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anti-Mouse (Murine) BAX antibody for Flow Cytometry

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX
  • bax
  • bax-A
  • BAX-ALPHA
  • BCL2L4
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • xBax
  • xlbax
Reactivity
Human, Mouse (Murine), Rat (Rattus)
489
165
153
65
23
22
13
9
3
2
2
2
1
1
Host
Rabbit
316
212
4
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
14
13
10
8
7
7
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
Application
Flow Cytometry (FACS)
387
201
152
144
137
128
97
65
55
34
6
6
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2664009
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010463598 ABIN2666260 FACS Mouse IgG1 kappa Log in to see 6A7 6
0.0010463598 ABIN2666262 FACS Mouse IgG1 kappa Log in to see 5B7 5
0.0010463598 ABIN2666261 FACS Mouse IgG1 kappa Log in to see 6A7 6
0.0010463598 ABIN2666263 FACS Mouse IgG1 kappa Log in to see 5B7 5
0.0010463598 ABIN2736349 FACS IF IP IHC WB Rabbit IgG Log in to see Polyclonal
0.0010463598 ABIN2962011 FACS IHC (p) WB Rabbit Log in to see Polyclonal
0.0010463598 ABIN2664008 FACS Rabbit IgG Log in to see Polyclonal
0.0010463598 ABIN2973727 ICC FACS IF IP IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-BAX antibody for Flow Cytometry

Similar anti-BAX Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 354 Antibodies 107 Antibodies 91 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 113 Antibodies 49 Antibodies 32 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 135 Antibodies 26 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 144 Antibodies 59 Antibodies 56 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 50 Antibodies 7 Antibodies 4 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(489), (165), (153), (65), (23), (22), (13), (9), (3), (2), (2), (2), (1), (1)
Host Rabbit
(316), (212), (4)
Clonality (Clone)
Polyclonal   ( )
Conjugate This BAX antibody is un-conjugated
(19), (14), (13), (10), (8), (7), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Application Flow Cytometry (FACS)
(387), (201), (152), (144), (137), (128), (97), (65), (55), (34), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX Antibody (ABIN2664009) Images
Purification This antibody was purified by affinity chromatography.
Clone Poly6251
Isotype IgG

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX Antibody (ABIN2664009) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background Bax is a 21 kD pro-apoptotic protien known to regulate apoptosis. Bax is found in the cytoplasm, mitochondria, and nucleus and is highly expressed in hematopoietic stem cells, the ovary, and in the lymph node. Bax binds the anti-apoptotic protein Bcl-2 as a heterodimer or forms homodimers. The relative levels of pro-apoptotic proteins such as Bax and anti-apoptotic proteins such as Bcl-2 determines whether cell death will occur following an apoptotic stimulus. Bax accelerates the opening of mitochondrial VDAC altering membrane potential and allowing cytochrome c to pass out of the mitochondria into the cytosol to initiate downstream caspase activation. p53 can transcriptionally activate the Bax gene to induce apoptosis. Bax has been shown to be mutated in some human cancers. The Poly6251 antibody has been reported to be useful for Western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat Bax protein.
Research Area Cancer, Apoptosis/Necrosis
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX Antibody (ABIN2664009) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX Antibody (ABIN2664009) Images back to top
Format Liquid
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % gelatin.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-BAX Antibody (ABIN2664009)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Background publications

Hayashida, Kajino, Hattori, Wallace, Morrison, Greene, Sugimoto: "MDM2 regulates a novel form of incomplete neoplastic transformation of Theileria parva infected lymphocytes." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 228-38, 2013

Leroy, Tricot, Lacour, Grynberg: "Protective effect of eicosapentaenoic acid on palmitate-induced apoptosis in neonatal cardiomyocytes." in: Biochimica et biophysica acta, Vol. 1781, Issue 11-12, pp. 685-93, 2008

Ma, Hossain, Chow, Arshad, Battson, Sanders, Mehmet, Edwards, Franks, Maze: "Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia." in: Annals of neurology, Vol. 58, Issue 2, pp. 182-93, 2005

Kim, Seong, Kim: "Enhancement of tumor response by farnesyltransferase inhibitor in C3H/HeJ hepatocarcinoma." in: Annals of the New York Academy of Sciences, Vol. 1030, pp. 95-102, 2005

You, Seo, Chung, Kim: "A novel metalloprotease from Gloydius halys venom induces endothelial cell apoptosis through its protease and disintegrin-like domains." in: Journal of biochemistry, Vol. 134, Issue 5, pp. 739-49, 2003

LeBlanc, Lawrence, Varfolomeev, Totpal, Morlan, Schow, Fong, Schwall, Sinicropi, Ashkenazi: "Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax." in: Nature medicine, Vol. 8, Issue 3, pp. 274-81, 2002

Marzo, Brenner, Zamzami, Jürgensmeier, Susin, Vieira, Prévost, Xie, Matsuyama, Reed, Kroemer: "Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis." in: Science (New York, N.Y.), Vol. 281, Issue 5385, pp. 2027-31, 1998

Miyashita, Reed: "Tumor suppressor p53 is a direct transcriptional activator of the human bax gene." in: Cell, Vol. 80, Issue 2, pp. 293-9, 1995

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX Antibody (ABIN2664009) back to top
Supplier Images
Western Blotting (WB) image for anti-BAX antibody (BCL2-Associated X Protein) (ABIN2664009) anti-BCL2-Associated X Protein (BAX) antibody