You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Meriones) MCL-1 antibody for Western Blotting

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Reactivity
Human, Mouse (Murine), Rat (Meriones)
331
110
73
10
9
5
5
3
3
2
1
1
Host
Rabbit
222
98
20
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
7
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
282
142
114
86
83
52
32
27
25
22
7
6
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN2801930
$ 324.50
Plus shipping costs $45.00

Top referenced anti-MCL-1 antibody for Western Blotting

Similar anti-MCL-1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Meriones)
Western Blotting (WB) 276 Antibodies 72 Antibodies 1 Antibodies
Immunoprecipitation (IP) 24 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 86 Antibodies 16 Antibodies
Immunohistochemistry (IHC) 114 Antibodies 22 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 26 Antibodies 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunofluorescence (IF) 83 Antibodies 12 Antibodies
Immunocytochemistry (ICC) 51 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Meriones)
(331), (110), (73), (10), (9), (5), (5), (3), (3), (2), (1), (1)
Host Rabbit
(222), (98), (20), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(282), (142), (114), (86), (83), (52), (32), (27), (25), (22), (7), (6), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN2801930) Images
Isotype IgG

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN2801930) Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3
Molecular Weight 37337 Da
Gene ID 4170
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN2801930) Images back to top
Application Notes WB - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN2801930) Images back to top
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-MCL-1 Antibody (ABIN2801930)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Product cited in:

Akgul, Turner, White, Edwards: "Functional analysis of the human MCL-1 gene." in: Cellular and molecular life sciences : CMLS, Vol. 57, Issue 4, pp. 684-91, 2000

Bingle, Craig, Swales, Singleton, Zhou, Whyte: "Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 22136-46, 2000

Umezawa, Maruyama, Inazawa, Imai, Takano, Hata: "Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3." in: Cell structure and function, Vol. 21, Issue 2, pp. 143-50, 1996

Background publications

Bae, Leo, Hsu, Hsueh: "MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain." in: The Journal of biological chemistry, Vol. 275, Issue 33, pp. 25255-61, 2000

Kozopas, Yang, Buchan, Zhou, Craig: "MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3516-20, 1993

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN2801930) back to top
Supplier Images
Western Blotting (WB) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN2801930) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody
Western Blotting (WB) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN2801930) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody (Image 2)