anti-Non-Human Primate CDKN1A antibody for ELISA

Recommended CDKN1A Antibody (supplied by: Log in to see )

Antigen
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
  • p21
  • cip1
  • p16Xic2
  • CCND1
  • sdi1
  • waf1
  • cap20
  • cdkn1
  • mda-6
  • p21cip1
  • CDKN1A
  • si:ch1073-48m5.2
  • Cip1
  • UV96
  • Waf1
  • CAP20
  • CDKN1
  • CIP1
  • MDA-6
  • P21
  • SDI1
  • WAF1
  • p21CIP1
  • CDKI
  • Cdkn1
  • mda6
  • p21Cip1
  • p21WAF
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • cyclin-dependent kinase inhibitor 1
  • cyclin-dependent kinase inhibitor 1A
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cdkn1a
  • cki1
  • CDKN1A
  • LOC100348489
  • Cdkn1a
Reactivity
Human, Non-Human Primate
590
184
124
30
23
9
6
5
4
2
1
1
1
1
1
1
1
Host
Mouse
318
312
3
1
Clonality
Monoclonal
Conjugate
This CDKN1A antibody is un-conjugated
33
32
32
23
17
17
15
15
13
13
10
10
10
10
10
10
10
8
8
7
7
7
6
4
4
4
4
4
4
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
358
223
195
166
153
141
67
62
59
53
30
15
7
7
6
2
1
1
Options
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Catalog No. ABIN94444
$ 254.10
Plus shipping costs $45.00

General

Antigen Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies
Reactivity Human, Non-Human Primate
(590), (184), (124), (30), (23), (9), (6), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(318), (312), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CDKN1A antibody is un-conjugated
(33), (32), (32), (23), (17), (17), (15), (15), (13), (13), (10), (10), (10), (10), (10), (10), (10), (8), (8), (7), (7), (7), (6), (4), (4), (4), (4), (4), (4)
Application Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(358), (223), (195), (166), (153), (141), (67), (62), (59), (53), (30), (15), (7), (7), (6), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-CDKN1A Antibody

Target Details CDKN1A Application Details Handling References for anti-CDKN1A antibody (ABIN94444) Images
Specificity The antibody WA-1 reacts with p21 protein (Waf1, Cip1, SDI 1), a 21 kDa tumour suppressor, which inhibits the activity of cyclin-dependent family kinases and of proliferating cell nuclear antigen.
Purification Purified from ascites by precipitation methods.
Purity > 95 % (by SDS-PAGE)
Immunogen Human p21 protein
Clone WA-1
Isotype IgG1

Target Details CDKN1A

Product Details anti-CDKN1A Antibody Application Details Handling References for anti-CDKN1A antibody (ABIN94444) Images back to top
Antigen
Alternative Name CDKN1A (CDKN1A Antibody Abstract)
Background The tumour suppressor p21Waf1 (Wild-type p53-Activated Fragment 1, also known as Cip1, Cdk interacting protein, or SDI 1) is a cyclin-dependent kinase (Cdk) inhibitor, which is expressed by involvement of p53, Egr-1, AP2, STATs or other transcription factors upon various stimuli resulting in cell cycle arrest. Through its N-terminal domain p21Waf1 inhibits Cdk activity, whereas through the C-terminal domain it inhibits the activity of PCNA (proliferating cell nuclear antigen) to activate DNA replication. Cytosolic location of p21 counteracts its inhibitory activities.
Pathways p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy

Application Details

Product Details anti-CDKN1A Antibody Target Details CDKN1A Handling References for anti-CDKN1A antibody (ABIN94444) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details References for anti-CDKN1A antibody (ABIN94444) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CDKN1A antibody (ABIN94444)

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Handling Images back to top
Background publications

Choi, Kim, Bae, Lim, Lee, Shin: "p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression." in: Cancer research, Vol. 68, Issue 5, pp. 1369-77, 2008

Keeshan, Cotter, McKenna: "Bcr-Abl upregulates cytosolic p21WAF-1/CIP-1 by a phosphoinositide-3-kinase (PI3K)-independent pathway." in: British journal of haematology, Vol. 123, Issue 1, pp. 34-44, 2003

Horký, Kuchtícková, Vojtesek, Kolár: "Induction of cell-cycle inhibitor p21 in rat ventricular myocytes during early postnatal transition from hyperplasia to hypertrophy." in: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 46, Issue 3, pp. 233-5, 1998

Waga, Hannon, Beach, Stillman: "The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA." in: Nature, Vol. 369, Issue 6481, pp. 574-8, 1994

Product cited in:

Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, 2000

Images

Product Details anti-CDKN1A Antibody Target Details CDKN1A Application Details Handling References for anti-CDKN1A antibody (ABIN94444) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody (ABIN94444) Immunohistochemistry staining of colon carcinoma (paraffin-embedded sections) with an...
Immunofluorescence (IF) image for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody (ABIN94444) Immunofluorescence staining of p21 in human primary fibroblasts using anti-p21 (; gre...