Caspase 12 (CASP12) (N-Term) Peptide

Details for Product No. ABIN1382069
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Protein Name
Synonyms Caspase-12
Protein Region
Mouse (Murine)
(1), (3)
Blocking Peptide (BP)
Pubmed 3 references available
Quantity 0.05 mg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Characteristics 16 amino amino terminus of mouse Caspase-12.
Alternative Name Caspase-12
Research Area Apoptosis/Necrosis
Application Notes Caspase-12 peptide is used for blocking the. activity of caspase-12.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications McConnell, Vertino: "Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1." in: Cancer research, Vol. 60, Issue 22, pp. 6243-7, 2000 (PubMed).

Conway, McConnell, Bowring et al.: "TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers." in: Cancer research, Vol. 60, Issue 22, pp. 6236-42, 2000 (PubMed).

Nakagawa, Zhu, Morishima et al.: "Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta." in: Nature, Vol. 403, Issue 6765, pp. 98-103, 2000 (PubMed).

Catalog No. ABIN1382069
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