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Browse our MAP2K1 (MAP2K1) ELISA Kits

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Mitogen-Activated Protein Kinase Kinase 1 ELISA Kits (MAP2K1)
On www.antibodies-online.com are 28 Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) ELISA Kits from 10 different suppliers available. Additionally we are shipping MAP2K1 Antibodies (595) and MAP2K1 Proteins (21) and many more products for this protein. A total of 682 MAP2K1 products are currently listed.
Synonyms:
ATMEK1, CFC3, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MAPKK1, MEK, mek-2, MEK1, MEKK1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK, Prkmk1, si:ch211-242m18.2, wu:fj56a12, wu:fj61b01, zgc:56557
list all ELISA KIts Gene Name GeneID UniProt
MAP2K1 170851 Q01986
MAP2K1 5604 Q02750
MAP2K1 26395 P31938

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More ELISA Kits for MAP2K1 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Data show that src (show SRC ELISA Kits) kinases (SRC (show SRC ELISA Kits)) and mitogen-activated protein kinase kinase 1 (MEK) co-inhibition by saracatinib and PD0325901 respectively can be broadly effective in tumor growth control of a wide panel of non-small cell lung cancer (NSCLC) cell lines.

  2. at clinically relevant concentrations, cDDP binds to and inhibits MEK1/2 and both the binding and inhibitory activity are related to its interaction with Cu bound to MEK1/2

  3. Endocytosis separates EGF (show EGF ELISA Kits) receptors from endogenous fluorescently labeled HRas (show HRAS ELISA Kits) and diminishes receptor signaling to MAP kinases in endosomes.

  4. Studies indicate that concurrent inhibition of proto-oncogene (show RAB1A ELISA Kits) protein B (show LEPREL2 ELISA Kits)-raf (BRAF (show BRAF ELISA Kits)) and Map kinase (show MAPK1 ELISA Kits) kinase (MEK) improved the most effective therapeutic modality as compared as single BRAF (show BRAF ELISA Kits) or MEK inhibition for patients with metastatic melanoma (MM).

  5. Findings suggest that triple therapy directed against BRAF (show BRAF ELISA Kits)/MEK/ErbB3 (show ERBB3 ELISA Kits) may be able to provide durable control of BRAF (show BRAF ELISA Kits) mutated metastatic melanoma.

  6. MEK1 levels are upregulated at transcriptional level whereas MEK2 (show MAP2K2 ELISA Kits) levels are downregulated at posttranslational level.

  7. NOTCH1 (show NOTCH1 ELISA Kits), TP53 (show TP53 ELISA Kits), and MAP2K1 mutations in splenic diffuse red pulp small B-cell lymphoma are associated with progressive disease.

  8. MEK1/2 inhibitor trametinib showed similar PFS and a response rate as docetaxel in patients with previously treated KRAS-mutant-positive non-small cell lung carcinoma.

  9. Findings establish that the convergence of 2 distinct Ras effector pathways on mammalian target of rapamycin (show FRAP1 ELISA Kits) signaling maintains neurofibromatosis type 1 (show NF1 ELISA Kits) mouse optic glioma growth.

  10. MEK1 Mutations are associated with Low-grade Serous Ovarian Cancer.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Aberrant phosphorylation of AKT (show AKT1 ELISA Kits) and MEK (show MDK ELISA Kits) signalling pathways was identified in cells carrying mutant huntingtin (show HTT ELISA Kits).

  2. An essential function for MEK1 in macrophages in regulating the ERK1/2 (show MAPK1/3 ELISA Kits) and STAT4 (show STAT4 ELISA Kits) pathways in response to TLR4 (show TLR4 ELISA Kits) activation.

  3. Nuclear enrichment of MEK1 physically sequesters peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG ELISA Kits)), inhibiting adipogenesis and disrupting ERK (show EPHB2 ELISA Kits) signaling.

  4. MEK1 is inhibited by phosphorylation at Thr (show TRH ELISA Kits)-292/286 by Cdk5 (show CDK5 ELISA Kits), ERK (show EPHB2 ELISA Kits), and Cdk1 (show CDK1 ELISA Kits).

  5. The effect of Akt1 (show AKT1 ELISA Kits) and Mek1 on extracellular matrix synthesis was reconciled through the activation of p70 S6-kinase (show PRKACB ELISA Kits).

  6. Homologous recombination efficiency enhanced by inhibition of MEK and GSK3beta.

  7. Data show that Treg cell-specific expression of activated MAP Kinase Kinase 1 (MEK1) led to dysregulation of Treg function.

  8. Both ACE (show ACE ELISA Kits) inhibition and MEK1/2 inhibition have beneficial effects on left ventricular function in Lmna (show LMNA ELISA Kits)(H222P/H222P) mice and both drugs together have a synergistic benefit when initiated after the onset of left ventricular dysfunction.

  9. both MEK1 and MEK2 (show MAP2K2 ELISA Kits) have crucial roles in the integration of mesenchymal and epithelial signals essential for the development of the entire respiratory tract

  10. rapamycin treatment led to an increased MKP1 (show DUSP1 ELISA Kits) expression in BMDM from WT but failed to do so in BMDMs lacking the AKT1 (show AKT1 ELISA Kits) isoform or MEK1 and MEK2 (show MAP2K2 ELISA Kits).

Xenopus laevis Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. in FGFR1 (show FGFR1 ELISA Kits) signalling JNK1 (show MAPK8 ELISA Kits) phosphorylation depends on ERK2 (show MAPK1 ELISA Kits)

  2. The data demonstrate that ERK (show MAPK1 ELISA Kits) phosphorylation of UBF prevents DNA bending by its first two HMG (show SSRP1 ELISA Kits) boxes, leading to a cooperative unfolding of the enhancesome

  3. We propose that Erk2 MAP kinase (show MAPK1 ELISA Kits) phosphorylation of Vg1RBP (show IGF2BP3 ELISA Kits) regulates the protein:protein-mediated association of Vg1 mRNP with the cytoskeleton and/or ER.

Rabbit Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Extracellular signal-regulated kinase (ERK (show MAPK1 ELISA Kits)) pathway plays a role in dedifferentiation of rabbit articular chondrocytes.

  2. KSR (show KSR1 ELISA Kits) interacts with a regulatory Raf (show RAF1 ELISA Kits) molecule in cis (show CISH ELISA Kits) to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf (show RAF1 ELISA Kits) molecule in trans

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Data indicate that MEKK2 (show MAP3K2 ELISA Kits) is required for the mekk1 (show MAP3K1 ELISA Kits), mkk1 mkk2 (show MAP2K2 ELISA Kits), and mpk4 (show MAPK4 ELISA Kits) autoimmune phenotypes.

  2. Data suggest that the MEKK1 (show MAP3K1 ELISA Kits)-MKK1/MKK2 (show MAP2K2 ELISA Kits)-MPK4 (show MAPK4 ELISA Kits) kinase cascade negatively regulates MEKK2 (show MAP3K2 ELISA Kits) and activation of MEKK2 (show MAP3K2 ELISA Kits) triggers SUMM2-mediated immune responses.

  3. miR (show MYLIP ELISA Kits)-1826 plays an important role as tumor suppressor via CTNNB1 (show CTNNB1 ELISA Kits)/MEK1/VEGFC (show VEGFC ELISA Kits) downregulation in bladder cancer.

  4. ETS1 (show ETS1 ELISA Kits) is probably mediating high CIP2A (show KIAA1524 ELISA Kits) expression in human cancers with increased EGFR (show EGFR ELISA Kits)-MEK1/2-ERK (show MAPK1 ELISA Kits) pathway activity

  5. An analysis of the interation of MEKK1 (show MAP3K1 ELISA Kits) and MEK1 in response to wounding stress in A. thaliana seedlings is presented.

  6. This study demonstrated that the MKK1 signalling pathway modulates the expression of genes responding to elicitors and plays an important role in pathogen defence.

  7. These results suggest that the formation of SUMO-1 (show SUMO1 ELISA Kits) foci is regulated by the MEK-ERK (show MAPK1 ELISA Kits) pathway and may induce apoptosis.

  8. AtMEK1 is a crucial mediator in plant stress signal transduction.

  9. double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 (show MAP2K2 ELISA Kits) is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 (show MAP3K1 ELISA Kits) and mpk4 (show MAPK4 ELISA Kits) mutants

  10. Activation of MPK4 (show MAPK4 ELISA Kits) by flg22 is impaired in the mkk1 mkk2 (show MAP2K2 ELISA Kits) double mutants, suggesting that MKK1 and MKK2 (show MAP2K2 ELISA Kits) function together with MPK4 (show MAPK4 ELISA Kits) and MEKK1 (show MAP3K1 ELISA Kits) in a MAP kinase (show MAPK1 ELISA Kits) cascade to negatively regulate innate immune responses in plants.

MAP2K1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Alternative names and synonyms associated with MAP2K1

  • mitogen activated protein kinase kinase 1 (Map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (MAP2K1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (Map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (MEK1) Elisa Kit
  • ATMEK1 Elisa Kit
  • CFC3 Elisa Kit
  • F20B18.180 Elisa Kit
  • F20B18_180 Elisa Kit
  • MAP kinase/ ERK kinase 1 Elisa Kit
  • MAPKK1 Elisa Kit
  • MEK Elisa Kit
  • mek-2 Elisa Kit
  • MEK1 Elisa Kit
  • MEKK1 Elisa Kit
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE Elisa Kit
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Elisa Kit
  • MKK1 Elisa Kit
  • NMAPKK Elisa Kit
  • Prkmk1 Elisa Kit
  • si:ch211-242m18.2 Elisa Kit
  • wu:fj56a12 Elisa Kit
  • wu:fj61b01 Elisa Kit
  • zgc:56557 Elisa Kit

Protein level used designations for MAP2K1

ERK activator kinase 1 , MAP kinase kinase 1 , MAP kinase/Erk kinase 1 , MAPK/ERK kinase 1 , MAPKK 1 , dual specificity mitogen-activated protein kinase kinase 1 , mitogen-activated protein kinase kinase 1 , MEK 1 , protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) , dual specificity mitogen activated protein kinase kinase 1 , mitogen activated protein kinase kinase 1 , protein kinase, mitogen activated, kinase 1, p45 , MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2) , MEK1

GENE ID SPECIES
170851 Rattus norvegicus
5604 Homo sapiens
478347 Canis lupus familiaris
26395 Mus musculus
379991 Xenopus laevis
415549 Gallus gallus
533199 Bos taurus
406728 Danio rerio
100009316 Oryctolagus cuniculus
100233191 Sus scrofa
828713 Arabidopsis thaliana
450188 Pan troglodytes
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