MEK1 Products
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Categories
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008].
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Featured MEK1 Categories
MEK1 Antibodies
High quality antibodies with extensive validation data.
MEK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MEK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MEK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validations
- (3)
- (1)
Cat. No.
ABIN686482
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN1499374
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (9)
Cat. No.
ABIN1499381
Quantity
100 μL
Datasheet
Datasheet
Recommended MEK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (4)
Cat. No.
ABIN1981725
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN1981724
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957865
Quantity
96 tests
Datasheet
Datasheet
Recommended MEK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5570512
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569647
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570511
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MEK1 products
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).: "Follicular fluid meiosis-activating sterol (FF-MAS) promotes meiotic resumption via the MAPK pathway in porcine oocytes." in: Theriogenology, (2019) (PubMed).
: "Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer." in: Cancer medicine, Vol. 7, Issue 4, pp. 1546-1559, (2018) (PubMed).
: "EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer." in: Molecular medicine reports, Vol. 17, Issue 6, pp. 7875-7885, (2018) (PubMed).
: "Cinobufacini inhibits epithelial-mesenchymal transition of human hepatocellular carcinoma cells through c-Met/ERK signaling pathway." in: Bioscience trends, Vol. 12, Issue 3, pp. 291-297, (2018) (PubMed).
: "MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 10, (2018) (PubMed).
: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).
: "Identification of Biomarkers of Impaired Sensory Profiles among Autistic Patients." in: PLoS ONE, Vol. 11, Issue 11, pp. e0164153, (2016) (PubMed).
: "Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 254, Issue 11, pp. 2217-2226, (2016) (PubMed).
: "Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 16, Issue 8, pp. 3509-15, (2015) (PubMed).
Synonyms and alternative names related to MEK1
mitogen activated protein kinase kinase 1 (Map2k1), mitogen-activated protein kinase kinase 1 (MAP2K1), mitogen-activated protein kinase kinase 1 (Map2k1), mitogen-activated protein kinase kinase 1 L homeolog (map2k1.L), mitogen-activated protein kinase kinase 1 (map2k1), MAP kinase/ ERK kinase 1 (MEK1), ATMEK1, CFC3, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MAPKK1, MEK, mek-2, Mek1, MEK1, MEKK1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK, PRKMK1, Prkmk1, si:ch211-242m18.2, wu:fj56a12, wu:fj61b01, zgc:56557Protein level used designations for MEK1
- ERK activator kinase 1
- MAP kinase kinase 1
- MAP kinase/Erk kinase 1
- MAPK/ERK kinase 1
- MAPKK 1
- dual specificity mitogen-activated protein kinase kinase 1
- mitogen-activated protein kinase kinase 1
- MEK 1
- protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
- dual specificity mitogen activated protein kinase kinase 1
- mitogen activated protein kinase kinase 1
- protein kinase, mitogen activated, kinase 1, p45
- MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2)
- MEK1
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