You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our BAD Proteins (BAD)

Full name:
BCL2-Associated Agonist of Cell Death Proteins (BAD)
On www.antibodies-online.com are 9 BCL2-Associated Agonist of Cell Death (BAD) Proteins from 6 different suppliers available. Additionally we are shipping BAD Antibodies (971) and BAD Kits (50) and many more products for this protein. A total of 1106 BAD products are currently listed.
Synonyms:
AI325008, BAD, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04
list all proteins Gene Name GeneID UniProt
BAD 572 Q92934
BAD 12015 Q61337
BAD 64639 O35147

Show all synonyms

BAD Proteins (BAD) by Origin

Select your origin of interest

More Proteins for BAD Interaction Partners

Zebrafish BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad functions as an essential sensitizer and Puma (show BBC3 Proteins) as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

  2. Stage-specific expression of TNFalpha (show TNF Proteins) regulates bad/bid (show BID Proteins)-mediated apoptosis and RIP1 (show RALBP1 Proteins)/ROS (show ROS1 Proteins)-mediated secondary necrosis in Birnavirus-infected fish cells.

  3. Results indicate that zebrafish BH3-only (show BBC3 Proteins) proapoptotic protein (BAD) could induce apoptosis in vitro and in vivo and may have biological implications in apoptosis during zebrafish development.

Human BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bcl-xL (show BCL2L1 Proteins) is responsible for TRAIL resistance in human pancreatic cancer cells. Bcl-2 (show BCL2 Proteins) family inhibitors could represent promising reagents to sensitize human pancreatic cancers to TRAIL.

  2. This studypredict response ketogenic dietary therapies. showed that Common variants in KCNJ11 (show KCNJ11 Proteins) and BAD do not responase to ketogenic diet therapy.

  3. Bcl-xL (show BCL2L1 Proteins) binds to dual BH3-like domains in the InsP3 receptor carboxyl terminus and regulates control of cell viability.

  4. LA provoked a down regulation of two anti-apoptotic proteins, Mcl-1 (show MCL1 Proteins) and Bcl-xL (show BCL2L1 Proteins) protein and a strong induction of the BH3-only (show BBC3 Proteins) protein Bim (show BCL2L11 Proteins).

  5. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (show GABPA Proteins) and Bcl-xL (show BCL2L1 Proteins).

  6. A Novel Naphthalimide Compound Restores p53 (show TP53 Proteins) Function in Non-small Cell Lung Cancer by Reorganizing the Bak.Bcl-xl Complex and Triggering Transcriptional Regulation.

  7. These data suggest that miR (show MLXIP Proteins)-BART20-5p plays an important role in latency maintenance and tumor persistence of Epstein-Barr virus-associated gastric carcinoma by inhibiting BAD-mediated caspase-3 (show CASP3 Proteins)-dependent apoptosis.

  8. Taken together, these data indicate that the downregulation of Bad and Bim (show BCL2L11 Proteins) plays a significant role in the autophagy-induced chemoresistance of hepatocellular carcinoma cells.

  9. These data suggest that Bcl-XL binds to RyR channels via its BH4 domain, but also its BH3 domain, more specific Lys87, contributes to the interaction.

  10. Study support that mitochondrial ERb (show ESR2 Proteins) prevents cell apoptosis through its interaction with bad protein and the mitochondrial apoptotic pathway in a ligand-independent manner.

Mouse (Murine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad is dispensable for TNF (show TNF Proteins)-mediated cell death.

  2. Results indicate the downstream targets of insulin (show INS Proteins), cyclin D1 (show CCND1 Proteins), BAD, alpha-MHC (show MYH6 Proteins), and GATA-4 (show GATA4 Proteins), elucidate a molecular mechanism of insulin (show INS Proteins) in promoting cell proliferation and differentiation.

  3. our study suggests that Bad and Bmf (show BMF Proteins) co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.

  4. Results reveal that IKK (show CHUK Proteins) inhibits TNFalpha (show TNF Proteins)-induced apoptosis through two distinct but cooperative mechanisms: activation of the survival factor NF-kappaB (show NFKB1 Proteins) and inactivation of the proapoptotic BH3-only (show BBC3 Proteins) BAD protein.

  5. RNAi-mediated silencing of STAT1 (show STAT1 Proteins) in soft tissue sarcoma (STS (show STS Proteins)) cells was sufficient to increase expression of the apoptotic mediators Fas (show FAS Proteins) and Bad and to elevate the sensitivity of STS (show STS Proteins) cells to Fas (show FAS Proteins)-mediated apoptosis

  6. Tonicity-induced COX-2 expression and PGE2 synthesis in the renal medulla entails phosphorylation and inactivation of the pro-apoptotic protein Bad, thereby counteracting apoptosis in renal medullary epithelial cells.

  7. Caspase-3 (show CASP3 Proteins) is activated by the BAD-BAX (show BAX Proteins) cascade resulting in long term depression induction in the hippocampus.

  8. JNK1 (show MAPK8 Proteins) is required for erythropoietin (show EPO Proteins)-mediated cell survival through phosphorylation and inactivation of the pro-apoptotic, Bcl-2 (show BCL2 Proteins) homology domain 3 (BH3)-only (show BBC3 Proteins) Bcl-associated death protein (Bad).

  9. Bad protein cooperate with bim (show BCL2L11 Proteins) protein in certain apoptotic responses and in the suppression of g-irradiation-induced thymic lymphoma.(Bad protein)

  10. Data show that loss of Bmf (show BMF Proteins) reduced the pressure to inactivate p53 (show TP53 Proteins), whereas Bad deficiency did not, identifying Bmf (show BMF Proteins) as a novel component of the p53 (show TP53 Proteins)-independent tumor suppressor pathway triggered by c-Myc (show MYC Proteins).

Cow (Bovine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

BAD Protein Profile

Protein Summary

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

  • BCL2-antagonist of cell death b (badb)
  • BCL2-associated agonist of cell death (BAD)
  • BCL2-associated agonist of cell death (Bad)
  • AI325008 protein
  • BAD protein
  • Bbc2 protein
  • BCL2L8 protein
  • fa01b12 protein
  • wu:fa01b12 protein
  • wu:fa96d04 protein

Protein level used designations for BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter

GENE ID SPECIES
58100 Danio rerio
768269 Felis catus
780444 Ovis aries
572 Homo sapiens
12015 Mus musculus
64639 Rattus norvegicus
483763 Canis lupus familiaris
615013 Bos taurus
Selected quality suppliers for BAD Proteins (BAD)
Did you look for something else?