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anti-Mouse (Murine) Spastin antibody for Western Blotting

Recommended Spastin Antibody (supplied by: Log in to see )

Antigen
Spastin (SPAST) Antibodies
  • ADPSP
  • CG5977
  • D-spastin
  • Dmel\\CG5977
  • Dspastin
  • FSP2
  • LOC100224472
  • mKIAA1083
  • Spas
  • SPAST
  • Spg4
  • SPG4
  • spg4
  • zgc:85952
Epitope
C-Term
5
3
3
2
2
1
Reactivity
Mouse (Murine), Rat (Rattus), Human
20
3
3
1
Host
Rabbit
13
7
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
15
14
3
2
2
1
1
Supplier
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Catalog No. ABIN572141
$ 454.67
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011806369 ABIN3060310 WB Rabbit Log in to see Polyclonal

Similar anti-Spastin Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 17 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies
Immunohistochemistry (IHC) 4 Antibodies 3 Antibodies 3 Antibodies
Immunofluorescence (IF) 2 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
ELISA (Capture) 1 Antibodies
ELISA 15 Antibodies 2 Antibodies 2 Antibodies

General

Antigen Spastin (SPAST) Antibodies
Epitope C-Term
(5), (3), (3), (2), (2), (1)
Reactivity Mouse (Murine), Rat (Rattus), Human
(20), (3), (3), (1)
Host Rabbit
(13), (7)
Clonality
Polyclonal
Application Immunohistochemistry (IHC), Western Blotting (WB)
(15), (14), (3), (2), (2), (1), (1)
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Product Details anti-Spastin Antibody

Target Details Spastin Application Details Handling Images
Specificity Specific for Spastin.
Purification Whole serum
Immunogen A synthetic peptide fromc-terminal region of mouse Spastin (Spastic paraplegia 4 protein) conjugated to an immunogenic carrier protein was used as the antigen.

Target Details Spastin

Product Details anti-Spastin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Spastin (SPAST Antibody Abstract)
Background ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
Subcellular location: Membrane, Single-pass membrane protein. Cytoplasm › cytoskeleton › centrosome. Cytoplasm › cytoskeleton. Cytoplasm › perinuclear region. Endoplasmic reticulum. Endosome. Nucleus. Cytoplasm › cytoskeleton › spindle. Note: Localization to the centrosome is independent of microtubules. Localizes to the midbody of dividing cells, and this requires CHMP1B. Enriched in the distal axons and branches of postmitotic neurons. Isoform 3 is the main endosomal form.
Tissue specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. The short isoforms may predominate in brain and spinal cord. Also known as: SPAST, Spastic paraplegia 4 protein, ADPSP, FSP2, SPG4.
Research Area Signaling, Metabolism, Cytoskeleton
Pathways Microtubule Dynamics

Application Details

Product Details anti-Spastin Antibody Target Details Spastin Handling Images back to top
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only

Handling

Product Details anti-Spastin Antibody Target Details Spastin Application Details Images back to top
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months