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Browse our anti-G Protein-Coupled Receptor Kinase 5 (GRK5) Antibodies

Full name:
anti-G Protein-Coupled Receptor Kinase 5 Antibodies (GRK5)
On www.antibodies-online.com are 110 G Protein-Coupled Receptor Kinase 5 (GRK5) Antibodies from 23 different suppliers available. Additionally we are shipping G Protein-Coupled Receptor Kinase 5 Proteins (12) and G Protein-Coupled Receptor Kinase 5 Kits (4) and many more products for this protein. A total of 133 G Protein-Coupled Receptor Kinase 5 products are currently listed.
Synonyms:
DKFZp468J1119, Gprk5, GRK5, si:dkey-171l20.1, zgc:153020

Most Popular Reactivities for anti-G Protein-Coupled Receptor Kinase 5 (GRK5) Antibodies

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All available anti-G Protein-Coupled Receptor Kinase 5 Antibodies

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Top referenced anti-G Protein-Coupled Receptor Kinase 5 Antibodies

  1. Human Polyclonal GRK5 Primary Antibody for EIA, IHC (p) - ABIN359046 : Pronin, Morris, Surguchov, Benovic: Synucleins are a novel class of substrates for G protein-coupled receptor kinases. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN359046

  2. Cow (Bovine) Polyclonal GRK5 Primary Antibody for IHC, WB - ABIN2785866 : Liggett, Cresci, Kelly, Syed, Matkovich, Hahn, Diwan, Martini, Sparks, Parekh, Spertus, Koch, Kardia, Dorn: A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. in Nature medicine 2008 (PubMed)

More Antibodies against G Protein-Coupled Receptor Kinase 5 Interaction Partners

Zebrafish G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. GRK2 (show ADRBK1 Antibodies) and GRK5 control cardiac function as well as morphogenesis during development although with different morphological outcomes.

  2. Results identify GRK5/6 as novel kinases for the single transmembrane receptor LRP6 (show LRP5 Antibodies) during Wnt (show WNT2 Antibodies) signaling.

Human G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. Candidate gene eQTL (show EQTN Antibodies) showed a trans-acting association between variants of G protein-coupled receptor kinase 5 gene (show GPD1 Antibodies), previously linked to altered BB response, and high expression of VOPP1 (show VOPP1 Antibodies).

  2. Further, we will also present potential therapeutic strategies (i.e. small molecule inhibition, gene therapy) that may have potential in combating the deleterious effects of GRK5 in heart failure.

  3. Suggest a common regulatory pattern for the beta(1)-AR/GRK5 which is independent of cellular type or pathology.

  4. We demonstrated that the SNPs and the related haplotypes of GRK5 could play a central role in predisposing Parkinson disease patients to cognitive impairment.

  5. Thus, we provided new insight into the function of GRKs in agonist-unstimulated GPCR (show NMUR1 Antibodies) trafficking using a recombinant AM1 receptor and further determined the region of the CLR C-tail responsible for this GRK (show GRK4 Antibodies) function.

  6. ADORA2A (show ADORA2A Antibodies) and GRK5 gene variants may influence the etiology of malaria infection.

  7. A significant difference in the frequency of GRK5 polymorphism was found between Takotsubo cardiomyopathy patients and controls, supporting a genetic predisposition to this cardiac syndrome.

  8. Specific patterns of altered heart GRK5 gene expression were found in models of cardiac hypertrophy.

  9. This study sought to identify the distributed characteristics of these variant genotypes in Chinese population, and influence of GRK5 and ADRB1 (show ADRB1 Antibodies) polymorphisms on systolic heart failure morbidity.

  10. GRK5 is found in a partially closed state with its kinase domain C-tail forming novel interactions with nucleotide and the N-lobe (show LTF Antibodies).

Mouse (Murine) G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. Overall, these data suggest that GRK5 negatively regulates CXCL1/KC (show CXCL1 Antibodies) levels during bacterial pneumonia but that the role of GRK5 in the clinical outcome in this model is dependent on the bacterial dose.

  2. Generated mice with genetic knockout (KO) of the G protein-coupled receptor kinase (GRK) 5 gene (show GPD1 Antibodies) by microinjection of TALEN mRNA. TALEN vectors were designed to target exons 1, 3, and 5 of the mouse GRK5 gene.

  3. These results of this study suggest that GRK5 deficiency indeed makes the mice more susceptible to wide range of behavioral impairments, including cognitive impairments.

  4. MOR (show OPRM1 Antibodies) phosphorylation is regulated by agonist-selective recruitment of distinct GRK (show GRK4 Antibodies) isoforms that influence different opioid-related behaviors. Modulation of GRK5 function could serve as a new approach for preventing addiction to opioids.

  5. GRK5, acting in a kinase independent manner, is a facilitator of NFAT (show NFATC1 Antibodies) activity and part of a DNA-binding complex responsible for pathological hypertrophic gene transcription.

  6. influence of GRK5 on NF-kappaB (show NFKB1 Antibodies) expression and activity

  7. these data identified GRK5 as a positive regulator of insulin (show INS Antibodies) sensitivity.

  8. metoprolol is a biased ligand that selectively activates a G protein-independent and GRK5/beta-arrestin2 (show ARRB2 Antibodies)-dependent pathway, and induces cardiac fibrosis.

  9. These results define myocyte GRK5 as a critical regulator of pathological cardiac growth after ventricular pressure overload, supporting its role as an endogenous (patho)-physiological HDAC (show HDAC3 Antibodies) kinase.

  10. these results suggest that GRK5 is an important regulator of adipogenesis and is crucial for the development of diet-induced obesity.

Cow (Bovine) G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. GRK5, acting in a kinase independent manner, is a facilitator of NFAT (show NFATC1 Antibodies) activity and part of a DNA-binding complex responsible for pathological hypertrophic gene transcription.

  2. potential GRK5 interacting proteins and the association of GRK5 with DDB1 in cell and the regulation of GRK5 level by DDB1-CUL4 ubiquitin ligase complex-dependent proteolysis pathway

  3. GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.

G Protein-Coupled Receptor Kinase 5 (GRK5) Antigen Profile

Antigen Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).

Alternative names and synonyms associated with G Protein-Coupled Receptor Kinase 5 (GRK5)

  • G protein-coupled receptor kinase 5 (GRK5) antibody
  • G protein-coupled receptor kinase 5 (grk5) antibody
  • G protein-coupled receptor kinase 4 (grk4) antibody
  • G protein-coupled receptor kinase 5 (Grk5) antibody
  • DKFZp468J1119 antibody
  • Gprk5 antibody
  • GRK5 antibody
  • si:dkey-171l20.1 antibody
  • zgc:153020 antibody

Protein level used designations for GRK5

G protein-coupled receptor kinase 5 , GRK5 , FP2025 , g protein-coupled receptor kinase GRK5

GENE ID SPECIES
100065919 Equus caballus
550070 Xenopus (Silurana) tropicalis
560806 Danio rerio
100171722 Pongo abelii
100593251 Nomascus leucogenys
560761 Danio rerio
2869 Homo sapiens
14773 Mus musculus
59075 Rattus norvegicus
281801 Bos taurus
423929 Gallus gallus
486915 Canis lupus familiaris
100152937 Sus scrofa
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