT1 ELISA Kits) inactivation.
Data show that phosphorylation of caveolin-1 on Tyr (show TYR ELISA Kits)(14) in microglia induced the internalization of sodium-vitamin C cotransporter 2 (SVCT2 (show SLC23A2 ELISA Kits)).
caveolin-1 maintains mitochondrial integrity and function when cells are challenged with free radicals by promoting the mitochondrial localization of m-AAA (show AAAS ELISA Kits) protease and its quality control functions.
the PRNP octapeptide repeat domain was necessary to promote exosome secretion and to impair the formation of the CAV1-dependent ATG12-ATG5 cytoplasmic complex that drives autophagosome formation.
results identify a role for Cav1 in membrane organization and beta2 integrin function in primary CD8 (show CD8A ELISA Kits) T cells.
we have identified Cav1 as a regulator of the nanoscale organization of IgM-BCRs and IgD-BCRs in the plasma membrane of B cells.
Disruption of Ankyrin B (show ANK2 ELISA Kits) and Caveolin-1 Interaction Sites Alters Na(+),K(+)-ATPase (show ATP1A1 ELISA Kits) Membrane Diffusion
These results suggest that Cav-1 may be a predictor of the poor efficacy of EGFR (show EGFR ELISA Kits)-TKIs treatment in lung adenocarcinoma with EGFR (show EGFR ELISA Kits) mutations.
Studied effect of Aliskiren on interleukin-6 (show IL6 ELISA Kits), endothelial nitric oxide synthase (show NOS3 ELISA Kits) and caveolin-1 in human aortic endothelial cells. Findings suggest that aliskiren reverses the effects of IL-6 (show IL6 ELISA Kits) on eNOS (show NOS3 ELISA Kits) and caveolin-1 thru increase in eNOS (show NOS3 ELISA Kits) phosphorylation and nitric oxide production, decrease caveolin-1 phosphorylation, and decrease the interaction between eNOS (show NOS3 ELISA Kits) and caveolin-1.
miR (show MLXIP ELISA Kits)-192 is downregulated in rheumatoid arthritis (RA)synovial tissues and restoration of its expression elicits growth-suppressive effects on RA-FLSs by targeting CAV1. The miR (show MLXIP ELISA Kits)-192/CAV1 pathway may represent a novel target for prevention and treatment of RA.
At the CAV1 gene polymorphism rs926198, minor allele carriers displayed higher odds of insulin (show INS ELISA Kits) resistance and low high-density lipoprotein. Aldosterone levels correlated with higher homeostatic model assessment of insulin (show INS ELISA Kits) resistance and resistin (show RETN ELISA Kits) and lower high-density lipoprotein only in minor allele carriers.
Our findings highlight the importance of Cav-1 in hematogenous metastasis, and provide new insights into the underlying mechanisms of mechanotransduction induced by low shear stress
Deregulated expression of miR-107 inhibits metastasis of pancreatic ductal adenocarcinoma through inhibition PI3K/Akt signaling via caveolin-1 and PTEN.
Findings suggest caveolin-1 (Cav-1) as a predictive biomarker for the response to nab-paclitaxel and other albumin (show ALB ELISA Kits)-based cancer therapeutic drugs.
Caveolin-1 (Cav-1) is a scaffolding protein and has been reported to interact with several signaling proteins, including epidermal growth factor receptor (show EGFR ELISA Kits).
Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer
transcription factor Sp1 (show SP1 ELISA Kits) interacts with nucleotides -123/-114, indicating that Sp1 (show SP1 ELISA Kits) could play a key role in the transcriptional regulation of pig CAV-1
Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.
The plasma membrane Na/K-ATPase (show ATP1A1 ELISA Kits)-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP ELISA Kits) pathway.
The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF (show NGFB ELISA Kits)/TrkA (show NTRK1 ELISA Kits) signaling.
Cav-1 might be a candidate gene for carcass traits, and might provide valuable information for understanding the mechanism of caveolae signaling in fat deposition by using the animal model of pig
Caveolin-1 expression ameliorates nephrotic damage in a rabbit model of cholesterol-induced hypercholesterolemia.
8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.
Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 ELISA Kits) signaling
Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS (show NOS3 ELISA Kits)) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).
these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS (show NOS3 ELISA Kits).
Study identifies a critical role of caveolin-1 in the regulation of eNOS (show NOS3 ELISA Kits) uncoupling via a biopterin-dependent mechanism.
Data indicate that caveolin-1 expression is required for insulin (show INS ELISA Kits) uptake by aortic endothelial cells.
caveolin-1 is not required for the targeting of signaling molecules to caveolae/lipid rafts
integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk (show CSK ELISA Kits) association at integrin sites, where it plays a role in downstream, shear-stimulated myelin light chain diphosphorylation.
importance of CAV1 amino acids 89-95 and particularly F92 in mediating eNOS (show NOS3 ELISA Kits) inhibition by AP-Cav and Cav-1
When endothelial cells were exposed to shear stress, caveolin-1 was transiently dephosphorylated.
caveolin-1 tyrosine 14 phosphorylation has a role in cell adhesion and migration
results suggest that cell division control protein 42(CDC42 (show CDC42 ELISA Kits)) activation is favored by the disruption of the caveolin-1-CDC42 (show CDC42 ELISA Kits) interaction, allowing for its participation in the regulation of capacitation and the acrosome reaction
The distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization.
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
, caveolin 1
, caveolin, caveolae protein 1
, caveolin, caveolae protein, 22 kDa
, caveolin caveolae protein 22 kDa
, vesicular integral-membrane protein VIP21
, cell growth-inhibiting protein 32
, testis derived transcript