anti-Dog (Canine) FAS antibody for Immunohistochemistry (Frozen Sections)

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Reactivity
Baboon, Cynomolgus, Dog (Canine), Human, Pig (Porcine), Rhesus Monkey
647
116
101
21
14
10
5
5
3
3
2
2
2
1
Host
Mouse
421
305
29
5
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
73
65
51
29
15
8
8
8
6
6
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
348
326
211
149
113
86
60
54
52
46
25
18
12
9
7
7
6
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN2689460
Contact our Customer Service for availability and price in your country.

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Reactivity Baboon, Cynomolgus, Dog (Canine), Human, Pig (Porcine), Rhesus Monkey
(647), (116), (101), (21), (14), (10), (5), (5), (3), (3), (2), (2), (2), (1)
Host Mouse
(421), (305), (29), (5), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(73), (65), (51), (29), (15), (8), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
(348), (326), (211), (149), (113), (86), (60), (54), (52), (46), (25), (18), (12), (9), (7), (7), (6), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN2689460) Images
Brand BD Pharmingen™
Characteristics Reacts with the 45 kDa transmembrane cell surface Fas or Apo-1 antigen (designated CD95 at the Fifth HLDA Workshop) which is expressed on a variety of normal and neoplastic cells. The Fas/Apo-1 antigen is a polypeptide, which plays a role in the programmed sequence of events leading to cell death, termed apoptosis. The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines. Cross-linking with DX2 delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry DX2-induced apoptosis in Fas transfectant cells line P825/FASDT151 detected by DNA fragmentation analysis. Cells were incubated alone (lane 1), in the presence of mouse IgG1 (lane 2) or in the presence of DX2 at 10, 100 or 500 ng/mL (lanes 3, 4 and 5, respectively).

BD Pharmingen™ Purified Mouse Anti-Human CD95 - Purified - Clone DX2 - Isotype Mouse IgG1, κ - Reactivity Hu, Bab, Cyno, Dog, Pig, Rhe - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone DX2
Isotype IgG1, kappa

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN2689460) Images back to top
Antigen
Alternative Name CD95 (FAS Antibody Abstract)
Background Synonyms: Fas/APO-1
Research Area Immunology, Innate Immunity, Cytokines, CD Antigens, Apoptosis/Necrosis, Death Receptors, Cancer, Growth Factors, Surface Receptors of Immune Cells
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN2689460) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN2689460) Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-FAS antibody (ABIN2689460)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Cifone, De Maria, Roncaioli, Rippo, Azuma, Lanier, Santoni, Testi: "Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase." in: The Journal of experimental medicine, Vol. 180, Issue 4, pp. 1547-52, 1994

Itoh, Yonehara, Ishii, Yonehara, Mizushima, Sameshima, Hase, Seto, Nagata: "The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis." in: Cell, Vol. 66, Issue 2, pp. 233-43, 1991