anti-Mouse (Murine) IKBKB antibody for Dot Blot

Recommended IKBKB Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
  • ikk-beta
  • ikk2
  • ikkb
  • ikkbeta
  • IKBKB
  • IKKB
  • CG4201
  • DIK
  • DLAK
  • DmIKK
  • DmIKKBeta
  • DmIKKb
  • DmIKKbeta
  • DmIkkbeta
  • Dmel\\CG4201
  • Dmikkb
  • Dmikkbeta
  • IK
  • IKK
  • IKK-beta
  • IKKb
  • IKKbeta
  • IRD-5
  • IRD5
  • Ik
  • Ikkb
  • Ikkbeta
  • Ird-5
  • Ird5
  • LRK
  • Lak
  • anon-89Bd
  • dIKK
  • dIKK-beta
  • dIKKbeta
  • dLak
  • dmIKKbeta
  • ikk
  • ird
  • ird5/DmIkk[beta]
  • IKK2
  • NFKBIKB
  • AIM-1
  • AI132552
  • IKK-2
  • IKK[b]
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • immune response deficient 5
  • inhibitor of kappaB kinase beta
  • ikbkb
  • IKBKB
  • ird5
  • Ikbkb
Epitope
pSer701
59
33
29
23
21
21
20
20
20
20
20
20
19
19
19
19
19
17
17
17
15
8
8
7
7
7
6
6
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
689
229
161
22
13
7
7
6
5
4
1
1
Host
Rabbit
581
121
9
2
Clonality
Polyclonal
Conjugate
This IKBKB antibody is un-conjugated
38
37
37
33
31
31
9
7
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Dot Blot (DB)
329
306
263
107
81
79
68
43
37
35
6
6
6
5
3
3
2
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN1881452
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.92041 ABIN1539740 DB Rabbit Ig pTyr1197 Log in to see Polyclonal
28.92041 ABIN1539739 DB WB Rabbit Ig pTyr1140 Log in to see Polyclonal
28.92041 ABIN3031316 DB ELISA Rabbit Ig Fraction pSer701 Log in to see Polyclonal
1 ABIN1967473 DB ELISA Biotin Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1967243 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1967777 DB ELISA PE Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1967327 DB ELISA APC Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1967577 DB ELISA FITC Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1967681 DB ELISA HRP Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2623783 DB ELISA Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289673 DB ELISA APC Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289677 DB ELISA FITC Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289679 DB ELISA HRP Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289681 DB ELISA PE Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289735 DB ELISA Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN4955081 DB Rabbit Ig Fraction pSer701 Log in to see Polyclonal
1 ABIN2289675 DB ELISA Biotin Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN2289671 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer701 Log in to see Polyclonal
1 ABIN1807040 DB Rabbit pSer701 Log in to see Polyclonal
1 ABIN2794482 DB Rabbit Ig Fraction pSer701 Log in to see Polyclonal

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
Epitope pSer701
(59), (33), (29), (23), (21), (21), (20), (20), (20), (20), (20), (20), (19), (19), (19), (19), (19), (17), (17), (17), (15), (8), (8), (7), (7), (7), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(689), (229), (161), (22), (13), (7), (7), (6), (5), (4), (1), (1)
Host Rabbit
(581), (121), (9), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This IKBKB antibody is un-conjugated
(38), (37), (37), (33), (31), (31), (9), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Dot Blot (DB)
(329), (306), (263), (107), (81), (79), (68), (43), (37), (35), (6), (6), (6), (5), (3), (3), (2), (2), (1)
Pubmed 4 references available
Supplier Log in to see

Product Details anti-IKBKB Antibody

Target Details IKBKB Application Details Handling References for anti-IKBKB antibody (ABIN1881452) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This mouse IKKB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S701 of mouse IKKB.
Clone RB40105

Target Details IKBKB

Product Details anti-IKBKB Antibody Application Details Handling References for anti-IKBKB antibody (ABIN1881452) Images back to top
Antigen
Alternative Name IKKB (IKBKB Antibody Abstract)
Background NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).

Synonyms: Ikbkb, Ikkb, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta
NCBI Accession NP_034676
UniProt O88351
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-IKBKB Antibody Target Details IKBKB Handling References for anti-IKBKB antibody (ABIN1881452) Images back to top
Application Notes DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details References for anti-IKBKB antibody (ABIN1881452) Images back to top
Format Liquid
Concentration 0.45 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-IKBKB antibody (ABIN1881452)

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling Images back to top
Product cited in:

Busuttil, Droin, McCormick, Bernassola, Candi, Melino, Green: "NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 42, pp. 18061-6, 2010

Kenneth, Mudie, Rocha: "IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function." in: The EMBO journal, Vol. 29, Issue 17, pp. 2966-78, 2010

Tsuchiya, Asano, Nakayama, Kato, Karin, Kamata: "Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation." in: Molecular cell, Vol. 39, Issue 4, pp. 570-82, 2010

Farlik, Reutterer, Schindler, Greten, Vogl, Müller, Decker: "Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression." in: Immunity, Vol. 33, Issue 1, pp. 25-34, 2010

Images

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling References for anti-IKBKB antibody (ABIN1881452) back to top
Supplier Images
Dot Blot (DB) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pSer701) antibody (ABIN1881452) Dot blot analysis of mouse IKKB Antibody (Phospho S701) Phospho-specific Pab (ABIN188...