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anti-Human TANK antibody for Immunofluorescence

Recommended TANK Antibody (supplied by: Log in to see )

Antigen
TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
  • C86182
  • E430026L09Rik
  • I-TRAF
  • ITRAF
  • TRAF2
Epitope
C-Term
24
20
15
13
10
5
4
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
116
38
36
5
3
2
1
1
1
1
Host
Rabbit
112
3
2
1
1
Clonality
Polyclonal
Conjugate
This TANK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
40
38
22
15
14
11
11
11
2
2
1
Supplier
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Catalog No. ABIN500867
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.32040194 ABIN500869 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 5
0.32040194 ABIN2707137 IC IF IHC WB Rabbit Center Log in to see Polyclonal
0.0010840179 ABIN272299 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
0.0010840179 ABIN2892225 IF IHC WB Rabbit Phe194 Log in to see Polyclonal
0.0010840179 ABIN3187169 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0010840179 ABIN2881896 IF Rabbit IgG Log in to see Polyclonal
0.0010840179 ABIN408307 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0010840179 ABIN2371453 IF IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
0.0010840179 ABIN4357804 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0010840179 ABIN4357805 ELISA ICC IF WB Rabbit N-Term Log in to see Polyclonal
0.0010840179 ABIN3017631 IF WB Rabbit Log in to see Polyclonal
0.0010840179 ABIN2969957 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal
0.0010840179 ABIN4357803 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
0.0010840179 ABIN3067714 ICC IF IHC WB Rabbit Center Log in to see Polyclonal

Top referenced anti-TANK antibody for Immunofluorescence

Similar anti-TANK Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 9 Antibodies 9 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 3 Antibodies
Immunofluorescence (IF) 5 Antibodies 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 11 Antibodies 13 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies 12 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 27 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
Epitope C-Term
(24), (20), (15), (13), (10), (5), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(116), (38), (36), (5), (3), (2), (1), (1), (1), (1)
Host Rabbit
(112), (3), (2), (1), (1)
Clonality
Polyclonal
Conjugate This TANK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(103), (40), (38), (22), (15), (14), (11), (11), (11), (2), (2), (1)
Pubmed 5 references available
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Product Details anti-TANK Antibody

Target Details TANK Application Details Handling References for anti-TANK Antibody (ABIN500867) Images
Specificity This antibody detects TANK / ITRAF at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Peptide Affinity Chromatography
Immunogen 14 amino acid peptide from near the carboxy terminus of Human TANK.
Isotype IgG

Target Details TANK

Product Details anti-TANK Antibody Application Details Handling References for anti-TANK Antibody (ABIN500867) Images back to top
Antigen
Alternative Name TANK / ITRAF (TANK Antibody Abstract)
Background TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. This activation of NF-kappaB occurs through an association with the kinases IKKepsilon and TBK1. More recently, it was shown that these proteins can then form a complex with NEMO, a protein that regulates the activity of the IkappaB complex. This suggests that in addition to the possibility that TBK1 and IKKepsilon activate the IKKs, the association with the IKK complex may help these kinases modulate other functions, such as the transactivation potential of NF-kappaB proteins. At least two isoforms of TANK are known to exist.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2
Gene ID 10010
NCBI Accession NP_004171
Pathways p53 Signaling, TLR Signaling

Application Details

Product Details anti-TANK Antibody Target Details TANK Handling References for anti-TANK Antibody (ABIN500867) Images back to top
Application Notes ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TANK Antibody Target Details TANK Application Details References for anti-TANK Antibody (ABIN500867) Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-TANK Antibody (ABIN500867)

Product Details anti-TANK Antibody Target Details TANK Application Details Handling Images back to top
Background publications

Rao, Kadesch: "The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells." in: Molecular and cellular biology, Vol. 23, Issue 18, pp. 6694-701, 2003

Chariot, Leonardi, Muller, Bonif, Brown, Siebenlist: "Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases." in: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 37029-36, 2002

Pomerantz, Baltimore: "NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase." in: The EMBO journal, Vol. 18, Issue 23, pp. 6694-704, 2000

Cheng, Baltimore: "TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation." in: Genes & development, Vol. 10, Issue 8, pp. 963-73, 1996

Rothe, Xiong, Shu, Williamson, Goddard, Goeddel: "I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8241-6, 1996

Images

Product Details anti-TANK Antibody Target Details TANK Application Details Handling References for anti-TANK Antibody (ABIN500867) back to top
Supplier Images
Immunofluorescence (IF) image for anti-TANK antibody (TRAF Family Member-Associated NFKB Activator) (C-Term) (ABIN500867) Immunofluorescence of TANK in Rat Spleen cells with TANK antibody at 20 µg/ml.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-TANK antibody (TRAF Family Member-Associated NFKB Activator) (C-Term) (ABIN500867) Immunohistochemistry of TANK in rat spleen tissue with this product at 10 μg/ml.
Western Blotting (WB) image for anti-TANK antibody (TRAF Family Member-Associated NFKB Activator) (C-Term) (ABIN500867) Western blot analysis of TANK in Daudi cell lysate with this product at (A) 0.5, (B) ...