Browse our anti-NR5A2 + LRH1 (NR5A2) Antibodies

Full name:
anti-Nuclear Receptor Subfamily 5, Group A, Member 2 Antibodies (NR5A2)
On www.antibodies-online.com are 92 Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2) Antibodies from 19 different suppliers available. Additionally we are shipping NR5A2 + LRH1 Kits (12) and NR5A2 + LRH1 Proteins (7) and many more products for this protein. A total of 119 NR5A2 + LRH1 products are currently listed.
Synonyms:
AU020803, B1F, B1F2, CPF, D1Ertd308e, ff1r, Ftf, FTZ-F1, FTZ-F1beta, hb1f, hB1F-2, Lrh-1, LRH1, NR5A2, UF2-H3B, xff1ra, xff1rashort, xFF1rB
list all antibodies Gene Name GeneID UniProt
NR5A2 2494 O00482
NR5A2 26424 P45448
NR5A2 60349 Q9QWM1

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Most Popular Reactivities for anti-NR5A2 + LRH1 (NR5A2) Antibodies

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anti-Human NR5A2 + LRH1 Antibodies:

anti-Mouse (Murine) NR5A2 + LRH1 Antibodies:

anti-Rat (Rattus) NR5A2 + LRH1 Antibodies:

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Top referenced anti-NR5A2 + LRH1 Antibodies

  1. Human Polyclonal NR5A2 + LRH1 Primary Antibody for ICFC - ABIN2666143 : Li, Xie, Kong, Wu, Zhu, Wang: Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which binds and activates enhancer II of hepatitis B virus. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for 2666143

  2. Cow (Bovine) Polyclonal NR5A2 + LRH1 Primary Antibody for WB - ABIN2780550 : Lee, Choi, Chua, Park, Moore: Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Polyclonal NR5A2 + LRH1 Primary Antibody for ELISA, WB - ABIN4331473 : Yumoto, Nguyen, Sablin, Baxter, Webb, Fletterick: Structural basis of coactivation of liver receptor homolog-1 by β-catenin. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  4. Human Polyclonal NR5A2 + LRH1 Primary Antibody for ICC, IF - ABIN4331468 : Benod, Vinogradova, Jouravel, Kim, Fletterick, Sablin: Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)

More Antibodies against NR5A2 + LRH1 Interaction Partners

Human Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2) interaction partners

  1. miR (show MLXIP Antibodies)-27b-3p levels were found to be significantly negatively correlated with both NR5A2 and CREB1 (show CREB1 Antibodies) levels in breast cancer tissues.

  2. The fusion transcript NR5A2-KLHL29FT was identified in normal and cancerous colonic epithelia. It is due to an uncharacterized polymorphic germline insertion of the NR5A2 sequence from chromosome 1 into the KLHL29 locus at chromosome 2, rather than a chromosomal rearrangement. NR5A2-KLH29FT expression levels were significantly lower in colon cancers than in matched normal colonic epithelia.

  3. Additionally, the authors solved the structure of the human LRH-1 DNA-binding domain bound to a DR0 motif located within the Oct4 (show POU5F1 Antibodies) promoter.

  4. miR (show MLXIP Antibodies)-376c inhibits non-small-cell lung cancer cell growth and invasion by targeting LRH-1

  5. The first crystal structure of the LRH-1-PGC1alpha complex , which depicts hydrophobic contacts is identified and described.

  6. The dramatic repositioning is influenced by a differential ability to establish stable face-to-face pi-pi-stacking with the LRH-1 residue His-390, as well as by a novel polar interaction mediated by the RJW100 hydroxyl group. The differing binding modes result in distinct mechanisms of action for the two agonists.

  7. The role of NR5A2 in regulating pancreatic cancer stem cell properties and epithelial-mesenchymal transition of pancreatic carcinoma cells

  8. demonstrate aberrant expressions of SF-1 (show NR5A1 Antibodies) and LRH-1 in endometriotic granulosa-lutein cells

  9. Down-regulation of MicroRNA-381 promotes cell proliferation and invasion in colon cancer cells through up-regulation of LRH-1.

  10. The present study indicates that miR (show MLXIP Antibodies)-381 may be a novel tumor suppressor that blocks HCC (show FAM126A Antibodies) growth and invasion by targeting LRH-1.

Mouse (Murine) Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2) interaction partners

  1. results suggest that Sod2 (show SOD2 Antibodies) is a target gene of LRH-1, and that LRH-1 agonists can mediate a reduction in ROS (show ROS1 Antibodies) production and oxidative stress driven by an excess of fatty acids, as exhibited in nonalcoholic fatty liver disease

  2. These findings suggest that compromised SUMOylation of LRH-1 promotes the development of nonalcoholic fatty liver disease under lipogenic conditions through regulation of OSBPL3 (show OSBPL3 Antibodies).

  3. these data show for the first time LRH-1 expression in T cells, its role in FASLG (show FASL Antibodies) transcription and the potential of pharmacological inhibition of LRH-1 in the treatment of FasL (show FASL Antibodies)-mediated immunopathologies

  4. highlight the importance of LRH-1 in coordinating glutamine (show GFPT1 Antibodies)-induced metabolism and signaling to promote hepatocellular carcinogenesis.

  5. Mice carrying a mutation on lysine 289 of LRH-1 (Lrh1 K289R mice) display reduced LRH-1 SUMOylation and increased expression of genes regulating cholesterol transport.

  6. Results identify LRH-1 as a critical component of the anti-inflammatory and fungicidal response of alternatively activated macrophages that acts upstream from the IL-13 (show IL13 Antibodies)-induced 15-HETE/PPARgamma (show PPARG Antibodies) axis.

  7. The authors conclude that LRH-1 initiates a novel pathway of endoplasmic reticulum stress resolution that is independent of the unfolded protein response, yet equivalently required.

  8. study demonstrates for the first time that LRH-1 has a CRT (show SLC6A8 Antibodies)-dependent NES (show NES Antibodies) which is not only required for cytoplasmic trafficking, but also essential for correct protein folding to avoid misfolding-induced aggregation.

  9. Heterozygous gene deletion of LRH-1 causes body weight gains without any apparent worsening of glucose and lipid metabolism.

  10. NR5A2 has a role in controlling aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

Cow (Bovine) Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2) interaction partners

  1. GATA4 (show GATA4 Antibodies) and GATA6 (show GATA6 Antibodies) mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 (show GATA6 Antibodies) showed a marked decrease at the regressed luteal stage, like NR5A1 (show NR5A1 Antibodies), NR5A2, and the other steroidogenic markers.

  2. NR5A2 (LRH-1, SF2 (show SRSF1 Antibodies)) mRNA is upregulated in granulosa cells of dominant and hCG (show CGA Antibodies)-induced ovulatory ovarian follicles.

NR5A2 + LRH1 (NR5A2) Antigen Profile

Antigen Summary

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Alternative names and synonyms associated with NR5A2 + LRH1 (NR5A2)

  • nuclear receptor subfamily 5, group A, member 2 (nr5a2) antibody
  • nuclear receptor subfamily 5, group A, member 2 (NR5A2) antibody
  • nuclear receptor subfamily 5, group A, member 2 (nr5a2-b) antibody
  • nuclear receptor subfamily 5, group A, member 2 (Nr5a2) antibody
  • AU020803 antibody
  • B1F antibody
  • B1F2 antibody
  • CPF antibody
  • D1Ertd308e antibody
  • ff1r antibody
  • Ftf antibody
  • FTZ-F1 antibody
  • FTZ-F1beta antibody
  • hb1f antibody
  • hB1F-2 antibody
  • Lrh-1 antibody
  • LRH1 antibody
  • NR5A2 antibody
  • UF2-H3B antibody
  • xff1ra antibody
  • xff1rashort antibody
  • xFF1rB antibody

Protein level used designations for NR5A2

nuclear receptor subfamily 5, group A, member 2 , Ftz-F1-related orphan receptor A , FTZ-F1-related nuclear orphan receptor , Ftz-F1-related orphan receptor , liver receptor-like protein 1 , CYP7A promoter-binding factor , alpha-1-fetoprotein transcription factor , b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus , fetoprotein-alpha 1 (AFP) transcription factor , hepatocytic transcription factor , liver nuclear receptor homolog-1 variant 2 , liver receptor homolog 1 , liver receptor homolog-1 , nuclear receptor NR5A2 , nuclear receptor subfamily 5 group A member 2 , Ftz-F1-related orphan receptor B , FTF/LRH-1 , OR2.0 , fetoprotein transcription factor , FTZ-F1 beta , FTZ-F1 beta2 protein

GENE ID SPECIES
397700 Xenopus laevis
469631 Pan troglodytes
496513 Xenopus (Silurana) tropicalis
100027003 Monodelphis domestica
2494 Homo sapiens
399449 Xenopus laevis
395961 Gallus gallus
26424 Mus musculus
60349 Rattus norvegicus
541305 Bos taurus
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