anti-Human BCL2 antibody for Flow Cytometry

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2-like
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • LOC100224888
  • bcl2
  • LOC100359045
  • BCL-2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1060
257
212
54
28
22
18
18
5
4
4
3
2
2
2
2
Host
Mouse
578
547
19
6
2
2
2
Clonality
Monoclonal
Conjugate
This BCL2 antibody is conjugated to PE
50
50
44
38
25
24
22
16
15
14
14
14
14
14
14
14
13
13
13
7
7
7
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
839
398
388
342
335
327
235
195
171
81
40
15
14
13
12
11
9
4
3
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2853587
$ 508.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.996978 ABIN4283376 ELISA FACS ICC IF IHC IHC (p) Mouse IgG1 Log in to see 8E12 1
13.996978 ABIN4283388 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa Log in to see 8C8
13.996978 ABIN2662398 FACS PE Mouse IgG1 AA 41-54 Log in to see 100 7
13.996978 ABIN2657052 FACS Alexa Fluor 488 Mouse IgG1 AA 41-54 Log in to see 100 7
13.996978 ABIN2657117 FACS IP Alexa Fluor 647 Mouse IgG1 AA 41-54 Log in to see 100 7
13.996978 ABIN967321 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
13.996978 ABIN967322 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
13.996978 ABIN968975 ICC FACS IHC ELISA Mouse IgG1 Log in to see 8-00E-12 3
13.996978 ABIN3026595 FACS IF IHC ELISA WB Mouse IgG1, kappa AA 41-54 Log in to see 124
13.996978 ABIN3026609 FACS IF IP IHC ELISA WB Mouse IgG1, kappa Log in to see 100-D5
13.996978 ABIN3024192 FACS IF IP IHC WB Mouse IgG1, kappa AA 41-54 Log in to see 100-D5-124
13.996978 ABIN1302954 FACS ICC IHC (f) IHC (p) IP WB FITC Mouse IgG1 AA 41-54 Log in to see Bcl-2-100 4
13.996978 ABIN1105505 EIA FACS IF IHC (p) WB Mouse IgG1 Log in to see 8-00E-012
13.996978 ABIN1846239 ELISA FACS IF/ICC IHC Mouse IgG1 Log in to see
1 ABIN1105506 FACS WB Mouse IgG1 Log in to see 83-8B 2
1 ABIN781706 FACS FITC Mouse IgG1 AA 41-54 Log in to see Bcl2-100 6
1 ABIN781708 FACS PE Mouse IgG1 AA 41-54 Log in to see Bcl2-100 6
1 ABIN967312 IHC (fro) FACS IF IP WB Armenian Hamster IgG Log in to see 6C8 13
1 ABIN967311 IHC (fro) FACS IF IP WB Hamster IgG Log in to see 6C8 13
1 ABIN337080 FACS IF IHC (p) ELISA WB Mouse IgG1 AA 41-54 Log in to see

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1060), (257), (212), (54), (28), (22), (18), (18), (5), (4), (4), (3), (2), (2), (2), (2)
Host Mouse
(578), (547), (19), (6), (2), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL2 antibody is conjugated to PE
(50), (50), (44), (38), (25), (24), (22), (16), (15), (14), (14), (14), (14), (14), (14), (14), (13), (13), (13), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(839), (398), (388), (342), (335), (327), (235), (195), (171), (81), (40), (15), (14), (13), (12), (11), (9), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling References for anti-BCL2 antibody (ABIN2853587) Images
Specificity This antibody reacts with Bcl-2.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Protein A agarose
Immunogen Recombinant rat Bcl-2beta
Clone 83-8B
Isotype IgG1

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling References for anti-BCL2 antibody (ABIN2853587) Images back to top
Antigen
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background The Bcl-2 related genes can inhibit (Bcl-XL and Mcl-1) or induce (Bax, Bcl-Xs, Bag and Bad) apoptosis in several systems. Bad was identified as a Bcl-2 interacting protein using a yeast two hybrid screening and λ expression cloning. It has homology to Bcl-2 within the Bcl-2 homolog domains 1 and 2 (BH1 and BH2). In mammalian cells, Bad selectively heterodimerizes with Bcl-XL as well as Bcl-2, but not with other Bcl-2 family members (Bax, Bcl-Xs, Mcl-1 and A1). When Bad heterodimerized with Bcl-XL, it displaced Bax from Bcl-XL and promoted cell death.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Gene ID 24224
NCBI Accession NP_058689
UniProt P49950
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling References for anti-BCL2 antibody (ABIN2853587) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details References for anti-BCL2 antibody (ABIN2853587) Images back to top
Format Liquid
Buffer PBS, 0.09 % NaN3, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-BCL2 antibody (ABIN2853587)

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling Images back to top
Background publications

Gallatin, Weissman, Butcher: "A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 1, pp. 5-9, 2006

Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: "Resistance to Fas-mediated apoptosis in human lung fibroblast." in: The European respiratory journal, Vol. 20, Issue 2, pp. 359-68, 2002

Images

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling References for anti-BCL2 antibody (ABIN2853587) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (PE) (ABIN2853587) anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (PE)