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anti-Mouse (Murine) beta Endorphin Antibodies:
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Carp Polyclonal beta Endorphin Primary Antibody for IEM, ICC - ABIN617878
Pinessi, Rainero, de Gennaro, Violante, Cassano, Matera, Cesano: Cerebrospinal fluid and plasma concentrations of POMC-related peptides in multiple sclerosis. in Annals of the New York Academy of Sciences 1992
Show all 21 Pubmed References
Human Monoclonal beta Endorphin Primary Antibody for IHC (fro), IF - ABIN111318
Andjelkov, Elvenes, Figenschau, Bjorkoy, Knutsen, Seternes, Johansen: Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage. in Cell biochemistry and function 2006
Show all 2 Pubmed References
Rat (Rattus) Polyclonal beta Endorphin Primary Antibody for IF, IHC - ABIN188513
Liu, Zeng, Zhou, Theodorsson, Fahrenkrug, Reinscheid: Molecular fingerprint of neuropeptide S-producing neurons in the mouse brain. in The Journal of comparative neurology 2011
The data show that somatic MORs in POMC (show POMC Antibodies) neurons couple to multiple effectors that have differential sensitivity to desensitization of the receptor.
These findings indicate that the relevance of AgRP (show AGRP Antibodies) to POMC (show POMC Antibodies) neuron GABA connectivity depends on the state of AgRP (show AGRP Antibodies) neuron activity and suggest that different types of transmitter release should be considered when circuit mapping.
these data unmasked a role for mitochondrial fission in leptin (show LEP Antibodies) sensitivity and glucose sensing of POMC (show POMC Antibodies) neurons.
it is suggested that the suppression of NeuroD1 (show NEUROD1 Antibodies) expression and the inhibition of NeuroD1 (show NEUROD1 Antibodies)/E-box interaction may play an important role in the Gc-mediated negative regulation of Pomc (show POMC Antibodies).
To clarify the functional roles of the AKT (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway in the hippocampal neurons, we generated conditional knockout mice harboring the deletion of Pten (Pten (show PTEN Antibodies)-cKO) in Proopiomelanocortin (show POMC Antibodies)-expressing neurons.
Epo (show EPO Antibodies) regulates hypothalamus POMC (show POMC Antibodies) expression via STAT3 (show STAT3 Antibodies) activation.
Data suggest that the solitary tract pro-opiomelanocortin (show POMC Antibodies) (NTSPOMC) neurons were involved in cardiorespiratory control and endogenous analgesia.
hypothalamic arcuate nucleus (Arc (show NOL3 Antibodies))POMC (show POMC Antibodies)-deficient mice, which develop severe obesity and insulin (show INS Antibodies) resistance, unexpectedly exhibit improved glucose tolerance and remain protected from hyperglycemia via decreased renal GLUT2 (show SLC2A2 Antibodies) expression and glycosuria.
Hypomethylation of POMC (show POMC Antibodies) promoter occurred in the hypothalamus of the high sucrose diet offspring compared with controls.
Together, these results suggest that alpha-MSH alleviates Dex-induced damages to cultured osteoblasts through activating MC4R (show MC4R Antibodies)-SphK1 (show SPHK1 Antibodies) signaling.
Elevated ACTH (show POMC Antibodies) secretion is associated with Cushing's syndrome.
a novel p53 (show TP53 Antibodies)/POMC (show POMC Antibodies)/Galphas (show GNAS Antibodies)/SASH1 (show SASH1 Antibodies) autoregulatory positive feedback loop is regulated by SASH1 (show SASH1 Antibodies) mutations to induce pathological hyperpigmentation phenotype.
Data suggest that alpha-MSH enhances cell adhesion to fibronectin (show FN1 Antibodies) in primary mixed synoviocytes obtained from osteoarthritis patients; alpha-MSH reduces secretion of cytokines (TNF (show TNF Antibodies), IL-6 (show IL6 Antibodies) and IL-8 (show IL8 Antibodies)) in such synoviocyte cultures.
Data suggest that the first screening step diagnosis for pituitary adenoma was determined based upon immunohistochemical (IHC) scores for Pit-1 (show POU1F1 Antibodies), SF-1 (show NR5A1 Antibodies), and ACTH (show POMC Antibodies).
The aim of this survey is to evaluate the association of genetic variants of melanocortin-4-receptor (MC4R (show MC4R Antibodies)), pro-opiomelanocortin (POMC (show POMC Antibodies)), apolipoprotein E (APOE (show APOE Antibodies)) and agouti-related protein (AGRP (show AGRP Antibodies)) with obesity in the North Indian population.
The expression of Pomc (show POMC Antibodies) mRNA was stimulated in the arcuate nucleus after skin exposure to UVB.
hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-34a can regulate the CRH (show CRH Antibodies)/CRHR1 (show CRHR1 Antibodies)/POMC (show POMC Antibodies) axis and may influence body mass index.
these common variants in PCSK1 (show PCSK1 Antibodies) and POMC (show POMC Antibodies) were not the major cause of obesity in the Thai subjects sampled. However, variants in PCSK1 (show PCSK1 Antibodies) did affect cholesterol level, LDL-C level, and waist circumference.
ACTH (show POMC Antibodies) was readily detected at significantly higher levels in regions of ACTH (show POMC Antibodies)-secreting adenomas and in normal anterior adenohypophysis compared with non-secreting adenoma and neurohypophysis.
CSF (show CSF2 Antibodies) POMC (show POMC Antibodies) was higher in lean vs. overweight/obese subjects.
The association has been reported between polymorphisms of the CRH (show CRH Antibodies) and POMC (show POMC Antibodies) genes with economic traits in Korean cattle.
Expression of the hepatic endocannabinoid system and proopiomelanocortin (show POMC Antibodies) was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum.
Significant associations were observed between POMC (show POMC Antibodies) c.288C>T with start-of-finishing weight (SOF (show GJA1 Antibodies) WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA (show PHB2 Antibodies); P = 0.03) and marbling
The polymorphism of POMC (show POMC Antibodies) gene is associated with the growth traits of Nanyang cattle.
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
adrenal corticotropic hormone
, adrenocorticotropic hormone
, alpha-melanocyte stimulating hormone
, corticotropin-like intermediary peptide
, melanotropin gamma
, alpha-melanocyte-stimulating hormone
, beta-melanocyte-stimulating hormone
, lipotropin beta
, lipotropin gamma
, melanotropin alpha
, melanotropin beta
, opiomelanocortin prepropeptide
, proopiomelanocortin preproprotein
, beta-melanocyte stimulating hormone
, proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)