Browse our ARHGEF1 (ARHGEF1) ELISA Kits

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rho Guanine Nucleotide Exchange Factor (GEF) 1 ELISA Kits (ARHGEF1)
On are 3 rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) ELISA Kits from 1 different suppliers available. Additionally we are shipping ARHGEF1 Antibodies (60) and ARHGEF1 Proteins (5) and many more products for this protein. A total of 76 ARHGEF1 products are currently listed.
ARHGEF1, cb473, GEF1, Lbcl2, Lsc, P115-RHOGEF, SUB1.5, zgc:158261
list all ELISA KIts Gene Name GeneID UniProt
ARHGEF1 9138 Q92888
ARHGEF1 16801 Q61210
ARHGEF1 60323  

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More ELISA Kits for ARHGEF1 Interaction Partners

Human rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) interaction partners

  1. Data suggest that MCP1/CCL2 (show CCL2 ELISA Kits) induces activation/tyrosine phosphorylation of ARHGEF1/p115-RhoGEF and up-regulates RAC1 signaling in vascular smooth muscle cells (VSMCs); ARHGEF1 inhibition suppresses MCP1 (show CCL2 ELISA Kits)-induced VSMC migration and proliferation. (ARHGEF1 = Rho guanine nucleotide exchange factor 1; RAC1 = Rac (show AKT1 ELISA Kits) family small GTPase (show RACGAP1 ELISA Kits) 1; CCL2 (show CCL2 ELISA Kits) = C-C motif chemokine ligand 2 (show CXCL2 ELISA Kits))

  2. Data indicate that the crystal structure of PDZ-RhoGEF (show ARHGEF11 ELISA Kits) PDZ domain (show INADL ELISA Kits) in complex with the CXC chemokine receptor (show CXCR4 ELISA Kits) 2 (CXCR2 (show CXCR2 ELISA Kits)) C-terminal PDZ (show INADL ELISA Kits) binding motif.

  3. We have reported here for the first time a reduced activity of both Rac1 and Cdc42 (show CDC42 ELISA Kits) in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1, ARHGEF1, and ARHGAP36 (show ARHGAP36 ELISA Kits)

  4. contactin-1 (show CNTN1 ELISA Kits) displayed the ability to phosphorylate the RhoA (show RHOA ELISA Kits) activator p115 RhoGEF

  5. The novel role for p115RhoGEF in regulation of epithelial plasticity is dependent on Rho-DRF (show MPO ELISA Kits) signaling module.

  6. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).

  7. Modification of p115RhoGEF at Serine(330) regulates its RhoGEF (show ARHGEF11 ELISA Kits) activity.

  8. The action of DOCK7 in vivo may involve the coordinated integration of Cdc42/Rac1 signaling in the context of the membrane recruitment of a DOCK7 guanine nucleotide exchange factor (GEF) complex.

  9. High GEF1 expression is associated with metastasis of pancreatic cancer.

  10. Activation of p115-RhoGEF requires direct association of Galpha13 and the Dbl homology domain.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) interaction partners

  1. these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics.

  2. Upon beta(2)AR activation, both betaArrestin2 and p115RhoGEF translocate to the plasma membrane, with concomitant activation of RhoA (show RHOA ELISA Kits) and formation of focal adhesions and stress fibers.

  3. Thromboxane receptor (show TBXA2R ELISA Kits) signaling is required for fibronectin (show FN1 ELISA Kits)-induced matrix metalloproteinase 9 (show MMP9 ELISA Kits) production by human and murine macrophages and is attenuated by the Arhgef1 molecule.

  4. Results show that PKC-alpha phosphorylation of p115RhoGEF mediates TNF-alpha signaling to RhoA, and that this plays a critical role in signaling F-actin rearrangement and barrier dysfunction in endothelial cells.

  5. lsc/p115 (show ARHGAP4 ELISA Kits) deficiency results in impaired neuronal innervation and in motor dysfunction recapitulating several aspects of esophageal achalasia.

  6. These data demonstrate that Arhgef1 regulates alpha5beta1-mediated MMP expression by macrophages and that loss of Arhgef1 by leukocytes leads to pulmonary pathology.

  7. results show that control of RhoA (show RHOA ELISA Kits) signaling through Arhgef1 is central to the development of angiotensin II-dependent hypertension and identify Arhgef1 as a potential target for the treatment of hypertension

  8. First, Lsc homo-oligomerizes and is negatively regulated through domains in its C terminus; and second, functionally distinct isoforms of Lsc lacking these domains are present in the spleen.

  9. Lsc is essential for mediating TXA(2 (show TBXA2R ELISA Kits) )signaling involved in apoptosis and actin organization and suggest that TXA(2 (show TBXA2R ELISA Kits)) regulates thymic cellularity via Lsc.

  10. Lsc is a RhoA guanine nucleotide exchange factor that binds the heterotrimeric G-protein alpha-subunits, Galpha12 and Galpha13.

ARHGEF1 Antigen Profile

Antigen Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Alternative names and synonyms associated with ARHGEF1

  • Rho guanine nucleotide exchange factor (GEF) 1a (arhgef1a) Elisa Kit
  • Rho guanine nucleotide exchange factor (GEF) 1 (ARHGEF1) Elisa Kit
  • Rho guanine nucleotide exchange factor (GEF) 1 (arhgef1) Elisa Kit
  • Rho guanine nucleotide exchange factor (GEF) 1 (Arhgef1) Elisa Kit
  • ARHGEF1 Elisa Kit
  • cb473 Elisa Kit
  • GEF1 Elisa Kit
  • Lbcl2 Elisa Kit
  • Lsc Elisa Kit
  • P115-RHOGEF Elisa Kit
  • SUB1.5 Elisa Kit
  • zgc:158261 Elisa Kit

Protein level used designations for ARHGEF1

rho guanine nucleotide exchange factor (GEF) 1 , Rho guanine nucleotide exchange factor (GEF) 1 , rho guanine nucleotide exchange factor 1-like , 115 kDa guanine nucleotide exchange factor , 115-kD protein , Lsc homolog , p115RhoGEF , rho guanine nucleotide exchange factor 1 , lbc's second cousin , lymphoid blast crisis like 2 , lymphoid blast crisis-like 2

368266 Danio rerio
513377 Bos taurus
722198 Macaca mulatta
100037905 Xenopus (Silurana) tropicalis
100477081 Ailuropoda melanoleuca
100581841 Nomascus leucogenys
9138 Homo sapiens
16801 Mus musculus
60323 Rattus norvegicus
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