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Browse our anti-NFKBIA (NFKBIA) Antibodies

Full name:
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha Antibodies (NFKBIA)
On www.antibodies-online.com are 383 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies from 36 different suppliers available. Additionally we are shipping NFKBIA Kits (28) and NFKBIA Proteins (10) and many more products for this protein. A total of 441 NFKBIA products are currently listed.
Synonyms:
AI462015, ECI-6/IKBA, IKBA, MAD-3, NFKBI, RL/IF-1
list all antibodies Gene Name GeneID UniProt
NFKBIA 18035 Q9Z1E3
NFKBIA 4792 P25963
NFKBIA 25493 Q63746

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All available anti-NFKBIA Antibodies

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Top referenced anti-NFKBIA Antibodies

  1. Human Polyclonal NFKBIA Primary Antibody for EIA, WB - ABIN357736 : Miskolci, Castro-Alcaraz, Nguyen, Vancura, Davidson, Vancurova: Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils. in Archives of biochemistry and biophysics 2003 (PubMed)
    Show all 5 references for ABIN357736

  2. Human Polyclonal NFKBIA Primary Antibody for DB - ABIN650851 : Wu, Walenkamp, Lankester, Bidlingmaier, Wit, De Luca: Growth hormone and insulin-like growth factor I insensitivity of fibroblasts isolated from a patient with an I{kappa}B{alpha} mutation. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)
    Show all 2 references for ABIN650851

  3. Human Polyclonal NFKBIA Primary Antibody for FACS, IF - ABIN652417 : Tojima, Fujimoto, Delhase, Chen, Hatakeyama, Nakayama, Kaneko, Nimura, Motoyama, Ikeda, Karin, Nakanishi: NAK is an IkappaB kinase-activating kinase. in Nature 2000 (PubMed)
    Show all 2 references for ABIN652417

  4. Human Polyclonal NFKBIA Primary Antibody for WB - ABIN389074 : Place, Haspeslagh, Giardina: Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation. in Journal of cellular physiology 2003 (PubMed)

  5. Human Monoclonal NFKBIA Primary Antibody for IP, IHC - ABIN223053 : Ren, Gao, Wu: TLR4: the receptor bridging Acanthamoeba challenge and intracellular inflammatory responses in human corneal cell lines. in Immunology and cell biology 2010 (PubMed)

  6. Chicken Polyclonal NFKBIA Primary Antibody for WB - ABIN2792116 : Truhlar, Mathes, Cervantes, Ghosh, Komives: Pre-folding IkappaBalpha alters control of NF-kappaB signaling. in Journal of molecular biology 2008 (PubMed)

  7. Human Polyclonal NFKBIA Primary Antibody for IHC, WB - ABIN2792665 : Janssen, van Wengen, Hoeve, ten Dam, van der Burg, van Dongen, van de Vosse, van Tol, Bredius, Ottenhoff, Weemaes, van Dissel, Lankester: The same IkappaBalpha mutation in two related individuals leads to completely different clinical syndromes. in The Journal of experimental medicine 2004 (PubMed)

  8. Human Polyclonal NFKBIA Primary Antibody for IF, IHC - ABIN1531880 : Haskill, Beg, Tompkins, Morris, Yurochko, Sampson-Johannes, Mondal, Ralph, Baldwin: Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. in Cell 1991 (PubMed)

More Antibodies against NFKBIA Interaction Partners

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) interaction partners

  1. SM22alpha (show TAGLN Antibodies) is a phosphorylation-regulated (show PHAX Antibodies) suppressor of IKK (show CHUK Antibodies)-IkappaBalpha-NF-kappaB (show NFKB1 Antibodies) signaling cascades.

  2. We found potential links between the alterations in expression of Tsc22d3 (show TSC22D3 Antibodies), Nfkbia and Pdyn (show PDYN Antibodies), and different aspects of susceptibility to stress.

  3. Specific and constitutive deletion of the inhibitor of NF-kappaB (show NFKB1 Antibodies) (IkappaBalpha) in eosinophils in vivo reduced apoptosis during helminth infection

  4. GRK6 (show GRK6 Antibodies) directly phosphorylates Nfkbia at Ser32/Ser36. Knockdown of GRK6 (show GRK6 Antibodies) suppresses TNF-alpha (show TNF Antibodies)-induced NF-kappaappaB signaling.

  5. Results demonstrate novel roles of TNFRII (show TNFRSF1B Antibodies) in the regulation of Abeta (show APP Antibodies) production, suggesting a potential therapeutic strategy for Alzheimer's disease by up-regulating TNFRII (show TNFRSF1B Antibodies) levels and elevating phosphorylated IkappaBalpha by SUMOylation.

  6. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IkappaBalpha.

  7. Dengue virus protease interacts with both NF-kappaB inhibitor alpha (IkappaBalpha) and NF-kappaB (show NFKB1 Antibodies) inhibitor beta (IkappaBbeta (show NFKBIB Antibodies)), cleaving them in a mouse hemorrhage model.

  8. The results indicate that following heat shock treatment, HuR (show ELAVL1 Antibodies) translocates from the nucleus to the cytoplasm, forming stress granules and regulating the translation of IkBalpha mRNA without affecting the half-life.

  9. Data show that inhibition of nuclear factor-kappaB (NF-kappaB (show NFKB1 Antibodies)) in IKBM protects the mice from monocrotaline (MCT (show MCAT Antibodies))-induced pulmonary arterial hypertension and right ventricular hypertrophy.

  10. Wedelolactone inhibited lipopolysaccharide -induced NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) activation via the degradation and phosphorylation of IkappaB-alpha and subsequent translocation of the NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) subunit to the nucleus.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) interaction partners

  1. the rs3138053 polymorphism of NFKBIA gene is a candidate for susceptibility to overall cancers, while rs696 plays a protective role [meta-analysis]

  2. Identify a novel BCR-ABL (show ABL1 Antibodies)/IkappaBalpha/p53 (show TP53 Antibodies) network, whereby BCR-ABL (show ABL1 Antibodies) functionally inactivates a key tumor suppressor in chronic myeloid leukemia (show BCL11A Antibodies).

  3. Study demonstrates an association between functional polymorphisms of IkappaBalpha rs696 and smoking with the risk of defective spermatogenesis, suggesting some interaction between the NF-kappaB (show NFKB1 Antibodies) signalling pathway and smoking-related ROS (show ROS1 Antibodies) in human spermatogenesis.

  4. MicroRNA-19a mediates gastric carcinoma cell proliferation through the activation of IkappaBalpha.

  5. No association was observed between NFKBIA variants and risk of liver cancer.

  6. Data indicate the involvement of the p38 MAPK (show MAPK14 Antibodies)/NF-kappaB (show NFKB1 Antibodies)/IkappaBalpha pathway in Newcastle disease virus (NDV) infection and subsequent induction of apoptosis in clear cell renal cell carcinoma (show MOK Antibodies) (ccRCC) cells.

  7. SM22alpha (show TAGLN Antibodies) is a phosphorylation-regulated (show PHAX Antibodies) suppressor of IKK (show CHUK Antibodies)-IkappaBalpha-NF-kappaB (show NFKB1 Antibodies) signaling cascades.

  8. This study aimed to examine the association between NFKB19-4 ATTG ins (show INS Antibodies)-->del, NFKBIA 3' UTR (show UTS2R Antibodies) A-->G, -826CT and -881AG polymorphisms and prostate cancer risk among Chinese.

  9. Our study indicates that NFKB1 (show NFKB1 Antibodies)-94 ins (show INS Antibodies)/del ATTG polymorphism may play a role in CAD (show CAD Antibodies) susceptibility in Chinese Uygur population

  10. genetic variants in NFkappaB1 (rs28362491del>ins (show INS Antibodies) ATTG) and IkappaBalpha (rs696G>A) and their synergistic effect might contribute to nasopharyngeal carcinoma predisposition.

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) interaction partners

  1. IkappaB-alpha protein was stabilized by COMMD1 (show COMMD1 Antibodies), which attenuated NF-kappaB (show NFKB1 Antibodies) signaling during Toll (show TLR4 Antibodies)-like receptor ligand and tumor necrosis factor alpha (show TNF Antibodies) treatment and enhanced HIV-1 latency in latently HIV-1-infected cells.

  2. NFKBIA has a role as a marker of NF-kappaB (show NFKB1 Antibodies)/p65 (show SYT1 Antibodies) activation in the early embryo.

  3. NF-kappaB (show NFKB1 Antibodies) has a role in increasing PDGF-B (show PDGFB Antibodies) transcription

  4. AIP1 (show PDCD6IP Antibodies) is a novel transducer in TNF (show TNF Antibodies)-induced TRAF2 (show TRAF2 Antibodies)-dependent activation of ASK1 (show MAP3K5 Antibodies) that mediates a balance between JNK (show MAPK8 Antibodies) versus NF-kappaB (show NFKB1 Antibodies) signaling

  5. GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.

NFKBIA Antigen Profile

Antigen Summary

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Alternative names and synonyms associated with NFKBIA

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (LOC100220015) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (LOC100357341) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha (Nfkbia) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia) antibody
  • AI462015 antibody
  • ECI-6/IKBA antibody
  • IKBA antibody
  • MAD-3 antibody
  • NFKBI antibody
  • RL/IF-1 antibody

Protein level used designations for NFKBIA

NF-kappa-B inhibitor alpha , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha , I(Kappa)B(alpha) , I-kappa-B-alpha , I-kappaBalpha , ikB-alpha , ikappaBalpha , nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha , nuclear factor of kappa light polyp gene enhancer in B-cell 1 , IkappaBalpha , major histocompatibility complex enhancer-binding protein MAD3 , nuclear factor of kappa light chain gene enhancer in B-cells , ECI-6 , I kappa B-alpha , IKB-alpha , NF-kappaB inhibitor alpha , REL-associated protein pp40 , Rel-associated pp40 , IkappaB alpha , Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha , Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha

GENE ID SPECIES
780520 Ovis aries
100220015 Taeniopygia guttata
100357341 Oryctolagus cuniculus
18035 Mus musculus
4792 Homo sapiens
406188 Sus scrofa
396093 Gallus gallus
480291 Canis lupus familiaris
282291 Bos taurus
25493 Rattus norvegicus
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