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Browse our MED1 Proteins (MED1)

Full name:
Mediator Complex Subunit 1 Proteins (MED1)
On www.antibodies-online.com are 4 Mediator Complex Subunit 1 (MED1) Proteins from 3 different suppliers available. Additionally we are shipping MED1 Antibodies (70) and MED1 Kits (20) and many more products for this protein. A total of 103 MED1 products are currently listed.
Synonyms:
AI480703, CG7162, CRSP1, CRSP200, CRSP210, Dmel\\CG7162, DRIP205, DRIP230, dTRAP220, l11Jus15, Med1, Med1/SOP3/TRAP220, nbr1, PBP, Pparbp, PPARGBP, RB18A, RGD1559552, TRAP220, TRIP2
list all proteins Gene Name GeneID UniProt
MED1 5469 Q15648
MED1 19014 Q925J9
Rat MED1 MED1 497991  

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MED1 Proteins (MED1) by Origin

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Human Mediator Complex Subunit 1 (MED1) interaction partners

  1. Our data indicate that MED1 serves as a key mediator in ARv567es induced gene expression

  2. Results show that miR-1 (show FSD1 Proteins) is downregulated in osteosarcoma cells but both of its targets Med1 and Med31 (show MED31 Proteins) were overexpressed suggesting that MiR-1 (show FSD1 Proteins) plays an important role on the proliferation of osteosarcoma cells through regulation of Med1 and Med31 (show MED31 Proteins).

  3. MED1 is required for optimal PRDM16 (show PRDM16 Proteins)-induced Ucp1 (show UCP1 Proteins) expression

  4. no association between SCZ and the SNPs of VDR, suggesting that VDR is not a major gene for SCZ in Chinese Han population. However, our data indicate a potential involvement of VDR SNPs in the susceptibility of risperidone-treated patients to MetS

  5. hyperactivated ERK (show EPHB2 Proteins) and/or AKT (show AKT1 Proteins) signaling pathways promoted MED1 overexpression in prostate cancer cells.

  6. These results demonstrate a role for MED1 in mediating resistance to the pure anti-estrogen fulvestrant both in vitro and in vivo.

  7. multiple modes of the GATA1 (show GATA1 Proteins)-MED1 axis may help to fine-tune GATA1 (show GATA1 Proteins) function during GATA1 (show GATA1 Proteins)-mediated homeostasis events.

  8. Data concluded that those of VDR (show CYP27B1 Proteins) ff genotype may be regarded as "low responders" to vitamin D intake in terms of response of circulating 25(OH)D and certain inflammatory biomarkers.

  9. MiR (show MLXIP Proteins)-205 is an epigenetically regulated tumor suppressor that targets MED1.

  10. MED1 is recruited to the HER2 (show ERBB2 Proteins) gene and required for its expression.

Mouse (Murine) Mediator Complex Subunit 1 (MED1) interaction partners

  1. Med1 and Med12, two subunits of the mediator complex implicated in transcription initiation and long-range enhancer/promoter loop formation, are dynamically recruited to the IgH locus enhancers.

  2. We conclude that MED1 (show MBD4 Proteins) regulates the temporal progression of primary spermatocytes through meiosis, with its absence resulting in abbreviated pre-leptotene, leptotene, and zygotene stages, and a prolonged pachytene stage.

  3. These results demonstrate that Med1 (show MBD4 Proteins) is a master regulator in adult stem cells to govern epithelial cell fate

  4. The novel function of MED1 (show MBD4 Proteins) in keratinocytes.

  5. PRDM16 (show PRDM16 Proteins) deficiency in BAT (show BAAT Proteins) reduces MED1 (show MBD4 Proteins) binding at PRDM16 (show PRDM16 Proteins) target sites and causes a fundamental change in chromatin architecture at key brown fat-selective genes

  6. Collectively, these observations strongly suggest that MED1 (show MBD4 Proteins) has an important affect on mitochondrial function.

  7. Clk2 (show CLK2 Proteins) phosphorylation of PGC-1alpha disrupts its interaction with Mediator subunit 1, which leads to a suppression of PGC-1alpha activation of peroxisome proliferator-activated receptor alpha (show PPARA Proteins) target genes in fatty acid oxidation and ketogenesis.

  8. hyperactivated ERK (show EPHB2 Proteins) and/or AKT (show AKT1 Proteins) signaling pathways promoted MED1 (show MBD4 Proteins) overexpression in prostate cancer cells.

  9. Med1 (show MBD4 Proteins) phosphorylation by its association with AMPK (show PRKAA1 Proteins) regulates liver cell proliferation and fatty acid oxidation, most likely as a downstream effector of PPARalpha (show PPARA Proteins) and AMPK (show PRKAA1 Proteins)

  10. Tshb (show TSHB Proteins) gene transcription was attenuated in MED1 (show MBD4 Proteins) mutant mice in which the nuclear receptor-binding ability of MED1 (show MBD4 Proteins) was specifically disrupted.

MED1 Protein Profile

Protein Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Alternative names and synonyms associated with MED1

  • mediator complex subunit 1 (MED1)
  • mediator complex subunit 1 (med1)
  • Mediator complex subunit 1 (MED1)
  • mediator complex subunit 1 (Med1)
  • mediator of RNA polymerase II transcription subunit 1 (med1)
  • AI480703 protein
  • CG7162 protein
  • CRSP1 protein
  • CRSP200 protein
  • CRSP210 protein
  • Dmel\\CG7162 protein
  • DRIP205 protein
  • DRIP230 protein
  • dTRAP220 protein
  • l11Jus15 protein
  • Med1 protein
  • Med1/SOP3/TRAP220 protein
  • nbr1 protein
  • PBP protein
  • Pparbp protein
  • PPARGBP protein
  • RB18A protein
  • RGD1559552 protein
  • TRAP220 protein
  • TRIP2 protein

Protein level used designations for MED1

PPAR binding protein , mediator complex subunit 1 , peroxisome proliferator-activated receptor binding protein , membrane component, chromosome 17, surface marker 2 , CG7162-PA , CG7162-PB , CG7162-PC , MED1-PA , MED1-PB , MED1-PC , mediator , ARC205 , PPAR-binding protein , PPARG binding protein , TR-interacting protein 2 , TRIP-2 , activator-recruited cofactor 205 kDa component , mediator of RNA polymerase II transcription subunit 1 , p53 regulatory protein RB18A , peroxisome proliferator-activated receptor-binding protein , thyroid hormone receptor-associated protein complex 220 kDa component , thyroid hormone receptor-associated protein complex component TRAP220 , thyroid receptor interacting protein 2 , thyroid receptor-interacting protein 2 , vitamin D receptor-interacting protein 230 kD , vitamin D receptor-interacting protein complex component DRIP205 , Ppar binding protein , peroxisome proliferator activated receptor binding protein

GENE ID SPECIES
420004 Gallus gallus
454629 Pan troglodytes
480533 Canis lupus familiaris
779622 Xenopus (Silurana) tropicalis
40403 Drosophila melanogaster
5469 Homo sapiens
19014 Mus musculus
497991 Rattus norvegicus
101102404 Ovis aries
432291 Xenopus laevis
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