Browse our anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antibodies

On www.antibodies-online.com are 81 Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antibodies from 13 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 5, Group A, Member 1 Kits (19) and Nuclear Receptor Subfamily 5, Group A, Member 1 Proteins (6) and many more products for this protein. A total of 113 Nuclear Receptor Subfamily 5, Group A, Member 1 products are currently listed.
Synonyms:
Ad4bp, Ad4BP/SF-1, ELP, ELP-3, ff1a, ftz, Ftz-F1, FTZ1, Ftzf1, NR5A1, POF7, Sf-1, SF-1/Ad4BP, SF1, SPGF8, SRXY3, zFF1, zFF1A, zFF1B
list all antibodies Gene Name GeneID UniProt
NR5A1 2516 Q13285
NR5A1 26423 P33242
NR5A1 83826 P50569

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More Antibodies against Nuclear Receptor Subfamily 5, Group A, Member 1 Interaction Partners

Zebrafish Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. chemical inhibition of Nr5a2 function during hepatopancreas progenitor specification was sufficient to disrupt exocrine pancreas formation and enhance the size of the embryonic liver, suggesting that Nr5a2 regulates hepatic vs. pancreatic progenitor fate choice.

  2. ff1a functions in both slow and fast muscle morphogenesis in response to Hedgehog (show SHH Antibodies) signaling, and this function parallels the activity of another slow muscle gene, prox1 (show PROX1 Antibodies)

  3. The role of Sox9a in ff1a gene regulation and function was studied using sox9a morpholinos.

Human Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. Ten novel heterozygous NR5A1 mutations were identified in 46,XY DSD (show FADS1 Antibodies) patients, including five nonsynonymous variants (p.Gly26Glu, p.Thr29Arg, p.Trp302Cys, p.Ala340Val, p.Leu358Pro), four stop-gain variants (p.Tyr211*, p.Cys247*, p.Tyr404*, p.Cys412*), and one frameshift variant (p.Glu395del)

  2. we show that a specific recurrent heterozygous missense mutation (p.Arg92Trp) in the accessory DNA-binding region of NR5A1 is associated with variable degree of testis development in 46,XX children and adults from four unrelated families

  3. we review genetic data generated through large-scale sequencing approaches that are changing our view of how this system works, including the recently described recurrent NR5A1 p.R92W mutation associated with testis development in 46,XX children

  4. The NR5A1 p.Arg92Gln variant, which has thus far only been seen in a family with 46,XY Disorder of Sex Development, most likely contributes to the ovotesticular Disorder of Sex Development in this case.

  5. Data suggest that the first screening step diagnosis for pituitary adenoma was determined based upon immunohistochemical (IHC) scores for Pit-1 (show POU1F1 Antibodies), SF-1, and ACTH (show POMC Antibodies).

  6. We analysed a Pakistani cohort of patients with 46,XY disorders of sex development (DSD (show FADS1 Antibodies)), presenting with variable degrees of gonadal dysgenesis, for NR5A1 mutations. The study identified three mutations (p.Tyr03X, p.Glu07X and p.Gln299HisfsX386), of which two are novel, in these patients with 46,XY DSD (show FADS1 Antibodies).

  7. demonstrate aberrant expressions of SF-1 and LRH-1 (show NR5A2 Antibodies) in endometriotic granulosa-lutein cells

  8. this is the first report of the NR5A1 splice site mutation, which was proven to be deleterious by the RT-PCR method.

  9. SF1 SNPs are associated with serum uric acid levels in Chinese males and females.

  10. Describe microcystic stromal tumor as a distinctive ovarian sex cord-stromal neoplasm characterized by FOXL2 (show FOXL2 Antibodies), SF-1, WT-1 (show WT1 Antibodies), Cyclin D1 (show CCND1 Antibodies), and beta-catenin (show CTNNB1 Antibodies) nuclear expression and CTNNB1 (show CTNNB1 Antibodies) mutations.

Mouse (Murine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. Our data suggested that lipid accumulation in the Leydig cells of the 46,XY disorders of sex development phenotype with a steroidogenic factor 1 mutation is due, at least in part, to the suppression of steroidogenic acute regulatory protein (show STAR Antibodies) and CYP11A1 (show CYP11A1 Antibodies), and a resulting increase in unmetabolized cholesterol.

  2. SF-1 (show SF1 Antibodies) is needed for proper development of fetal and adult Leydig cells but with distinct primary functions

  3. NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and beta-catenin (show CTNNB1 Antibodies) accumulation

  4. The results suggest that gonadal steroids do not influence the production of neurosteroids in the fetal brain, nor does SF-1 (show SF1 Antibodies) play a major role in the regulation of steroidogenic enzyme expression in the brain.

  5. MiR (show MLXIP Antibodies)-383 promoted the expression of miR (show MLXIP Antibodies)-320 which regulated granulosa cell functions by targeting E2F1 (show E2F1 Antibodies) and SF-1 (show SF1 Antibodies) proteins.

  6. Data indicate that genetic ablation of the Vanin-1 (Vnn1 (show VNN1 Antibodies)) gene in SF-1 (NR5A1) transgenic mice significantly reduced the severity of neoplastic lesions in the adrenal cortex.

  7. FOXL2 (show FOXL2 Antibodies) negatively regulates Sf1 (show SF1 Antibodies) expression by antagonizing WT1 (show WT1 Antibodies)-KTS during early ovarian development in mice

  8. we provide the evidence that the acidic residue (E199) located downstream from the core consensus SUMO site of NR5A1 is, at least in part, required for SUMOylation of NR5A1 and for its mediated target gene and protein expression.

  9. Data suggest that the regulation of StAR by transcription factors including SF-1 (show SF1 Antibodies), GATA-4 (show GATA4 Antibodies) and C/EBP-beta (show CEBPB Antibodies) maybe critical mechanism involved in low-dose MBP (show MBP Antibodies)-stimulated steroidogenesis.

  10. Data indicate that reduced numbers of steroidogenic factor 1-positive (SF1 (show SF1 Antibodies)(+)) progenitor cells and increased fetal Leydig cells (FLCs), and increased hedgehog (show SHH Antibodies) (Hh) activation led to decreased adult Leydig cells (ALCs) populations.

Pig (Porcine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. NR5A1 variations influence meat color in a hypothalamus-pituitary-adrenal axis independent manner

Cow (Bovine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. These results indicate that PCBs impair the secretory function of ovarian steroidogenic cells by disrupting steroidogenesis and increasing OT secretion, and the receptor SF-1 appears to be essentially involved in these processes.

  2. The SF-1 and beta-catenin pathway convergence on StarD7 expression may have important implications in the phospholipid uptake and transport, contributing to the normal trophoblast development.

  3. The role of the NR5A1 activating functions AF-1 & AF (show Psmd4 Antibodies)-2 was studied in luteinizing bovine theca cells. The regulation of the 3 NR5A1-controlled genes CYPA11, STAR, & INSL3 (show INSL3 Antibodies) apparently is not dependent on NR5A1 activating functions AF-1 (show Psmd4 Antibodies) or AF-2.

  4. Involvement of Ad4BP/SF-1, DAX-1 (show NR0B1 Antibodies), and COUP-TFII (show NR2F2 Antibodies) transcription factor on steroid production and luteinization in ovarian theca cells.

  5. GATA4 (show GATA4 Antibodies) and GATA6 (show GATA6 Antibodies) mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 (show GATA6 Antibodies) showed a marked decrease at the regressed luteal stage, like NR5A1, NR5A2 (show NR5A2 Antibodies), and the other steroidogenic markers.

Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1)

  • nuclear receptor subfamily 5, group A, member 2 (nr5a2) antibody
  • nuclear receptor subfamily 5, group A, member 1 (NR5A1) antibody
  • nuclear receptor subfamily 5, group A, member 1 (nr5a1) antibody
  • steroidogenic factor 1 (SF-1) antibody
  • nuclear receptor subfamily 5, group A, member 1 (Nr5a1) antibody
  • steroidogenic factor 1-like (LOC100738392) antibody
  • Ad4bp antibody
  • Ad4BP/SF-1 antibody
  • ELP antibody
  • ELP-3 antibody
  • ff1a antibody
  • ftz antibody
  • Ftz-F1 antibody
  • FTZ1 antibody
  • Ftzf1 antibody
  • NR5A1 antibody
  • POF7 antibody
  • Sf-1 antibody
  • SF-1/Ad4BP antibody
  • SF1 antibody
  • SPGF8 antibody
  • SRXY3 antibody
  • zFF1 antibody
  • zFF1A antibody
  • zFF1B antibody

Protein level used designations for NR5A1

LRH1 , fushi tarazu , nuclear receptor subfamily 5 group A member 2 , steroidogenic factor 1 , nuclear receptor subfamily 5, group A, member 1 , steroidgenic factor 1 , steroidogenic factor-1 , STF-1 , adrenal 4 binding protein , adrenal 4-binding protein , fushi tarazu factor homolog 1 , nuclear receptor AdBP4 , steroid hormone receptor Ad4BP , steroidogenic factor 1 nuclear receptor , embryonal LTR-binding protein , embryonal long terminal repeat-binding protein , fushi tarazu 1 factor homolog , steroid hydroxylase positive regulator , nuclear receptor subfamily 5 group A member 1 , steroidogenic factor-1 SF-1

GENE ID SPECIES
30749 Danio rerio
751778 Taeniopygia guttata
100271747 Xenopus (Silurana) tropicalis
100534561 Oreochromis niloticus
2516 Homo sapiens
26423 Mus musculus
83826 Rattus norvegicus
609642 Canis lupus familiaris
397368 Sus scrofa
281948 Bos taurus
395960 Gallus gallus
100049145 Xenopus laevis
100033902 Equus caballus
443464 Ovis aries
100738392 Sus scrofa
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