Browse our MAP3K7 (MAP3K7) ELISA Kits

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Mitogen-Activated Protein Kinase Kinase Kinase 7 ELISA Kits (MAP3K7)
On www.antibodies-online.com are 10 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) ELISA Kits from 4 different suppliers available. Additionally we are shipping MAP3K7 Antibodies (177) and MAP3K7 Proteins (7) and many more products for this protein. A total of 214 MAP3K7 products are currently listed.
Synonyms:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612
list all ELISA KIts Gene Name GeneID UniProt
MAP3K7 313121 P0C8E4
MAP3K7 6885 O43318
MAP3K7 26409 Q62073

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MAP3K7 (MAP3K7) ELISA Kits by Reactivity

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More ELISA Kits for MAP3K7 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. TAK1 regulates Nrf2 (show GABPA ELISA Kits) through modulation of Keap-p62/SQSTM1 (show SQSTM1 ELISA Kits) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  2. Overexpression of TAK1 was strongly associated with positive lymph node metastasis in pancreatic ductal adenocarcinoma.

  3. dysregulation of the TAK1 complex produces a close phenocopy of Frontometaphyseal Dysplasia caused by FLNA (show FLNA ELISA Kits) mutations; furthermore, the pathogenesis of some of the filaminopathies caused by FLNA (show FLNA ELISA Kits) mutations might be mediated by misregulation of signaling coordinated through the TAK1 signaling complex

  4. although TAK1 is located at the crossroad of inflammation, immunity, and cancer, this study reports MAP3K7 mutations in a developmental disorder affecting mainly cartilage, bone, and heart

  5. This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

  6. TAK1 may be an important factor involved in the pathogenesis of thyroid cancer, and targeted down-regulation of TAK1 may improve the prognosis of patients with thyroid cancer.

  7. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  8. This paper highlights that targeting the BMP and TGFbeta (show TGFB1 ELISA Kits) type I and type II receptors causes a downregulation of XIAP (show XIAP ELISA Kits), TAK1, and Id1 (show ID1 ELISA Kits) leading to cell death of lung cancer cells.

  9. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (show TLR4 ELISA Kits)-mediated JNK (show MAPK8 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) Activation

  10. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. Transforming growth factor-beta activated kinase 1 (TAK1) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) development.

  2. TAK1 (show NR2C2 ELISA Kits) regulates Nrf2 (show NFE2L2 ELISA Kits) through modulation of Keap-p62/SQSTM1 (show SQSTM1 ELISA Kits) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  3. Mekk1 (show MAP2K1 ELISA Kits) (encoded by Map3k1 (show MAP3K1 ELISA Kits)) signaling activates Mapks to regulate Cdkn1b (show CDKN1B ELISA Kits) (encoding p27(Kip1 (show CDKN1B ELISA Kits))) expression and p27(Kip1 (show CDKN1B ELISA Kits))-dependent proliferative expansion in response to antigen.

  4. TRADD (show TRADD ELISA Kits) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (show NR2C2 ELISA Kits)/p38 MAPK (show MAPK14 ELISA Kits) but not AKT (show AKT1 ELISA Kits) phosphorylation

  5. this study demonstrates a pivotal role of TAK1 (show NR2C2 ELISA Kits) in dendritic cells in controlling trichloroethylene-induced contact hypersensitivity response and suggests that targeting TAK1 (show NR2C2 ELISA Kits) function in DCs may be a viable approach to preventing and treating TCE-related occupational health hazards

  6. The E3 ligase TRIM8 (show TRIM8 ELISA Kits) is a potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1.

  7. Angiotensin-II up-regulates the Ampkalpha1 (show PRKAA1 ELISA Kits) isoform in renal tissue. Ampkalpha1 (show PRKAA1 ELISA Kits) participates in renal Tak1 (show NR2C2 ELISA Kits) activation and Tak1 (show NR2C2 ELISA Kits)-dependent signaling induced by angiotensin-II.

  8. TRIM8 (show TRIM8 ELISA Kits) could promote K63-linked polyubiquitination of transforming growth factor beta-activated kinase 1 (TAK1), leading to the activation of TAK1 (show NR2C2 ELISA Kits) and enhanced inflammatory responses.

  9. TAK1 (show NR2C2 ELISA Kits) signaling preserved the viability of lambda-chain-positive B cells by maintaining Bcl-2 (show BCL2 ELISA Kits) expression through IKK (show CHUK ELISA Kits)-NF-kappaB (show NFKB1 ELISA Kits) signaling

  10. Data show that TGFbeta (show TGFB1 ELISA Kits)-activated kinase-1 (TAK1 (show NR2C2 ELISA Kits)) activated nuclear factor of activated T-cells (NFAT (show NFATC1 ELISA Kits))/NF-kappa B (NFkappaB (show NFKB1 ELISA Kits)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (show BNIP3 ELISA Kits)), and inhibited cardiac cell death.

MAP3K7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) Elisa Kit
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) Elisa Kit
  • B430101B05 Elisa Kit
  • C87327 Elisa Kit
  • MEKK7 Elisa Kit
  • si:ch211-225h9.1 Elisa Kit
  • TAK1 Elisa Kit
  • TGF1a Elisa Kit
  • zgc:110612 Elisa Kit

Protein level used designations for MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPECIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
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