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|Antigen||Heat Shock Transcription Factor 4 (HSF4) Antibodies|
|Epitope||N-Term, AA 99-128 Alternatives|
|Conjugate||This HSF4 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|4 references available|
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Product Details anti-HSF4 AntibodyTarget Details HSF4 Application Details Handling References for anti-HSF4 Antibody (ABIN952699) Images
|Specificity||This antibody recognizes Human Heat shock factor 4 / HSF4 (N-term).|
|Purification||Protein A column, followed by peptide affinity purification|
|Immunogen||KLH conjugated synthetic peptide between 99-128 amino acids from the N-terminal region of humanHeat shock factor 4 / HSF4|
Target Details HSF4Product Details anti-HSF4 Antibody Application Details Handling References for anti-HSF4 Antibody (ABIN952699) Images back to top
|Alternative Name||Heat Shock Factor 4 / HSF4 (HSF4 Antibody Abstract)|
|Background||Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been describedSynonyms: HSF-4, HSTF4, Heat shock transcription factor 4|
|Molecular Weight||53011 Da|
Application DetailsProduct Details anti-HSF4 Antibody Target Details HSF4 Handling References for anti-HSF4 Antibody (ABIN952699) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-HSF4 Antibody Target Details HSF4 Application Details References for anti-HSF4 Antibody (ABIN952699) Images back to top
|Buffer||PBS containing 0.09 % (W/V) Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-HSF4 Antibody (ABIN952699)Product Details anti-HSF4 Antibody Target Details HSF4 Application Details Handling Images back to top
Enoki, Mukoda, Furutani et al.: "DNA-binding and transcriptional activities of human HSF4 containing mutations that associate with congenital and age-related cataracts." in: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 749-53, 2010 (PubMed).
Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).
Ma, Zhang, Li et al.: "[Construction of eukaryotic plasmid expression Hsf4b and phosphorylation of Hsf4b by MAP kinase P38]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 4, pp. 325-8, 2010 (PubMed).
Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).
ImagesProduct Details anti-HSF4 Antibody Target Details HSF4 Application Details Handling References for anti-HSF4 Antibody (ABIN952699) back to top