HSF4 antibody (Middle Region)

Catalog No. ABIN2779779

There is 1 publication for this product available. The Rabbit Polyclonal anti-HSF4 antibody is suitable to detect HSF4 in samples from Human and Rabbit. It has been validated for WB.

Quick Overview for HSF4 antibody (Middle Region) (ABIN2779779)

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSF4 Antibody

Binding Specificity: Middle Region

Purpose: HSF4 Antibody - middle region

Sequence: VTLRQSHGQQ HRVIGKLIQC LFGPLQAGPS NAGGKRKLSL MLDEGSSCPT

Predicted Reactivity: Human: 100%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against HSF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSF4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32652-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSF4 antibody (ABIN2779779)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for HSF4

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Alternative Name: HSF4

Background:

Background Information: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

Gene Name: Heat shock transcription factor 4

Alternative Symbols: CTM, CTRCT5

Protein Name: Heat shock factor protein 4

Molecular Weight: 50kDa

Gene ID: 3299

NCBI Accession: NP_001529

UniProt: Q9ULV5

Pathways: MAPK Signaling