anti-Human IKBKG antibody for Western Blotting

Recommended IKBKG Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Antibodies
  • nemo
  • fj33c07
  • wu:fj33c07
  • zgc:113492
  • MGC97885
  • IKBKG
  • IKBKG_1
  • IKBKG_2
  • CG16910
  • DmIKK-gamma
  • DmIKKgamma
  • Dmel\\CG16910
  • Dmikkgamma
  • IKK
  • IKK-gamma
  • IKK[[gamma]]
  • IKKg
  • IKKgamma
  • KEY
  • Kenny
  • Key
  • dIKK
  • dIKK-gamma
  • dmIKKgamma
  • AMCBX1
  • FIP-3
  • FIP3
  • Fip3p
  • IP
  • IP1
  • IP2
  • IPD2
  • NEMO
  • ZC2HC9
  • Nemo
  • 1110037D23Rik
  • AI848108
  • AI851264
  • AW124339
  • IKK[g]
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • kenny
  • inhibitor of kappaB kinase gamma
  • ikbkg
  • IKBKG
  • LOC782205
  • IKBKG_1
  • key
  • Ikbkg
Epitope
N-Term
37
32
17
14
12
10
9
9
9
7
7
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
331
114
81
9
7
6
5
5
4
3
3
2
2
2
2
1
Host
Rabbit
241
98
3
2
2
Clonality
Polyclonal
Conjugate
This IKBKG antibody is un-conjugated
12
8
8
6
6
6
4
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
264
102
74
60
51
40
25
21
6
5
5
3
2
2
1
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Catalog No. ABIN2779233
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1474795 ABIN2779232 WB Rabbit Middle Region Log in to see Polyclonal 1
3.1474795 ABIN1532742 IF ELISA WB Rabbit IgG AA 51-100 Log in to see Polyclonal 1
3.1474795 ABIN1531713 ELISA WB Rabbit IgG AA 51-100, pSer85 Log in to see Polyclonal 1
3.1474795 ABIN1534228 ELISA WB Rabbit IgG AA 291-340 Log in to see Polyclonal 1
3.1474795 ABIN2706370 IC IF IHC WB Rabbit Center Log in to see Polyclonal
3.1474795 ABIN967646 IP WB Mouse IgG1, kappa Log in to see C73 7
3.1474795 ABIN567775 IHC (p) IP WB Mouse IgG1 AA 262-319 Log in to see EA2-6 2
3.1474795 ABIN968464 IF WB Mouse IgG1 AA 278-396 Log in to see 54-IKKgamma-NEMO 5
3.1474795 ABIN387828 WB Mouse IgG1 full length Log in to see 55AT986-5-78 6
3.1474795 ABIN252492 FACS WB Mouse IgG1 Log in to see 46B844 5
3.1474795 ABIN252501 SimWes WB Mouse IgG1 Log in to see 72C627 7
3.1474795 ABIN567773 WB Mouse IgG1 AA 61-137 Log in to see DA10-12 2
3.1474795 ABIN1532307 IHC ELISA WB Rabbit IgG AA 16-65 Log in to see Polyclonal
3.1474795 ABIN1531287 IHC ELISA WB Rabbit IgG AA 16-65, pSer31 Log in to see Polyclonal
3.1474795 ABIN2668668 WB Mouse IgG1 Log in to see 46B844 1
3.1474795 ABIN967570 WB Mouse IgG1 Log in to see C73 5
3.1474795 ABIN4324313 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 1
3.1474795 ABIN3185153 ELISA IHC WB Rabbit IgG Tyr362 Log in to see Polyclonal
3.1474795 ABIN3185152 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
3.1474795 ABIN3185154 ELISA IF IHC WB Rabbit IgG Tyr363 Log in to see Polyclonal

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Antibodies
Epitope N-Term
(37), (32), (17), (14), (12), (10), (9), (9), (9), (7), (7), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(331), (114), (81), (9), (7), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1)
Host Rabbit
(241), (98), (3), (2), (2)
Clonality
Polyclonal
Conjugate This IKBKG antibody is un-conjugated
(12), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(264), (102), (74), (60), (51), (40), (25), (21), (6), (5), (5), (3), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-IKBKG Antibody

Target Details IKBKG Application Details Handling References for anti-IKBKG antibody (ABIN2779233) Images
Blocking Peptide Blocking peptide for this product available: ABIN978460
Sequence MNRHLWKSQL CEMVQPSGGP AADQDVLGEE SPLGKPAMLH LPSEQGAPET
Predicted Reactivity Cow: 79%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%
Characteristics This is a rabbit polyclonal antibody against IKBKG. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IKBKG

Target Details IKBKG

Product Details anti-IKBKG Antibody Application Details Handling References for anti-IKBKG antibody (ABIN2779233) Images back to top
Antigen
Alternative Name IKBKG (IKBKG Antibody Abstract)
Background IKBKG is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. IKBKG also considered to be a mediator for TAX activation of NF-kappa-B. IKBKG could be implicated in NF-kappa-B-mediated protection from cytokine toxicity.Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males (The International Incontinentia Pigmenti Consortium, 2000 [PubMed 10839543]). In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito (MIM 300337).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2120 AF261086.1 2-2121
Alias Symbols: AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO
Protein Interaction Partner: CHUK, IKBKB, ATM, PIAS4, MALT1, TRIM13, BCL10, SUMO1, UBC, TRAF6, MTOR, RPTOR, RELA, NFKBIA, IKBKG, ARHGDIA, RHOA, CDC37, SRC, FYN, FKBP5, FGR, PPP4C, PPP2R1B, LYN, NMRAL1, USP7, ZC3H12A, IRAK1, USP10, RIPK1, SQSTM1, RNF31, PPP1CC, HDLBP, PPFIA1, PSMB8, K
Protein Size: 419
Molecular Weight 48 kDa
Gene ID 8517
NCBI Accession NM_003639, NP_003630
UniProt Q9Y6K9
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades

Application Details

Product Details anti-IKBKG Antibody Target Details IKBKG Handling References for anti-IKBKG antibody (ABIN2779233) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 419 AA

Restrictions For Research Use only

Handling

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details References for anti-IKBKG antibody (ABIN2779233) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IKBKG antibody (ABIN2779233)

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details Handling Images back to top
Background publications

Salminen, Suuronen, Huuskonen, Kaarniranta: "NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes?" in: Biochemical and biophysical research communications, Vol. 367, Issue 4, pp. 715-8, 2008

Images

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details Handling References for anti-IKBKG antibody (ABIN2779233) back to top
Supplier Images
Western Blotting (WB) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) (N-Term) antibody (ABIN2779233) WB Suggested Anti-IKBKG Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive...