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Rat (Rattus) NFKBIB ELISA Kit - ABIN585318
Wang, Ge, Yang, Zhai, Yang, Wang, Liu, Shi, Wu: Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis. in International immunopharmacology 2011
IkappaBbeta has essential functions within the Rel-NFkappaB generation module, specifically for the RelA:RelA homodimer, which controls a subset of NFkappaB target genes.
these results mechanistically link the innate immune response mediated by IkappaBbeta/NF-kappaB (show NFKB1 ELISA Kits) to ET-1 (show EDN1 ELISA Kits) expression and potentially reveal therapeutic targets for patients with Gram-negative septic shock.
Dengue virus protease interacts with both IkappaBalpha (show NFKBIA ELISA Kits) and IkappaBbeta cleaving them in a mouse hemorrhage model.
sustained NF-kappaB (show NFKB1 ELISA Kits) activity mediated by IkappaBbeta protects against hyperoxic lung injury through increased expression of antiapoptotic genes
Findings represent a necessary but not sufficient role of IkappaBbeta in preventing oxidant stress-induced cell death.
IkappaBbeta is an essential co-activator for LPS (show TLR4 ELISA Kits)-induced IL-1beta (show IL1B ELISA Kits) transcription in vivo.
IkappaBbeta acts through p65 (show NFkBP65 ELISA Kits):c-Rel (show NFkBP65 ELISA Kits) dimers to maintain prolonged expression of TNF-alpha (show TNF ELISA Kits)
data suggest that RelA (show NFkBP65 ELISA Kits) is liberated during LPS (show TLR4 ELISA Kits)-induced pulmonary inflammation by the regulated degradation of both IkappaB-alpha (show NFKBIA ELISA Kits) and IkappaB-beta
temporal control of NF-kappaB (show NFKB1 ELISA Kits) activation by the coordinated degradation and synthesis of IkappaB proteins
beta-TrCP1 (show BTRC ELISA Kits) contributes to, but is not absolutely required for, the degradation of I kappa B and beta-catenin (show CTNNB1 ELISA Kits)
our data establish the importance of a novel tumor suppressive IKBB gene in abrogating angiogenesis in NPC (show NPC1 ELISA Kits) via the NF-kappaB (show NFKB1 ELISA Kits) signalling pathway.
IkappaBbeta may be a novel target for transcription factors of the HMG (show SSRP1 ELISA Kits)-box SRY (show SRY ELISA Kits)/Sox (show PIPOX ELISA Kits) family and imply a potential role for NF-kappaB (show NFKB1 ELISA Kits)/IkappaBbeta in spermatogenesis
Data show that increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa (show NFKBIA ELISA Kits), IkBb-1 and IkBb-2.
VEGF (show VEGFA ELISA Kits) increased Mn-superoxide dismutase (show SOD2 ELISA Kits) promoter activity, an effect that was dependent on a second intronic NF-kappaB (show NFKB1 ELISA Kits) consensus motif.
data indicate that inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta (show IKBKB ELISA Kits)
None of the NFKBIB SNPs are associated with pneumococcal susceptibility.
NF-kappaB (show NFKB1 ELISA Kits), IkappaB-alpha (show NFKBIA ELISA Kits), IkappaB-beta mRNA decreased significantly after weight loss.
increased I-kappaBbeta expression reversed NF-kappaB (show NFKB1 ELISA Kits) activation in cancer cells, compensating for the loss of I-kappaBalpha (show NFKBIA ELISA Kits) via TGase 2 (show TGM2 ELISA Kits) polymerization.
NFKBIA (show NFKBIA ELISA Kits) and NFKBIB are not likely to harbor ovarian cancer risk alleles.
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
, NF-kappa-B inhibitor beta
, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta
, TR-interacting protein 9
, thyroid receptor-interacting protein 9