BAD Products
(BCL2-Associated Agonist of Cell Death (BAD))
Categories
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008].
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Featured BAD Categories
BAD Antibodies
High quality antibodies with extensive validation data.
BAD ELISA Kits
Reliable ELISA kits for a wide range of species.
BAD Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BAD Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro)
Validations
- (3)
- (1)
Cat. No.
ABIN674709
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (8)
Cat. No.
ABIN7443224
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5542486
Quantity
0.1 mg
Datasheet
Datasheet
Recommended BAD ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965132
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965131
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965127
Quantity
96 tests
Datasheet
Datasheet
Recommended BAD Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346356
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1775808
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3089977
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BAD products
: "Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562." in: Gene, Vol. 692, pp. 217-222, (2019) (PubMed).: "GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia." in: International journal of molecular medicine, Vol. 38, Issue 1, pp. 105-12, (2017) (PubMed).
: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." in: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).
: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." in: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).
: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." in: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).
: "Involvement of caspases and their upstream regulators in myocardial apoptosis in a rat model of selenium deficiency-induced dilated cardiomyopathy." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 31, pp. 85-91, (2015) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "Loss of Bad expression confers poor prognosis in non-small cell lung cancer." in: Medical oncology (Northwood, London, England), Vol. 29, Issue 3, pp. 1648-55, (2012) (PubMed).
: "ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer." in: PLoS ONE, Vol. 6, Issue 2, pp. e16916, (2011) (PubMed).
: "BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17934-44, (2011) (PubMed).
Synonyms and alternative names related to BAD
BCL2-associated agonist of cell death b (badb), BCL2 associated agonist of cell death (BAD), BCL2-associated agonist of cell death (Bad), AI325008, bad, BAD, BBC2, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04Protein level used designations for BAD
- proapoptotic BH3-only protein
- BCL2-antagonist of cell death
- BCL2-associated agonist of cell death
- BCL-X/BCL-2 binding protein
- BCL2-antagonist of cell death protein
- BCL2-binding component 6
- BCL2-binding protein
- bcl-2-binding component 6
- bcl-2-like protein 8
- bcl-XL/Bcl-2-associated death promoter
- bcl2 antagonist of cell death
- bcl2-L-8
- Bcl-associated death promoter
- bcl-xL/Bcl-2-associated death promoter
- Bcl2-antagonist of cell death
- bcl-2 associated death agonist
- bcl2-associated death promoter
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