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anti-Human SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • AA673258
  • SIR2
  • Sir2
  • Sir2a
  • Sir2alpha
  • SIR2L1
  • sir2l1
  • sirtuin
  • sirtuin 1
Epitope
AA 20-60, pSer47
30
20
20
17
17
16
13
12
10
5
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
252
103
46
8
8
6
4
4
3
3
2
2
2
2
1
1
Host
Rabbit
182
57
25
7
2
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
14
12
9
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
212
112
57
42
40
33
28
25
11
5
4
4
4
2
1
1
Supplier
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Catalog No. ABIN745658
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34288716 ABIN615980 EIA IHC (p) WB Goat AA 577-590, Internal Region Log in to see Polyclonal
0.34288716 ABIN239843 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN729853 IF (p) IHC (p) WB Rabbit IgG AA 192-242 Log in to see Polyclonal 1
0.0008982679 ABIN372326 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN258470 ICC IHC (fro) IF IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see E104
0.0008982679 ABIN1109014 EIA FACS IF IHC (p) WB Mouse IgG1 Log in to see 1F3 2
0.0008982679 ABIN565071 IF IHC (p) ELISA WB Mouse IgG1 kappa AA 456-555, partial Log in to see 7B7 3
0.0008982679 ABIN214144 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.0008982679 ABIN614713 EIA IF IHC (p) WB Mouse IgG1 AA 456-555 Log in to see 7B7
0.0008982679 ABIN1493902 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal
0.0008982679 ABIN746003 IF (p) IHC (p) WB Rabbit IgG AA 1-50, pSer27 Log in to see Polyclonal
0.0008982679 ABIN1723581 IF IHC (p) ELISA WB Mouse IgG1 kappa AA 456-555 Log in to see 7B7
0.0008982679 ABIN679028 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN445114 ICC IF IHC (p) IHC WB Rabbit IgG Ser47 Log in to see EPR2849Y
0.0008982679 ABIN1739281 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN745667 IHC (p) WB HRP Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
0.0008982679 ABIN745660 IHC (p) WB Biotin Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
0.0008982679 ABIN729855 IHC (p) WB Biotin Rabbit IgG AA 192-242 Log in to see Polyclonal
0.0008982679 ABIN729862 IHC (p) WB HRP Rabbit IgG AA 192-242 Log in to see Polyclonal
0.0008982679 ABIN574445 IF IHC (p) ELISA WB Mouse IgG1, kappa Log in to see 7B7

Top referenced anti-SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SIRT1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 41 Antibodies 95 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 27 Antibodies
Immunofluorescence (IF) 10 Antibodies 43 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 15 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 68 Antibodies
Chromatin Immunoprecipitation (ChIP) 4 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 11 Antibodies
Immunochromatography (IC) 2 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope AA 20-60, pSer47
(30), (20), (20), (17), (17), (16), (13), (12), (10), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(252), (103), (46), (8), (8), (6), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(182), (57), (25), (7), (2)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(14), (12), (9), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(212), (112), (57), (42), (40), (33), (28), (25), (11), (5), (4), (4), (4), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human SirT1 around the phosphorylation site of Ser47
Isotype IgG

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Antigen
Alternative Name Sirt1 (SIRT1 Antibody Abstract)
Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Subcellular location: Cytoplasm, Nucleus


Synonyms: SIR2L1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SIRT1
Gene ID 23411
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-SIRT1 Antibody (ABIN745658)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Product cited in:

Suzuki, Bandoski, Bartlett: "Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling." in: Free radical biology & medicine, Vol. 89, pp. 369-378, 2015

Suzuki, Bartlett: "Sirtuin1 and autophagy protect cells from fluoride-induced cell stress." in: Biochimica et biophysica acta, Vol. 1842, Issue 2, pp. 245-55, 2014

Images

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 20-60) (ABIN745658) Formalin-fixed and paraffin embedded rat brain labeled with Anti-Phospho-SIRT1(Ser47)...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-SIRT1 antibody (Sirtuin 1) (AA 20-60) (ABIN745658) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-SI...