Browse our Caveolin-1 Proteins (CAV1)

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Caveolin 1, Caveolae Protein, 22kDa Proteins (CAV1)
On are 38 Caveolin 1, Caveolae Protein, 22kDa (CAV1) Proteins from 7 different suppliers available. Additionally we are shipping Caveolin-1 Antibodies (324) and Caveolin-1 Kits (85) and many more products for this protein. A total of 459 Caveolin-1 products are currently listed.
BSCL3, Cav, cav-1, CAV1, cav1a, cav1b, Caveolin-1, caveolin 1, CGL3, fc07c04, MSTP085, PPH3, VIP21, wu:fc07c04
list all proteins Gene Name GeneID UniProt
CAV1 12389 P49817
CAV1 25404  
CAV1 857 Q03135

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Caveolin-1 Proteins (CAV1) by Origin

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Top referenced Caveolin-1 Proteins

  1. Human Caveolin-1 Protein expressed in Wheat germ - ABIN1348146 : Kastelijn, van Moorsel, Kazemier, Roothaan, Ruven, Kwakkel-van Erp, van de Graaf, Zanen, van Kessel, Grutters: A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation. in Fibrogenesis & tissue repair 2011 (PubMed)
    Show all 4 references for 1348146

More Proteins for Caveolin-1 Interaction Partners

Zebrafish Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.

  2. The development of transgenic zebrafish lines expressing CLTA (show CLTA Proteins) fused to dsRed and CAV1 fused to GFP is reported.

  3. maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin (show CTNNB1 Proteins)

  4. These results support important and previously unanticipated roles for the Caveolin-1 isoforms in vertebrate organogenesis.

Xenopus laevis Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. interactions of cav1 at lipid-exposed domains regulate the partition of the receptor into membrane raft microdomains

Mouse (Murine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. results identify a role for Cav1 in membrane organization and beta2 integrin function in primary CD8 (show CD8A Proteins) T cells.

  2. we have identified Cav1 as a regulator of the nanoscale organization of IgM-BCRs and IgD-BCRs in the plasma membrane of B cells.

  3. CAV1 serves as an important protective factor in the development of NAFLD by modulating lipid metabolism gene expression

  4. The findings of this study suggested an important role by which neuron-targeted Cav-1 regulates DISC1 (show DISC1 Proteins) neurobiology with implications for synaptic plasticity.

  5. CAV1 is an anti-lithogenic factor and that the CAV1(-/-) mice may offer a convenient CGD (show CYBB Proteins) model to develop therapeutic interventions for this disease

  6. these findings indicated that the downregulation of GATA-6 (show GATA6 Proteins) effectively inhibited airway inflammation and reversed airway remodeling via Cav-1

  7. Cav1, and presumably caveolae, in vascular smooth muscle and the endothelium plays a critical role in vascular remodeling and inflammation independent of blood pressure or cardiac hypertrophy regulation.

  8. Neuron-targeted overexpression of caveolin-1 in the adult and aged hippocampus enhances functional membrane/lipid rafts with corresponding roles in cell signaling and protein trafficking.

  9. Loss of cav-1 resulted in increased ECM (show MMRN1 Proteins) protein expression in murine mammary glands and abnormal ductal architecture.

  10. Cav-1 depletion, oxidative stress-mediated reduction in BMPRII (show BMPR2 Proteins) expression, and enhanced TGF-beta (show TGFB1 Proteins)-driven SMAD-2 (show SMAD2 Proteins)/3 signaling promote pulmonary vascular remodeling in inflamed lungs.

Human Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. These results demonstrate the critical role of the final 20 amino acids of caveolin-1 in modulating fibroblast proliferation by dampening Smad (show SMAD1 Proteins) signaling and suggest that augmented Smad (show SMAD1 Proteins) signaling and fibroblast hyperproliferation are contributing factors in the pathogenesis of PAH in patients with caveolin-1 c.474delA mutation.

  2. Results indicate that Moyamoya disease is related to caveolin-1 but not to endothelial dysfunction or dysregulation of circulating cytokines, and suggest that Moyamoya disease is a disorder of caveolae which involves regulation of endothelial vesicular trafficking and signal transduction.

  3. Cav-1 expression and low shear stress promote breast cancer cells motility and adhesion and triggered cells to rapidly generate new lamellipodia.

  4. we demonstrated that the novel molecule of cell migration and invasion, caveolin-1, has direct interaction with NDRG1 in human colorectal cancer cells

  5. Data suggest that the predominant plasmalemmal anionic lipid phosphatidylserine is essential for proper caveolin/cavin (show PTRF Proteins) clustering, caveola formation, and caveola dynamics; membrane scrambling (by using other phospholipids) can perturb caveolar stability; these studies involved caveolin-1 and cavin-1 (show PTRF Proteins) as models of caveolin/cavin (show PTRF Proteins) clustering.

  6. EGFR (show EGFR Proteins) upregulation was detected in the group of thyroid cancer patients with malignant diagnosis, no caveolin-1 expression, and wild-type BRAF (show BRAF Proteins).

  7. This study determined the genetic polymorphisms of the eNOS (show NOS3 Proteins) (Glu298Asp) and Cav-1 (G14713A and T29107A) genes in association with susceptibility risk in patients who had suffered from a large artery atherosclerotic stroke. It demonstrated that the eNOS (show NOS3 Proteins) Glu298Asp in combination with 14713A/29107A at the CAV1 locus was associated with a significant risk of an large artery atherosclerotic stroke.

  8. gestational diabetes-induced macrosomias have more severe inhibition of Cav-1 expression in placenta. Cav-1 is associated with placental glucose and fatty acid transport via the induction of AMPK (show PRKAA1 Proteins) signaling pathway and the reduction of GLUT1 (show SLC2A1 Proteins) signaling pathway to reverse gestational diabetes-induced macrosomia.

  9. The CAV1 rs4730751 CC genotype is associated with lower arterial stiffness in patients with early and late stage non-dialysis chronic kidney disease.

  10. DNA methylation (show HELLS Proteins) profiling identifies PTRF/Cavin-1 (show PTRF Proteins) as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1, which PTRF (show PTRF Proteins), disrupts the MDM2 (show MDM2 Proteins)/p53 (show TP53 Proteins) complex, leading to apoptosis.

Pig (Porcine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer

  2. transcription factor Sp1 (show SP1 Proteins) interacts with nucleotides -123/-114, indicating that Sp1 (show SP1 Proteins) could play a key role in the transcriptional regulation of pig CAV-1

  3. Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.

  4. The plasma membrane Na/K-ATPase (show ATP1A1 Proteins)-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP Proteins) pathway.

  5. The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF (show NGFB Proteins)/TrkA (show NTRK1 Proteins) signaling.

  6. Cav-1 might be a candidate gene for carcass traits, and might provide valuable information for understanding the mechanism of caveolae signaling in fat deposition by using the animal model of pig

Rabbit Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 expression ameliorates nephrotic damage in a rabbit model of cholesterol-induced hypercholesterolemia.

  2. 8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.

Cow (Bovine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 Proteins) signaling

  2. Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS (show NOS3 Proteins)) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).

  3. these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS (show NOS3 Proteins).

  4. Study identifies a critical role of caveolin-1 in the regulation of eNOS (show NOS3 Proteins) uncoupling via a biopterin-dependent mechanism.

  5. Data indicate that caveolin-1 expression is required for insulin (show INS Proteins) uptake by aortic endothelial cells.

  6. caveolin-1 is not required for the targeting of signaling molecules to caveolae/lipid rafts

  7. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk (show CSK Proteins) association at integrin sites, where it plays a role in downstream, shear-stimulated myelin light chain diphosphorylation.

  8. importance of CAV1 amino acids 89-95 and particularly F92 in mediating eNOS (show NOS3 Proteins) inhibition by AP-Cav and Cav-1

  9. When endothelial cells were exposed to shear stress, caveolin-1 was transiently dephosphorylated.

  10. caveolin-1 tyrosine 14 phosphorylation has a role in cell adhesion and migration

Guinea Pig Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. results suggest that cell division control protein 42(CDC42 (show CDC42 Proteins)) activation is favored by the disruption of the caveolin-1-CDC42 (show CDC42 Proteins) interaction, allowing for its participation in the regulation of capacitation and the acrosome reaction

Caenorhabditis elegans (C. elegans) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. The distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization.

Caveolin-1 (CAV1) Protein Profile

Protein Summary

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Alternative names and synonyms associated with Caveolin-1 (CAV1)

  • caveolin 1 (cav1)
  • caveolin 1, caveolae protein, 22kDa (cav1-b)
  • caveolin 1, caveolae protein, 22kDa (cav1-a)
  • caveolin 1, caveolae protein, 22kDa (cav1)
  • caveolin 1, caveolae protein, 22kDa (CAV1)
  • caveolin 1 (CAV1)
  • caveolin 1, caveolae protein (Cav1)
  • caveolin 1, caveolae protein, 22kDa (Cav1)
  • Protein CAV-1 (cav-1)
  • BSCL3 protein
  • Cav protein
  • cav-1 protein
  • CAV1 protein
  • cav1a protein
  • cav1b protein
  • Caveolin-1 protein
  • caveolin 1 protein
  • CGL3 protein
  • fc07c04 protein
  • MSTP085 protein
  • PPH3 protein
  • VIP21 protein
  • wu:fc07c04 protein

Protein level used designations for CAV1

caveolin-1 , caveolin 1 , caveolin, caveolae protein 1 , caveolin, caveolae protein, 22 kDa , caveolin caveolae protein 22 kDa , vesicular integral-membrane protein VIP21 , cell growth-inhibiting protein 32 , testis derived transcript

323695 Danio rerio
398392 Xenopus laevis
399006 Xenopus laevis
548467 Xenopus (Silurana) tropicalis
100126666 Papio anubis
100137140 Ornithorhynchus anatinus
100137154 Takifugu rubripes
12389 Mus musculus
25404 Rattus norvegicus
403980 Canis lupus familiaris
857 Homo sapiens
404693 Sus scrofa
100008837 Oryctolagus cuniculus
281040 Bos taurus
704449 Macaca mulatta
100055975 Equus caballus
373996 Gallus gallus
100718512 Cavia porcellus
493668 Felis catus
445468 Ovis aries
100860749 Capra hircus
100137027 Pongo abelii
463670 Pan troglodytes
100407940 Callithrix jacchus
177815 Caenorhabditis elegans
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