anti-Rat (Rattus) MCL-1 antibody for Enzyme Immunoassay

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • Mcl-1
  • BCL2L3
  • EAT
  • MCL1-ES
  • MCL1L
  • MCL1S
  • TM
  • bcl2-L-3
  • mcl1/EAT
  • mcl-1
  • myeloid cell leukemia sequence 1
  • myeloid cell leukemia sequence 1 (BCL2-related)
  • Mcl1
  • MCL1
Epitope
C-Term
30
22
18
17
15
15
14
13
12
9
7
6
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
327
125
81
13
13
10
8
3
3
3
2
1
1
1
Host
Rabbit
215
98
22
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
6
5
5
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
279
139
115
92
78
44
31
30
26
25
5
5
5
1
Supplier
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Catalog No. ABIN5555002
$ 375.38
Plus shipping costs $45.00

Similar anti-MCL-1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 22 Antibodies 46 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 2 Antibodies 14 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 10 Antibodies
Immunofluorescence (IF) 8 Antibodies 12 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies 26 Antibodies
Immunohistochemistry (IHC) 19 Antibodies 30 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 54 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope C-Term
(30), (22), (18), (17), (15), (15), (14), (13), (12), (9), (7), (6), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(327), (125), (81), (13), (13), (10), (8), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(215), (98), (22), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(279), (139), (115), (92), (78), (44), (31), (30), (26), (25), (5), (5), (5), (1)
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling Images
Specificity This antibody detects MCL1 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Ion exchange chromatography
Immunogen Mcl-1 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy-terminus of human Mcl-1.
Isotype IgG

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival (reviewed in 1). While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak (2,3). Mcl-1 was originally identified in differentiating myeloid cells (4), but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis (5) and for the development and maintenance of B and T lymphocytes in animals (3). Mcl-1 exists as at least two distinct isoforms designated Mcl-1L and Mcl-1S. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death (6).Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
Gene ID 4170
NCBI Accession NP_068779
UniProt Q07820
Research Area Apoptosis/Necrosis, Cancer
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling Images back to top
Application Notes ELISA: Western blot: 1 to 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.