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anti-Primate PAK2 antibody for Immunofluorescence

Recommended PAK2 Antibody (supplied by: Log in to see )

Antigen
P21-Activated Kinase 2 (PAK2) Antibodies
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • cb422
  • D16Ertd269e
  • gamma-PAK
  • kinase
  • mKIAA4182
  • PAK-2
  • pak2
  • Pak3
  • pak65
  • PAK65
  • PAKgamma
  • pakgamma
  • PAKI
  • si:dz198m22.1
  • wu:fb71h01
  • zgc:91798
Reactivity
Human, Primate
170
74
73
6
5
Host
Mouse
156
14
Clonality
Monoclonal
Conjugate
This PAK2 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
150
97
72
21
13
5
3
2
2
1
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Catalog No. ABIN2869426
$ 464.29
Plus shipping costs $45.00

Top referenced anti-PAK2 antibody for Immunofluorescence

Similar anti-PAK2 Antibodies

Application / Reactivity Primate Human
Immunofluorescence (IF) 1 Antibodies 15 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 74 Antibodies
Western Blotting (WB) 1 Antibodies 153 Antibodies
ELISA 97 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies

General

Antigen P21-Activated Kinase 2 (PAK2) Antibodies
Reactivity Human, Primate
(170), (74), (73), (6), (5)
Host Mouse
(156), (14)
Clonality
Monoclonal
Conjugate This PAK2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(150), (97), (72), (21), (13), (5), (3), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-PAK2 Antibody

Target Details PAK2 Application Details Handling References for anti-PAK2 Antibody (ABIN2869426) Images
Specificity Purified recombinant fragment of PAK2 expressed in E. Coli.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen Purified recombinant fragment of PAK2 expressed in E. Coli.
Isotype IgG1

Target Details PAK2

Product Details anti-PAK2 Antibody Application Details Handling References for anti-PAK2 Antibody (ABIN2869426) Images back to top
Antigen
Alternative Name PAK2 (PAK2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 58043 DA
Gene ID 12406
NCBI Accession NP_002568
UniProt Q13177
Research Area Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Cell Structure, Cell Cycle, Signaling, Chromatin
Pathways MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-PAK2 Antibody Target Details PAK2 Handling References for anti-PAK2 Antibody (ABIN2869426) Images back to top
Application Notes The suggested dilution is: Western Bloting: = 1:500 - 2000. Immunohistochemistry: = 1:200 - 1000. Immunofluorescence: = 1:200 - 1000.
Comment

Background: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Restrictions For Research Use only

Handling

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details References for anti-PAK2 Antibody (ABIN2869426) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-PAK2 Antibody (ABIN2869426)

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details Handling Images back to top
Background publications

Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007

Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004