Browse our anti-AKT (AKT1) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Antibodies (AKT1)
On www.antibodies-online.com are 1197 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antibodies from 46 different suppliers available. Additionally we are shipping AKT Kits (56) and AKT Proteins (46) and many more products for this protein. A total of 1398 AKT products are currently listed.
Synonyms:
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

All available anti-AKT Antibodies

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Top referenced anti-AKT Antibodies

  1. Human Polyclonal AKT Primary Antibody for EIA, IHC (p) - ABIN358075 : Bellacosa, Chan, Ahmed, Datta, Malstrom, Stokoe, McCormick, Feng, Tsichlis: Akt activation by growth factors is a multiple-step process: the role of the PH domain. in Oncogene 1998 (PubMed)
    Show all 4 references for 358075

  2. Human Polyclonal AKT Primary Antibody for DB - ABIN389509 : DeBusk, Hallahan, Lin: Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway. in Experimental cell research 2004 (PubMed)
    Show all 4 references for 389509

  3. Human Polyclonal AKT Primary Antibody for FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for 652283

  4. Human Polyclonal AKT Primary Antibody for WB - ABIN389510 : Bourguignon, Singleton, Diedrich et al.: Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte ... in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for 389510

  5. Human Polyclonal AKT Primary Antibody for IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Show all 3 references for 725195

  6. Cow (Bovine) Polyclonal AKT Primary Antibody for WB - ABIN2792187 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

  7. Human Polyclonal AKT Primary Antibody for FACS, IF - ABIN655915 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

More Antibodies against AKT Interaction Partners

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. The metabolic defects of cycG (show CCNG1 Antibodies) mutant animals are abrogated by a concomitant loss of Wdb, CycG (show CCNG1 Antibodies) presumably influences Akt1 activity at the PP2A (show PPP2R2B Antibodies) nexus; Well rounded (Wrd), another B' subunit of PP2A (show PPP2R2B Antibodies) in Drosophila, binds CycG (show CCNG1 Antibodies) similar to Wdb, and that its loss ameliorates some, but not all, of the metabolic defects of cycG (show CCNG1 Antibodies) mutants.

  2. Our findings demonstrated that lovastatin restored LRRK2 (show LRRK2 Antibodies)-G2019S neurite degeneration by augmenting Akt/NRF2 (show NFE2L2 Antibodies) pathway and inhibiting downstream GSK3b (show GSK3b Antibodies) activity, which decreased phospho-tau levels. We suggested that lovastatin is a potential disease-modifying agent for LRRK2 (show LRRK2 Antibodies)-G2019S parkinsonism.

  3. subtle manipulation of foxo (show FOXO Antibodies) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  4. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  5. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  6. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  7. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (show GRIN1 Antibodies) localization, and postsynaptic membrane elaboration

  8. Tsc2 (show TSC2 Antibodies) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (show TSC2 Antibodies) mutants, leading to the hypothesis that Tsc2 (show TSC2 Antibodies) and Akt might work via the same genetic pathway to regulate synapse growth.

  9. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  10. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (show PTEN Antibodies) and microRNA bantam.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. CIPK23 and AtKC1 exhibit distinct effects; however, they act synergistically and balance K(+) uptake/leakage to modulate AKT1-mediated low potassium responses in Arabidopsis.

  2. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (show FNTA Antibodies), which further represses the activity of K(+) channel (show KCNC4 Antibodies) AKT1 in Arabidopsis.

  3. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  4. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  5. These findings provide further insights into the signaling network consisting of CBL (show CBL Antibodies)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  6. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  7. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  8. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  9. CIPK23 directly phosphorylates the K+ transporter AKT1

  10. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (show CA2 Antibodies)+)-dependent manner, connecting the Ca(2 (show CA2 Antibodies)+) signal to K(+) uptake through activation of a K(+) channel (show KCNC4 Antibodies).

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. Furthermore, Leishmania RNA virus 1-induced TLR-3 (show TLR3 Antibodies) activation promoted parasite persistence by enhancing macrophage survival through Akt activation in a manner partially dependent on miR (show MLXIP Antibodies)-155.

  2. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (show CCL2 Antibodies) proliferation, and was associated with inhibition of PI3K/Akt signaling pathway through activation of GPR120 (show O3FAR1 Antibodies).

  3. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (show ROS1 Antibodies)) generation, RhoA (show RHOA Antibodies) activity and normalizing Akt/GSK3beta (show GSK3b Antibodies) signaling pathways.

  4. This review summarises and discusses the consequences of genetic deletions of Akt isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 and Akt2 (show AKT2 Antibodies) rapidly induced mortality, hepatic Akt inhibition induced liver injury that promotes hepatocellular carcinoma.

  5. B cell leukemia-induced inhibition of T cell Akt/mTORC1 signaling and glucose metabolism drives T cell dysfunction.

  6. Data indicate that chlorogenic acid (CGA (show CGA Antibodies)) protected osteoblast MC3T3-E1 cells against oxidative damage via PI3K/Akt-mediated activation of Nrf2 (show NFE2L2 Antibodies)/HO-1 (show HMOX1 Antibodies) pathway, which may be an effective drug in treatment of osteoporosis.

  7. It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor (show FGFR2 Antibodies) 2, in the oligodendr

  8. endothelial-barrier protective role of VEGF (show VEGFA Antibodies) in the long term and the importance of Akt1-FoxO (show FOXO3 Antibodies) signaling on tight-junction stabilization and prevention of vascular leakage through claudin expression, is reported.

  9. these results indicate that PI3K and Akt ( Akt1-Akt3 (show AKT3 Antibodies))play distinct roles, and that PI3K stimulates Akt-independent pathways that are important for GLUT4 (show SLC2A4 Antibodies) translocation.

  10. Data show that macrophage M2 polarization was mediated through PTEN (show PTEN Antibodies)/PI3k/AKT pathway activation.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. Report expression of microRNAs in lung neoplasms with increased AKt1/2 gene number.

  2. Integrin beta1 appears to serve as a partner of Stathmin (show STMN1 Antibodies) induction of ERK (show EPHB2 Antibodies) and Akt signaling by inhibiting apoptosis in the cholangiocarcinoma cell.

  3. Taken together, MREG (show MREG Antibodies) regulates thyroid cancer cell invasion and proliferation through PI3K (show PIK3CA Antibodies)/Akt-mTOR (show FRAP1 Antibodies) signaling pathway. MREG (show MREG Antibodies) may serve as a promising therapeutic strategy for thyroid cancer.

  4. This review summarises and discusses the consequences of genetic deletions of Akt isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 and Akt2 (show AKT2 Antibodies) rapidly induced mortality, hepatic Akt inhibition induced liver injury that promotes hepatocellular carcinoma.

  5. T cells from patients with acute or chronic B cell leukemia, which were also metabolically exhausted had defective Akt/mTORC1 signaling, reduced expression of Glut1 (show SLC2A1 Antibodies) and hexokinase 2 (show HK2 Antibodies), and decreased glucose metabolism.

  6. Disruption of CK1alpha (show CSNK1A1 Antibodies) function in myeloma cells resulted in decreased Mdm2 (show MDM2 Antibodies), increased p53 (show TP53 Antibodies) and p21 (show CDKN1A Antibodies) and reduced expression of beta-catenin (show CTNNB1 Antibodies) and AKT.

  7. Two different mechanisms: acquired radioresistance of surviving tumor cells after RT and intrinsic radioresistance of CSC are associated with tumor radioresistance. Inhibition of the AKT pathway results in radiosensitization of both types of tumor radioresistance. [review]

  8. Here, using PET with [(11)C]raclopride, we identified in the AKT1 gene a new variable number tandem repeat (VNTR) marker associated with baseline striatal dopamine D2/D3 receptor (show DRD3 Antibodies) availability and with methylphenidate-induced striatal dopamine increases in healthy volunteers.

  9. CD133 facilitates cancer stem cell-like properties by stabilizing EGFR (show EGFR Antibodies)-AKT signaling in HCC (show FAM126A Antibodies).

  10. These findings indicated that miR (show MLXIP Antibodies)-126 protects HCMECs from H/R-induced injury and inflammatory response by activating the PI3K (show PIK3CA Antibodies)/Akt/ eNOS (show NOS3 Antibodies) signaling pathway.

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR (show FRAP1 Antibodies)-FOXO1 (show FOXO1 Antibodies) signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 (show NOD2 Antibodies) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (show LRP2 Antibodies) is the sensor that determines whether cells will be protected or injured by albumin (show ALB Antibodies); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (show CTNNB1 Antibodies) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (show CAV1 Antibodies) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (show TGM2 Antibodies) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (show GSK3b Antibodies), and NF-kappaB (show NFKB1 Antibodies).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (show NOX1 Antibodies), reactive oxygen species, and PI3-kinase (show PIK3CA Antibodies) in stimulated NO release.

  6. PI3K/Akt and p53 (show TP53 Antibodies) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (show FRAP1 Antibodies), p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  8. Gab1 (show GAB1 Antibodies) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (show NOS3 Antibodies) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (show NOS3 Antibodies) phosphorylation and suppresses tumor necrosis factor alpha (show TNF Antibodies)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR (show FRAP1 Antibodies) and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT-independent manner

AKT (AKT1) Antigen Profile

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) antibody
  • CG4006 gene product from transcript CG4006-RA (Akt1) antibody
  • potassium channel AKT1 (KT1) antibody
  • thymoma viral proto-oncogene 1 (Akt1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) antibody
  • akt antibody
  • akt-1 antibody
  • Akt/PKB antibody
  • akt1 antibody
  • ATAKT1 antibody
  • CG4006 antibody
  • CWS6 antibody
  • D-Akt antibody
  • dakt antibody
  • dAKT/dPKB antibody
  • dAkt/PKB antibody
  • dakt1 antibody
  • DAKT1/PKB antibody
  • Dmel\\CG4006 antibody
  • dPKB antibody
  • DRAC-PK antibody
  • DRAC-PK66 antibody
  • DRAC-PK85 antibody
  • F18A8.2 antibody
  • F18A8_2 antibody
  • K+ transporter 1 antibody
  • l(3)04226 antibody
  • l(3)89Bq antibody
  • p-Akt antibody
  • pAkt antibody
  • PKB antibody
  • PKB-ALPHA antibody
  • PKB/Akt antibody
  • PKB/dAKT antibody
  • PKBalpha antibody
  • POTASSIUM TRANSPORTER antibody
  • PRKBA antibody
  • Rac antibody
  • RAC-ALPHA antibody
  • RacPK antibody
  • v-akt antibody
  • v-akt1 antibody
  • xAct antibody

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

GENE ID SPECIES
100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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