Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Presenilin 1 Proteins

(Presenilin 1 (PSEN1))
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1\; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq, Aug 2008].

8 results :

PSEN1 Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA
Catalog No. ABIN1316518
 
PSEN1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Catalog No. ABIN7414045
 
PSEN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Catalog No. ABIN7412977
 
PSEN1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Catalog No. ABIN7396037
 
PSEN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729570
 
PSEN1 Origin: Human, Cat, Cow, Monkey, Pig Host: Escherichia coli (E. coli) Recombinant WB, PC
Catalog No. ABIN2751149
 
PSEN1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6382191
 
PSEN1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6382195
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Positive Control (PC)
    • Immunogen (Imm)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cat
    • Cow
    • Monkey
    • Pig
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 280-379
    • Transcript Variant 1
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Abbexa
    • FabGennix
    • OriGene

Aliases for Presenilin 1 Proteins

presenilin 1 (psen1) Proteins
presenilin 1 (PSEN1) Proteins
presenilin 1 (Psen1) Proteins
presenilin 1 L homeolog (psen1.L) Proteins
ad3 Proteins
AD3 Proteins
Ad3h Proteins
fad Proteins
FAD Proteins
pre1 Proteins
PS-1 Proteins
ps1 Proteins
PS1 Proteins
psen Proteins
s182 Proteins
S182 Proteins
X-PS-alpha Proteins
X-PS-beta Proteins
zf-PS1 Proteins
zfPS1 Proteins
You are here:
Chat with us!