NFKBIE Protein (His tag)
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- Target See all NFKBIE Proteins
- NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NFKBIE protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NFKBIE / IKBE (N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFKBIE Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
- Alternative Name
- Nfkbie,ikbe (NFKBIE Products)
- Synonyms
- NFKBIE Protein, IKBE Protein, Slc35b2 Protein, NFKB inhibitor epsilon Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon Protein, NFKBIE Protein, Nfkbie Protein
- Background
- The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.
- Molecular Weight
- 29.3 kDa
- NCBI Accession
- NP_004547
- Pathways
- NF-kappaB Signaling, Maintenance of Protein Location
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