anti-Rat (Rattus) CXCR7 antibody for Enzyme Immunoassay

Recommended CXCR7 Antibody (supplied by: Log in to see )

Antigen
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • G protein coupled receptor
  • atypical chemokine receptor 3
  • chemokine (C-X-C motif) receptor 7
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
  • Cxcr7
  • CXCR7
Epitope
N-Term
46
26
26
15
13
11
11
11
9
6
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
202
108
79
7
7
6
6
4
4
4
4
3
1
1
1
1
1
1
1
Host
Rabbit
132
82
19
5
1
Clonality
Polyclonal
Conjugate
This CXCR7 antibody is un-conjugated
14
12
10
10
10
10
9
9
8
8
7
7
6
4
4
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
131
97
54
41
26
25
16
7
5
3
3
2
2
1
Supplier
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Catalog No. ABIN492896
$ 456.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN615865 EIA IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-CXCR7 antibody for Enzyme Immunoassay

Similar anti-CXCR7 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 18 Antibodies 25 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Flow Cytometry (FACS) 24 Antibodies 42 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 4 Antibodies
Immunofluorescence (IF) 11 Antibodies 13 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Simple Western (SimWes) 2 Antibodies
Western Blotting (WB) 35 Antibodies

General

Antigen Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
Epitope N-Term
(46), (26), (26), (15), (13), (11), (11), (11), (9), (6), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(202), (108), (79), (7), (7), (6), (6), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(132), (82), (19), (5), (1)
Clonality
Polyclonal
Conjugate This CXCR7 antibody is un-conjugated
(14), (12), (10), (10), (10), (10), (9), (9), (8), (8), (7), (7), (6), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(131), (97), (54), (41), (26), (25), (16), (7), (5), (3), (3), (2), (2), (1)
Pubmed 4 references available
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Product Details anti-CXCR7 Antibody

Target Details CXCR7 Application Details Handling ProductDetails: References for anti-CXCR7 antibody (ABIN492896) Images
Specificity This antibody detects a single 52-53 kDa CXCR7.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography
Immunogen Synthetic peptide (selective for CXCR7 receptor N-terminal region)

Target Details CXCR7

Product Details anti-CXCR7 Antibody Application Details Handling ProductDetails: References for anti-CXCR7 antibody (ABIN492896) Images back to top
Antigen
Alternative Name CXCR7 / GPR159 (CXCR7 Antibody Abstract)
Background Chemokine (Chemoattractant Cytokines) are small peptides that are potent activators and chemo-attractants for leukocyte subpopulations and other non-hemopoietic cells. Chemokine receptors (CXCR) belong to the super-family of G protein-coupled receptors (GPCR), which regulate the trafficking and activation of leukocytes, and operate as co-receptors in the entry of HIV-1 and proliferation and migration of immature neurons, glia and their precursors (1). Furthermore, chemokine receptors participate in the etiology and progression of various brain disorders, including AIDS dementia, neuro-inflammatory disease and neuroplasia, making them important potential therapeutic targets in these cases Several subtypes of CXCR have been characterized. Activation of naive T cells by specific antigen and cytokines, up-regulate cell adhesion molecules (CAM) as well as chemokine receptors on their surface, which directs them to migrate towards the inflamed tissues. Chemokine receptor type 3 (CXCR3) is induced during T cell activation and CXCR3 positive cell are enriched at the inflammatory site (2). On the contrary, glucocorticoid dexamethasone has potent anti-inflammatory effects, yet it up-regulates expression of CXCR4 but not that of CXCR1 and CXCR3 (4). The chemokine receptor 7 protein is approximately 43-44 kDa (378 amino acids) protein which has 7 transmembrane domains, characteristic of G-protein coupled receptors. The all CXCR sequence analyses suggest the presence of 7 transmembrane domains, a characteristic feature of GPCR. The protein has putative N-glycosylation sites near the extra cellular N-terminal end of the proteins. The protein has a large 3rd intra cellular loop which interacts with G-proteins. The short carboxy terminal is intracellular and has putative post-translational sites. The Anti-CXCR-selective antibodies were generated against conserved but unique sequences on various CXCR receptors that are expressed only in a particular CXCR receptor subtype.Synonyms: C-X-C chemokine receptor type 7, CMKOR1, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, GPR-159, RDC1
Gene ID 57007
NCBI Accession NP_064707
UniProt P25106
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-CXCR7 Antibody Target Details CXCR7 Handling ProductDetails: References for anti-CXCR7 antibody (ABIN492896) Images back to top
Application Notes Immunohistochemistry on frozen sections. Western blot: 1: 500. ELISA. IMM and i. p pull-down assays: > 1: 250.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details ProductDetails: References for anti-CXCR7 antibody (ABIN492896) Images back to top
Concentration 0.685 - 1.25 mg/mL
Buffer Stabilization buffer with preservative
Preservative Other preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.

ProductDetails: References for anti-CXCR7 antibody (ABIN492896)

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details Handling Images back to top
Background publications

Tran, Miller: "Chemokine receptors: signposts to brain development and disease." in: Nature reviews. Neuroscience, Vol. 4, Issue 6, pp. 444-55, 2003

Xie, Nomura, Lu, Chen, Koch, Weng, Rosa, Di Salvo, Mudgett, Peterson, Wicker, DeMartino: "Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation." in: Journal of leukocyte biology, Vol. 73, Issue 6, pp. 771-80, 2003

Segerer: "The role of chemokines and chemokine receptors in progressive renal diseases." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 41, Issue 3 Suppl 1, pp. S15-8, 2003

Ramjeesingh, Leung, Siu: "Interleukin-8 secreted by endothelial cells induces chemotaxis of melanoma cells through the chemokine receptor CXCR1." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1292-4, 2003