Browse our TNFRSF13C Proteins (TNFRSF13C)

Full name:
Tumor Necrosis Factor Receptor Superfamily, Member 13C Proteins (TNFRSF13C)
On are 36 Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Proteins from 12 different suppliers available. Additionally we are shipping TNFRSF13C Antibodies (218) and TNFRSF13C Kits (44) and many more products for this protein. A total of 315 TNFRSF13C products are currently listed.
2010006P15Rik, BAFF-R, Baffr, Bcmd, Bcmd-1, Bcmd1, BROMIX, CD268, CVID4, Lvis22, prolixin, RGD1560810, TNFRSF13C
list all proteins Gene Name GeneID UniProt
TNFRSF13C 500910  
TNFRSF13C 115650 Q96RJ3
TNFRSF13C 72049 Q9D8D0

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TNFRSF13C Proteins (TNFRSF13C) by Origin

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Top referenced TNFRSF13C Proteins

  1. Rat (Rattus) TNFRSF13C Protein expressed in Human Cells - ABIN2009241 : Laâbi, Egle, Strasser: TNF cytokine family: more BAFF-ling complexities. in Current biology : CB 2001 (PubMed)
    Show all 2 references for 2009241

  2. Rat (Rattus) TNFRSF13C Protein expressed in Human Cells - ABIN2009243 : Defrance, Casamayor-Pallejà, Krammer: The life and death of a B cell. in Advances in cancer research 2002 (PubMed)
    Show all 2 references for 2009243

More Proteins for TNFRSF13C Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) interaction partners

  1. The expression levels of serum BAFF (show TNFSF13B Proteins) and the three receptors (TACI (show TNFRSF13B Proteins), BCMA (show TNFRSF17 Proteins) and BAFF-R) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.

  2. Variants in BAFF-R gene is associated with chronic lymphocytic leukemia.

  3. BAFF-R, as the principal receptor of BAFF (show TNFSF13B Proteins), not only decreased the apoptosis of B cells and CD8 (show CD8A Proteins)+ T cells by upregulating the expression of Bcl-2 (show BCL2 Proteins) and BclxL (show BCL2L1 Proteins), but also promoted B-cell proliferation in immune thrombocytopenia.

  4. BAFF (show TNFSF13B Proteins) and BAFF-R are expressed in the thyrocytes derived from patients with either autoimmune thyroid disorders or multinodular goiter, as well in the infiltrating immune cells of Graves' disease and Hashimoto's thyroiditis

  5. There is an increased prevalence of the BAFF-R His159Tyr mutation in patients with Sjogren's syndrome (SS), particularly in those with SS complicated by MALT lymphoma whose disease onset occurred at a younger age.

  6. Expression of mutant caspase-9 (show CASP9 Proteins) correlated with a downregulation of BAFFR (B-cell-activating factor (show TNFSF13B Proteins) belonging to the TNF (show TNF Proteins) family (BAFF) receptor) in B cells and ICOS (inducible T-cell costimulator (show ICOS Proteins)) in T cells.

  7. Variants of TNFRSF13C were associated with common variable immunodeficiency.

  8. Negative expression of BAFF-R, but not of BAFF (show TNFSF13B Proteins), could be an independent risk factor for progression-free survival and Overall survival in patients with diffuse large B-cell lymphoma treated with standard R-CHOP (show DDIT3 Proteins).

  9. the common TLR4 (show TLR4 Proteins)-D299G, TLR4 (show TLR4 Proteins)-T399I and BAFFR-P21R polymorphisms provide the carriers with a protective advantage against ICU-acquired sepsis; this finding was more profound for medical patients compared to trauma or surgical ones

  10. Data show significant differences in expression of tumour necrosis factor (show TNF Proteins) family (BAFF (show TNFSF13B Proteins)) receptors BAFF-R, BCMA (show TNFRSF17 Proteins) and TACI (show TNFRSF13B Proteins) in patients with and without anti-Jo-1 or anti-Ro52 (show TRIM21 Proteins)/anti-Ro60 (show TROVE2 Proteins) autoantibodies.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) interaction partners

  1. B cell-activating factor (BAFF (show TNFSF13B Proteins)) upregulates CD28 (show CD28 Proteins)/B7 and CD40 (show CD40 Proteins)/CD154 (show CD40LG Proteins) expression, and promotes the interactions between T and B cells in a BAFF receptor-dependent manner.

  2. conclude that P44S BAFFR mutation does not hinder BAFFR function or enhance B cell activity in MRL/Lpr (show FAS Proteins) and MRL mice and that other susceptibility loci on the MRL background contributed to the hyperactivity of these cells

  3. Results from this study suggest blockade of CXCL13 (show CXCL13 Proteins) and BAFFR together may be an effective therapeutic strategy in preventing salivary hypofunction and reducing autoantibody titers and sialadenitis in patients with Sjogren's syndrome

  4. Heteromers consisting of one BAFF (show TNFSF13B Proteins) and two APRIL bind to receptor TACI (show TNFRSF13B Proteins), BCMA (show TNFRSF17 Proteins) but not to BAFFR.

  5. Syk (show SYK Proteins)-deficient B cells require BAFF receptor and CD19 (show CD19 Proteins)/PI3K signaling for their long-term survival.

  6. In conclusion, BAFFR signaling affects both innate and adaptive immune activation during viral infections.

  7. BAFF (show TNFSF13B Proteins) controls neural cell survival through BAFF receptor.

  8. BAFF receptor deficiency limits Murid herpesvirus 4 infection.

  9. Although we have found that TACI is dispensable for controlling B. hermsii infection, mice deficient in BAFFR or BAFF exhibit impairment in B. hermsii-specific IgM responses and clearance of bacteremia.

  10. tnfrsf13c is dispensable for the development of SLE in NZM mice.

TNFRSF13C Protein Profile

Protein Summary

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Alternative names and synonyms associated with TNFRSF13C

  • tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C)
  • tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c)
  • tumor necrosis factor receptor superfamily member 13C-like (LOC618516)
  • 2010006P15Rik protein
  • BAFF-R protein
  • Baffr protein
  • Bcmd protein
  • Bcmd-1 protein
  • Bcmd1 protein
  • BROMIX protein
  • CD268 protein
  • CVID4 protein
  • Lvis22 protein
  • prolixin protein
  • RGD1560810 protein
  • TNFRSF13C protein

Protein level used designations for TNFRSF13C

tumor necrosis factor receptor superfamily, member 13C , tumor necrosis factor receptor superfamily member 13C , B cell-activating factor receptor , B-cell-activating factor receptor , BAFF receptor , BLyS receptor 3 , B-cell maturation defect 1 , b cell-activating factor receptor

417983 Gallus gallus
500910 Rattus norvegicus
607785 Canis lupus familiaris
618516 Bos taurus
746611 Pan troglodytes
115650 Homo sapiens
72049 Mus musculus
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