anti-Human MCL-1 antibody for Immunocytochemistry

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • Mcl-1
  • BCL2L3
  • EAT
  • MCL1-ES
  • MCL1L
  • MCL1S
  • TM
  • bcl2-L-3
  • mcl1/EAT
  • mcl-1
  • myeloid cell leukemia sequence 1
  • myeloid cell leukemia sequence 1 (BCL2-related)
  • Mcl1
  • MCL1
Reactivity
Human
332
127
83
13
13
10
8
3
3
3
2
1
1
1
Host
Mouse
221
97
22
2
Clonality
Monoclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
6
5
5
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
283
141
116
93
80
44
31
29
26
25
6
5
5
1
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Catalog No. ABIN969485
$ 345.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
26.375908 ABIN4333158 ICC IF WB Rabbit Center Log in to see Polyclonal
1 ABIN2869169 ELISA ICC IHC WB Mouse IgG1 Log in to see 8C6-8C6D4B1 1
1 ABIN5627289 ELISA ICC IF WB Rabbit IgG AA 220-270 Log in to see Polyclonal
1 ABIN2855261 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN207776 ICC WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN207760 ICC WB Rabbit N-Term Log in to see Polyclonal
1 ABIN214512 ICC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4333174 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN4333157 ELISA ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 8C6D4B1
1 ABIN4333167 ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1736826 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4333172 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN4333171 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN1869117 ICC IHC IP WB Rabbit IgG AA 6-328 Log in to see Polyclonal
1 ABIN1030511 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1030997 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN1031455 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN4333163 ICC IF IHC WB Rabbit Log in to see Polyclonal
1 ABIN4904325 FACS ICC IF IHC IP WB Rabbit IgG Log in to see
1 ABIN4231536 ELISA ICC IF IHC (fro) IHC (p) FITC Mouse IgG1 Log in to see 8C6D4B1

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Reactivity Human
(332), (127), (83), (13), (13), (10), (8), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(221), (97), (22), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(283), (141), (116), (93), (80), (44), (31), (29), (26), (25), (6), (5), (5), (1)
Pubmed 2 references available
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 antibody (ABIN969485) Images
Purification Purified
Immunogen Purified recombinant fragment of human MCL-1 expressed in E. Coli.
Clone 8C6
Isotype IgG1

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 antibody (ABIN969485) Images back to top
Antigen
Alternative Name MCL-1 (MCL1 Antibody Abstract)
Background Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.
Molecular Weight 37 kDa
Gene ID 4170
HGNC 4170
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 antibody (ABIN969485) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 antibody (ABIN969485) Images back to top
Format Liquid
Buffer PBS containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-MCL-1 antibody (ABIN969485)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Product cited in:

Richert, Schwertfeger, Ryder, Anderson: "An atlas of mouse mammary gland development." in: Journal of mammary gland biology and neoplasia, Vol. 5, Issue 2, pp. 227-41, 2001

MacLachlan, Hébert: "Statement concerning euthanasia and physician-assisted suicide. Ethics Committee of the College of Family Physicians of Canada." in: Canadian family physician Médecin de famille canadien, Vol. 46, pp. 254-6, 264-7, 2000

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 antibody (ABIN969485) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody (ABIN969485) Figure 1: Confocal immunofluorescence analysis of HepG2 cells using MCL1 mouse mAb (g...
Immunohistochemistry (IHC) image for anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody (ABIN969485) Figure 2: Immunohistochemical analysis of paraffin-embedded human lymphnode tissues u...
Western Blotting (WB) image for anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody (ABIN969485) Figure 3: Western blot analysis using MCL1 mouse mAb against Hela (1), BCBL-1 (2), Ju...