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beta Endorphin Products

(Endorphin beta (beta-EP))
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

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Featured beta Endorphin Categories

beta Endorphin Antibodies

High quality antibodies with extensive validation data.

beta Endorphin ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended beta Endorphin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN93907
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6995224
Quantity 200 μL
Datasheet Datasheet
Reactivity Mammalian
Application
Validations
Cat. No. ABIN285460
Quantity 250 μL
Datasheet Datasheet

Recommended beta Endorphin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6955552
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955553
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN454542
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our beta Endorphin products

van der Venne, Balint, Drews, Parzer, Resch, Koenig, Kaess: "Pain sensitivity and plasma beta-endorphin in adolescent non-suicidal self-injury." in: Journal of affective disorders, Vol. 278, pp. 199-208, (2021) (PubMed).

Blasco-Fontecilla, Herranz-Herrer, Ponte-Lopez, Gil-Benito, Donoso-Navarro, Hernandez-Alvarez, Gil-Ligero, Horrillo, Meana, Royuela, Rosado-Garcia, Sánchez-López: "Serum β-endorphin levels are associated with addiction to suicidal behavior: A pilot study." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 40, pp. 38-51, (2020) (PubMed).

García-Domínguez, Lastra, Folgueras, Cernuda-Cernuda, Fernández-García, Hidalgo, Menéndez, Baamonde: "The Chemokine CCL4 (MIP-1β) Evokes Antinociceptive Effects in Mice: a Role for CD4+ Lymphocytes and Met-Enkephalin." in: Molecular neurobiology, Vol. 56, Issue 3, pp. 1578-1595, (2019) (PubMed).

Lee, Lee, Lee, Kim: "Blood dopamine level enhanced by caffeine in men after treadmill running." in: The Chinese journal of physiology, Vol. 62, Issue 6, pp. 279-284, (2019) (PubMed).

Nuseir, Alzoubi, Alhusban, Bawaane, Al-Azzani, Khabour: "Sucrose and naltrexone prevent increased pain sensitivity and impaired long-term memory induced by repetitive neonatal noxious stimulation: Role of BDNF and β-endorphin." in: Physiology & behavior, Vol. 179, pp. 213-219, (2018) (PubMed).

Henrique, Gabrielloni, Rodney, Barbieri: "Non-pharmacological interventions during childbirth for pain relief, anxiety, and neuroendocrine stress parameters: A randomized controlled trial." in: International journal of nursing practice, Vol. 24, Issue 3, pp. e12642, (2018) (PubMed).

Olorunmoteni, Adeodu, Oseni, Obuotor: "Cerebrospinal fluid and plasma β-endorphin levels in children with cerebral malaria." in: Brain and behavior, Vol. 7, Issue 4, pp. e00673, (2017) (PubMed).

Poznanski, Lesniak, Korostynski, Szklarczyk, Lazarczyk, Religa, Bujalska-Zadrozny, Sadowski, Sacharczuk: "Delta-opioid receptor antagonism leads to excessive ethanol consumption in mice with enhanced activity of the endogenous opioid system." in: Neuropharmacology, Vol. 118, pp. 90-101, (2017) (PubMed).

Sechi, Di Cerbo, Canello, Guidetti, Chiavolelli, Fiore, Cocco: "Effects in dogs with behavioural disorders of a commercial nutraceutical diet on stress and neuroendocrine parameters." in: The Veterinary record, (2016) (PubMed).

Tang, Chai, Kang, Huang, Hou, Tang, Li: "I-gel Laryngeal Mask Airway Combined with Tracheal Intubation Attenuate Systemic Stress Response in Patients Undergoing Posterior Fossa Surgery." in: Mediators of inflammation, Vol. 2015, pp. 965925, (2016) (PubMed).

Synonyms and alternative names related to beta Endorphin

pro-opiomelanocortin-alpha (Pomc), proopiomelanocortin (POMC), ACTH, alpha-MSH, alphaMSH, BE, Beta-LPH, beta-MSH, Clip, CLIP, Gamma-LPH, gamma-MSH, LPH, MSH, Npp, NPP, POC, Pomc-1, Pomc1

Protein level used designations for beta Endorphin

  • adrenal corticotropic hormone
  • adrenocorticotropic hormone
  • alpha-melanocyte stimulating hormone
  • beta-endorphin
  • corticotropin-like intermediary peptide
  • corticotropin-lipotropin
  • melanotropin gamma
  • met-enkephalin
  • pro-opiomelanocortin
  • adrenocorticotropin
  • alpha-MSH
  • alpha-melanocyte-stimulating hormone
  • beta-LPH
  • beta-MSH
  • beta-melanocyte-stimulating hormone
  • gamma-LPH
  • gamma-MSH
  • lipotropin beta
  • lipotropin gamma
  • melanotropin alpha
  • melanotropin beta
  • opiomelanocortin prepropeptide
  • pro-ACTH-endorphin
  • proopiomelanocortin preproprotein
  • beta-lipotropin
  • beta-melanocyte stimulating hormone
  • proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)
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