anti-Rat (Rattus) TANK antibody for Immunofluorescence

Recommended TANK Antibody (supplied by: Log in to see )

Antigen
TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
  • C86182
  • E430026L09Rik
  • I-TRAF
  • ITRAF
  • TRAF2
  • TRAF family member-associated NFKB activator
  • TRAF family member-associated Nf-kappa B activator
  • TANK
  • Tank
Reactivity
Human, Mouse (Murine), Rat (Rattus)
118
47
43
11
7
6
5
5
4
4
2
2
1
Host
Rabbit
112
3
2
1
1
Clonality
Polyclonal
Conjugate
This TANK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
105
44
35
24
16
14
13
13
9
3
2
2
1
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Catalog No. ABIN272299
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN3187169 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN5555293 EIA IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN408307 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2892225 IF IHC WB Rabbit Phe194 Log in to see Polyclonal
1 ABIN4357804 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Similar anti-TANK Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 9 Antibodies 9 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 3 Antibodies
Immunofluorescence (IF) 6 Antibodies 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 14 Antibodies 16 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 32 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies

General

Antigen TRAF Family Member-Associated NFKB Activator (TANK) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(118), (47), (43), (11), (7), (6), (5), (5), (4), (4), (2), (2), (1)
Host Rabbit
(112), (3), (2), (1), (1)
Clonality
Polyclonal
Conjugate This TANK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(105), (44), (35), (24), (16), (14), (13), (13), (9), (3), (2), (2), (1)
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Product Details anti-TANK Antibody

Target Details TANK Application Details Handling Images
Specificity This antibody detects endogenous levels of TANK protein. (region surrounding Phe194)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details TANK

Product Details anti-TANK Antibody Application Details Handling Images back to top
Antigen
Alternative Name TANK / ITRAF (TANK Antibody Abstract)
Background The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine- rich extracellular domains. Members of this family include TNF-RI and -RII, FAS, OX40, CD27, CD30 and CD40. Ligands for these receptors can be small, secreted proteins such as TNF, or type II integral membrane proteins, such as the CD40 ligand, CD40L. While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, stimulation of cells with either TNF or soluble CD40L has been shown to induce the nuclear translocation of NFκB. Members of the TRAF family associate with activated TNF-R and CD40 and have been implicated in this process. The discovery of a novel protein, designated TANK, has shed light on the means by which TRAF activation of NFkB occurs. TANK is not only capable of binding to all three TRAFs, but also of synergizing with TRAF2 to activate the NFκB signaling cascade. TANK contains a regulatory carboxy terminal domain that maintains its inactivity in unstimulated cells. Upon its association with TRAF2, the inhibitory effect of this domain is overcome.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2
Molecular Weight approx. 48 kDa
Gene ID 10010
NCBI Accession NP_001186064
UniProt Q92844
Pathways p53 Signaling, TLR Signaling, Activation of Innate immune Response

Application Details

Product Details anti-TANK Antibody Target Details TANK Handling Images back to top
Application Notes ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TANK Antibody Target Details TANK Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-TANK Antibody Target Details TANK Application Details Handling back to top
Supplier Images
 image for anti-TANK antibody (TRAF Family Member-Associated NFKB Activator) (ABIN272299) anti-TRAF Family Member-Associated NFKB Activator (TANK) antibody