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anti-Human MCL-1 antibody for Enzyme Immunoassay

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Epitope
BH3 Domain
32
23
22
15
15
13
13
13
11
9
9
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
297
101
68
9
8
5
4
3
2
2
1
1
Host
Rabbit
205
82
18
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
7
6
5
3
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
250
123
103
63
60
31
31
22
21
13
7
5
1
Supplier
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Catalog No. ABIN356822
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088188547 ABIN500252 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 1
0.00088188547 ABIN500254 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 1
0.00088188547 ABIN500256 EIA IF WB Rabbit IgG Center Log in to see Polyclonal 1
0.00088188547 ABIN400763 EIA IHC (p) WB Mouse IgG1 Log in to see 8C6D4B1
0.00088188547 ABIN1108171 EIA IHC (p) WB Mouse IgG1 Log in to see 8C6 (8C6D4B1)

Top referenced anti-MCL-1 antibody for Enzyme Immunoassay

Similar anti-MCL-1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 33 Antibodies 117 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 6 Antibodies
Flow Cytometry (FACS) 7 Antibodies 31 Antibodies
Immunocytochemistry (ICC) 8 Antibodies 30 Antibodies
Immunofluorescence (IF) 9 Antibodies 60 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 63 Antibodies
Immunochromatography (IC) 7 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope BH3 Domain
(32), (23), (22), (15), (15), (13), (13), (13), (11), (9), (9), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(297), (101), (68), (9), (8), (5), (4), (3), (2), (2), (1), (1)
Host Rabbit
(205), (82), (18), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (7), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(250), (123), (103), (63), (60), (31), (31), (22), (21), (13), (7), (5), (1)
Pubmed 1 reference available
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN356822) Images
Specificity This antibody is specific to MCL1 (BH3 Domain).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody was developed against a synthetic peptide selected from the central region (BH3 domain) of human Mcl-1.
Isotype Ig

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN356822) Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
Gene ID 4170, 9606
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN356822) Images back to top
Application Notes ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN356822) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MCL-1 Antibody (ABIN356822)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Background publications

Johnson, Lucas, Muthusamy, Smith, Edwards, De Lay, Croce, Grever, Byrd: "Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia." in: Blood, Vol. 108, Issue 4, pp. 1334-8, 2006

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN356822) back to top
Supplier Images
 image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (BH3 Domain) (ABIN356822) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (BH3 Domain) antibody
 image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (BH3 Domain) (ABIN356822) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (BH3 Domain) antibody (Image 2)