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anti-Rat (Rattus) DAP Kinase 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended DAP Kinase 1 Antibody (supplied by: Log in to see )

Antigen
Death-Associated Protein Kinase 1 (DAPK1) Antibodies
  • DAPK1
  • MGC81366
  • si:ch211-66i11.1
  • wu:fj09c03
  • dapk
  • MGC83745
  • 2310039H24Rik
  • 2810425C21Rik
  • AI642003
  • D13Ucla1
  • DAP-Kinase
  • DAPK
  • death-associated protein kinase 1
  • death associated protein kinase 1
  • LOC427465
  • dapk1
  • DAPK1
  • LOC100343775
  • dapk1-b
  • RCJMB04_1b10
  • Dapk1
Epitope
AA 1360-1410
19
15
14
14
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
92
48
23
4
2
1
1
Host
Rabbit
85
7
Clonality
Polyclonal
Conjugate
This DAP Kinase 1 antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
62
45
32
15
14
12
3
2
2
2
1
1
1
Options
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Catalog No. ABIN732983
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN732992 IHC (p) WB HRP Rabbit IgG AA 1360-1410 Log in to see Polyclonal
1 ABIN2962483 IHC (p) WB Rabbit IgG full length Log in to see Polyclonal
1 ABIN732985 IHC (p) WB Biotin Rabbit IgG AA 1360-1410 Log in to see Polyclonal
1 ABIN2619929 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2879539 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-DAP Kinase 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-DAP Kinase 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 1 Antibodies 17 Antibodies 45 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 5 Antibodies 18 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 12 Antibodies
Western Blotting (WB) 12 Antibodies 30 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 11 Antibodies
ELISA (Capture) 1 Antibodies

General

Antigen Death-Associated Protein Kinase 1 (DAPK1) Antibodies
Epitope AA 1360-1410
(19), (15), (14), (14), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(92), (48), (23), (4), (2), (1), (1)
Host Rabbit
(85), (7)
Clonality
Polyclonal
Conjugate This DAP Kinase 1 antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(62), (45), (32), (15), (14), (12), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-DAP Kinase 1 Antibody

Target Details DAP Kinase 1 Application Details Handling References for anti-DAP Kinase 1 Antibody (ABIN732983) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DAPK1
Isotype IgG

Target Details DAP Kinase 1

Product Details anti-DAP Kinase 1 Antibody Application Details Handling References for anti-DAP Kinase 1 Antibody (ABIN732983) Images back to top
Antigen
Alternative Name Dapk1 (DAPK1 Antibody Abstract)
Background

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.

Subcellular location: Cytoplasm


Synonyms: DAPK, Death-associated protein kinase 1, DAP kinase 1, DAPK1
Gene ID 1612
UniProt P53355
Pathways MAPK Signaling, Interferon-gamma Pathway

Application Details

Product Details anti-DAP Kinase 1 Antibody Target Details DAP Kinase 1 Handling References for anti-DAP Kinase 1 Antibody (ABIN732983) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-DAP Kinase 1 Antibody Target Details DAP Kinase 1 Application Details References for anti-DAP Kinase 1 Antibody (ABIN732983) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-DAP Kinase 1 Antibody (ABIN732983)

Product Details anti-DAP Kinase 1 Antibody Target Details DAP Kinase 1 Application Details Handling Images back to top
Product cited in:

Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, 2010

Images

Product Details anti-DAP Kinase 1 Antibody Target Details DAP Kinase 1 Application Details Handling References for anti-DAP Kinase 1 Antibody (ABIN732983) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DAP Kinase 1 antibody (Death-Associated Protein Kinase 1) (AA 1360-1410) (ABIN732983) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-DAPK1 Po...