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|Application / Reactivity||Human||Mouse (Murine)||Dog (Canine)||Pig (Porcine)||Rat (Rattus)|
|Western Blotting (WB)||62 Antibodies||25 Antibodies||6 Antibodies||5 Antibodies||19 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies||1 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||4 Antibodies||7 Antibodies||4 Antibodies||3 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||3 Antibodies||11 Antibodies||5 Antibodies||4 Antibodies||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||1 Antibodies||1 Antibodies|
|Antigen||CAP-GLY Domain Containing Linker Protein 1 (CLIP1) Antibodies|
|Reactivity||Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus) Alternatives|
|Conjugate||This CLIP1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|1 reference available|
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Product Details anti-CLIP1 AntibodyTarget Details CLIP1 Application Details Handling References for anti-CLIP1 Antibody (ABIN401523) Images
|Specificity||This antibody detects CLIP1 / Restin at C-term. It is expected to recognize both reported isoforms (NP_002947.1, NP_937883.1).|
|Cross-Reactivity (Details)||Species reactivity (expected):Mouse, Rat, Dog, PigSpecies reactivity (tested):Human.|
|Purification||Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide|
|Immunogen||Peptide from the C-Terminus of the protein sequence according to NP_002947.1, NP_937883.1 . Genename: CLIP1|
Target Details CLIP1Product Details anti-CLIP1 Antibody Application Details Handling References for anti-CLIP1 Antibody (ABIN401523) Images back to top
|Alternative Name||CLIP1 / Restin (CLIP1 Antibody Abstract)|
|Background||CLIP170 associates with the growing ends of microtubules, a type of behaviour known as 'plus end tracking' that is exhibited by proteins called +TIPS. It is known to bind to CLASPS and IQGAP1, and is thought to play a role as a positive regulator of microtubule dynamics. CLIP170 is also involved in targeting of the dynactin complex to the ends of growing microtubules, and may be important in mitosis.Synonyms: CAP-Gly domain-containing linker protein 1, CLIP-170, CYLN1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, RSN, Reed-Sternberg intermediate filament-associated protein|
Application DetailsProduct Details anti-CLIP1 Antibody Target Details CLIP1 Handling References for anti-CLIP1 Antibody (ABIN401523) Images back to top
Peptide ELISA: 1/8000. Western blot: Approx 160 kDa band observed in Human Breast Cancer lysates (calculatedMW of 160 kDa according to NP_002947.1. Recommended concentration: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: Human Thyroid Gland shows structuredcytoplasm staining in active epithelial cells. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CLIP1 Antibody Target Details CLIP1 Application Details References for anti-CLIP1 Antibody (ABIN401523) Images back to top
|Buffer||Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.|
References for anti-CLIP1 Antibody (ABIN401523)Product Details anti-CLIP1 Antibody Target Details CLIP1 Application Details Handling Images back to top
Tanenbaum, Macůrek, Galjart et al.: "Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly." in: The EMBO journal, Vol. 27, Issue 24, pp. 3235-45, 2008 (PubMed).
ImagesProduct Details anti-CLIP1 Antibody Target Details CLIP1 Application Details Handling References for anti-CLIP1 Antibody (ABIN401523) back to top