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Browse our Pim-3 Oncogene Proteins (PIM3)

Full name:
Pim-3 Oncogene Proteins (PIM3)
On www.antibodies-online.com are 11 Pim-3 Oncogene (PIM3) Proteins from 7 different suppliers available. Additionally we are shipping Pim-3 Oncogene Antibodies (29) and Pim-3 Oncogene Kits (13) and many more products for this protein. A total of 55 Pim-3 Oncogene products are currently listed.
Synonyms:
BC026639, Kid1, pim-3, pim1-a
list all proteins Gene Name GeneID UniProt
PIM3 415116 Q86V86
PIM3 64534 O70444
PIM3 223775 P58750

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Pim-3 Oncogene Proteins (PIM3) by Origin

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More Proteins for Pim-3 Oncogene Interaction Partners

Human Pim-3 Oncogene (PIM3) interaction partners

  1. The expression status of Pim-3 mRNA was significantly associated with pathological parameters such as pre-surgery prostate specific antigen (show KLK3 Proteins), Gleason score, pathological stage, and lymphoid metastasis.

  2. Pim-3 expression was inversely correlated with that of miR (show MLXIP Proteins)-377.

  3. SSRP1 (show SSRP1 Proteins)/Ets-1 (show ETS1 Proteins)/Pim-3 signalling is tightly associated with the proliferation, apoptosis, autophagy, invasion and clonogenicity of nasopharyngeal carcinoma cells, and blockage of this signalling facilitates chemosensitivity of the cells to docetaxel.

  4. Pim-3 expression showed a positive correlation with tumor cell differentiation.

  5. Pim-3 has a role in human pancreatic cancer cell survival against radiation

  6. A high percentage of urothelial carcinomas express Pim (show PIM1 Proteins) kinases. Pim (show PIM1 Proteins) expression differs in NILG, NIHG, and IHG lesions.

  7. MicroRNA506 participates in pancreatic cancer pathogenesis by targeting PIM3

  8. Pim-3 kinase enhances growth and metastatic properties of prostate cancer xenografts. PC-3 (show PCSK1 Proteins) prostate cancer cells overexpressing either Pim-1 (show PIM1 Proteins) or Pim-3 kinases form larger xenograft tumors than the parental PC-3 (show PCSK1 Proteins) cells.

  9. Knockdown of Pim-3 by specific shRNA slowed decreased proliferation, induced cell cycle arrest in the G0/G1 phase, and increased apoptosis in glioblastoma cells.

  10. PIM3 expression is higher in ovarian cancer than in normal ovarian tissue. Upregulation of PIM3 promotes proliferation and migration of ovarian cancer cells.

Mouse (Murine) Pim-3 Oncogene (PIM3) interaction partners

  1. Loss of PIM3 is associated with abnormal hematopoietic phenotypes.

  2. investigation of physiological role of Pim3 in beta-cell function: regulates glucose-stimulated insulin (show INS Proteins) secretion; limits ERK (show EPHB2 Proteins) signaling; interacts with SOCS6 (show SOCS6 Proteins); Pim3 localized to beta-cell; Pim3 knockout mice display increased glucose tolerance

  3. Pim-3 has an important role in modulating c-Myc and PGC-1alpha protein levels and cell growth

  4. All three Pim (show PIM1 Proteins) kinase family members predominantly phosphorylate Bad on Ser112 and in addition are capable of phosphorylating Bad on multiple sites associated with the inhibition of the pro-apoptotic function of Bad in HEK (show EPHA3 Proteins)-293 cells

  5. Pim-3 kinase has a novel role in the control of self-renewal of embryonic stem cells.

  6. Pim-3 is expressed in endothelial cells and promotes vascular tube formation.

Pim-3 Oncogene (PIM3) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.

Alternative names and synonyms associated with Pim-3 Oncogene (PIM3)

  • Serine/threonine-protein kinase Pim-3 (pim3)
  • pim-1 oncogene (pim3)
  • pim-3 oncogene (PIM3)
  • pim-3 oncogene (Pim3)
  • proviral integration site 3 (Pim3)
  • BC026639 protein
  • Kid1 protein
  • pim-3 protein
  • pim1-a protein

Protein level used designations for Pim-3 Oncogene Proteins (PIM3)

serine/threonine protein kinase pim-3 , non-specific serine/threonine protein kinase , serine/threonine-protein kinase pim-3 , serine/threonine kinase Pim-3 , kinase induced by depolarization , protein kinase Kid-1 , proviral integration site 3 , serine threonine kinase pim3 , KID-1/kinase induced by depolarization

GENE ID SPECIES
100194838 Salmo salar
394343 Xenopus laevis
415116 Homo sapiens
64534 Rattus norvegicus
768655 Gallus gallus
100336651 Bos taurus
100722030 Cavia porcellus
223775 Mus musculus
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