You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our NFKBIE Proteins (NFKBIE)

Full name:
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon Proteins (NFKBIE)
On www.antibodies-online.com are 4 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) Proteins from 3 different suppliers available. Additionally we are shipping NFKBIE Antibodies (100) and NFKBIE Kits (9) and many more products for this protein. A total of 117 NFKBIE products are currently listed.
Synonyms:
IKBE, NFKBIE, Slc35b2
list all proteins Gene Name GeneID UniProt
NFKBIE 18037 O54910
NFKBIE 4794 O00221
Rat NFKBIE NFKBIE 316241  

Show all synonyms

NFKBIE Proteins (NFKBIE) by Origin

Select your origin of interest

More Proteins for NFKBIE Interaction Partners

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) interaction partners

  1. The data imply that regulation of these c-Rel (show NFkBP65 Proteins)-dependent lymphoid responses is a non-redundant function of IkappaBepsilon.

  2. temporal control of NF-kappaB (show NFKB1 Proteins) activation by the coordinated degradation and synthesis of IkappaB proteins

  3. IkappaBepsilon deficiency in mice leads to neonatal death, elevated kappaB binding activity, overexpression of NF-kappaB (show NFKB1 Proteins) target genes, and disruption of lymphocyte production.

  4. Neither IkappaBalpha (show NFKBIA Proteins) nor IkappaBepsilon deficiency had major effects on natural killer cell generation while their combined absence led to NF-kappaB (show NFKB1 Proteins) hyperactivation.

  5. An important role is proposed for I kappa B epsilon in the differential regulation of nuclear NF-kappa B (show NFKB1 Proteins) activity in stimulated B cells.

  6. In vivo degradation rate constants were measured for NF-kappaB (show NFKB1 Proteins)-bound & -unbound IkappaB. Models suggest differential degradation rates of free & bound IkappaB may be a new cross-regulation mechanism imparting functional robustness to the signaling module.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) interaction partners

  1. results show that Gal-1 (show LGALS1 Proteins) acts by inhibiting the stimulation of the LPS (show IRF6 Proteins)-induced IkappaBzeta (show NFKBIZ Proteins) expression, an NF-kappaB (show NFKB1 Proteins) regulator involved in IL-6 (show IL6 Proteins) gene transcription.

  2. Newly identified alterations included recurrent promoter mutations of NFKBIE, encoding NF-kappaB (show NFKB1 Proteins) inhibitor varepsilon (IkappaBvarepsilon), in 14.5% of samples of desmoplastic melanoma

  3. IkappaBepsilon has a role in NF-kappaB (show NFKB1 Proteins) regulation in aggressive chronic lymphocytic leukemia

  4. Vitamin C forestalls cigarette smoke induced NF-kappaB (show NFKB1 Proteins) activation in alveolar epithelial cells.

  5. we identified two gene loci associated with rheumatoid arthritis susceptibility- NFKBIE and RTKN2 (show RTKN2 Proteins)

  6. Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon

  7. An NFKBIE SNP associated with susceptibility to pneumococcal disease but not pneumococcal empyema.

  8. Expression levels of GGT1 (show GGT1 Proteins) and possibly NFKBIE might be useful as biomarkers of genetic susceptibility to arsenite.

  9. Genomic mutation of the NFKBIE gene in primary Hodgkin/ Reed Sternberg cells

NFKBIE Protein Profile

Protein Summary

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Alternative names and synonyms associated with NFKBIE

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE)
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon (Nfkbie)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (Nfkbie)
  • IKBE protein
  • NFKBIE protein
  • Slc35b2 protein

Protein level used designations for NFKBIE

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon , I-kappa-B-epsilon , NF-kappa-B inhibitor epsilon , NF-kappa-BIE , ikB-E , ikB-epsilon , ikappaBepsilon , solute carrier family 35, member B2

GENE ID SPECIES
462730 Pan troglodytes
609647 Canis lupus familiaris
100591878 Nomascus leucogenys
18037 Mus musculus
4794 Homo sapiens
506727 Bos taurus
316241 Rattus norvegicus
Selected quality suppliers for NFKBIE Proteins (NFKBIE)
Did you look for something else?