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anti-Monkey IL1RN antibody for Functional Studies

Recommended IL1RN Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
  • DIRA
  • F630041P17Rik
  • ICIL-1RA
  • icIL-1ra
  • IL-1RA
  • IL-1ra
  • IL-1ra3
  • IL-1RN
  • IL1F3
  • IL1RA
  • IL1RN
  • IRAP
  • IRAP1
  • MVCD4
Reactivity
Human, Monkey
174
29
19
12
9
7
5
4
4
4
2
Host
Rabbit
138
74
7
3
2
2
1
Clonality
Polyclonal
Conjugate
This IL1RN antibody is un-conjugated
33
25
7
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
133
115
41
22
20
18
18
17
11
9
9
8
3
3
2
2
2
1
1
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Catalog No. ABIN116864
$ 1,435.50
Plus shipping costs $45.00

Top referenced anti-IL1RN antibody for Functional Studies

Similar anti-IL1RN Antibodies

Application / Reactivity Monkey Human
ELISA 3 Antibodies 81 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 10 Antibodies
Functional Studies (Func) 1 Antibodies 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies
Western Blotting (WB) 1 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Dot Blot (DB) 2 Antibodies
Flow Cytometry (FACS) 19 Antibodies
Immunoassay (IA) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 32 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies

General

Antigen Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
Reactivity Human, Monkey
(174), (29), (19), (12), (9), (7), (5), (4), (4), (4), (2)
Host Rabbit
(138), (74), (7), (3), (2), (2), (1)
Clonality
Polyclonal
Conjugate This IL1RN antibody is un-conjugated
(33), (25), (7), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(133), (115), (41), (22), (20), (18), (18), (17), (11), (9), (9), (8), (3), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-IL1RN Antibody

Target Details IL1RN Application Details Handling References for anti-IL1RN Antibody (ABIN116864) Images
Purification DEAE Chromatography.
Immunogen Prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.

Target Details IL1RN

Product Details anti-IL1RN Antibody Application Details Handling References for anti-IL1RN Antibody (ABIN116864) Images back to top
Antigen
Alternative Name IL1RN / IL1RA (IL1RN Antibody Abstract)
Background IL1RA is a member of the Interleukin 1 cytokine family. This protein inhibits the activities of Interleukin 1, alpha (IL1A) and Interleukin 1, beta (IL1B), and modulates a variety of Interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: ICIL-1RA, IL-1RN, IL-1ra, IL1 inhibitor, IL1F3, IRAP, Interleukin-1 receptor antagonist protein
Gene ID 9606
UniProt P18510
Pathways NF-kappaB Signaling

Application Details

Product Details anti-IL1RN Antibody Target Details IL1RN Handling References for anti-IL1RN Antibody (ABIN116864) Images back to top
Application Notes This IgG fraction antibody of anti-Human IL-1 Receptor Antagonist has been tested for usein Neutralizations, ELISA, Radioimmunoassays, Western blotting, Immunohistochemistryand Flow cytometry. Reactivity in other immunoassays is unknown. Note: This product has been assayed by immunoblot using HRP Goat-anti-Rabbit IgG [H&L]and TMB as a substrate. A working dilution range of 1: 400 to 1: 800 is suggested for thisapplication. This product has been assayed by ELISA against IL-1Receptor Antagonist usingHRP Conjugated Anti-Rabbit IgG [H&L] (Goat) and ABTS as a substrate for 30 minutes atroom temperature. A working dilution range of 1: 500 to 1: 1,000 is suggested for thisproduct. For use in ELISA formats, this antibody is best used as the second antibody incombination with a monoclonal antibody as a capture antibody. This product has beenassayed by Immunohistochemistry. A dilution of 1: 400 or greater is suggested for thisimmunoassay. Either paraffin fixation or cryofixation can be used forImmunohistochemistry. This product has been assayed by radioimmunoassay againstantigen. A dilution of 1: 8,000 is suggested for this immunoassay. Recommended Dilutions: ELISA: 1/1,000-1/5,000. Western Blot: 1/500-1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details References for anti-IL1RN Antibody (ABIN116864) Images back to top
Concentration 1.0 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized product at 2-8 °C. After reconstitution, store at -20 °C.

References for anti-IL1RN Antibody (ABIN116864)

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Handling Images back to top
Background publications

Arend, Malyak, Guthridge, Gabay: "Interleukin-1 receptor antagonist: role in biology." in: Annual review of immunology, Vol. 16, pp. 27-55, 1998

Hammerberg, Arend, Fisher, Chan, Berger, Haskill, Voorhees, Cooper: "Interleukin-1 receptor antagonist in normal and psoriatic epidermis." in: The Journal of clinical investigation, Vol. 90, Issue 2, pp. 571-83, 1992

Haskill, Martin, Van Le, Morris, Peace, Bigler, Jaffe, Hammerberg, Sporn, Fong: "cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 9, pp. 3681-5, 1991

Eisenberg, Evans, Arend, Verderber, Brewer, Hannum, Thompson: "Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist." in: Nature, Vol. 343, Issue 6256, pp. 341-6, 1990