CD8b Molecule (CD8B) Peptide
CD8B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CD8B products
- CD8B (CD8b Molecule (CD8B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD8B antibody (Catalog #: ARP42204_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Synonyms
- Cd8b Peptide, Ly-3 Peptide, Ly-C Peptide, Lyt-3 Peptide, CD8B1 Peptide, LEU2 Peptide, LY3 Peptide, LYT3 Peptide, P37 Peptide, Cd8b1 Peptide, CD8b molecule Peptide, CD8 antigen, beta chain 1 Peptide, Cd8b Peptide, CD8B Peptide, Cd8b1 Peptide
- Background
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Alias Symbols: CD8B, LYT3, Leu2, Ly3, LY3, P37, LEU2, CD8B1
Protein Interaction Partner: CD3D,CD8A,CD8B,ST3GAL4,CD8A,LCK
Protein Size: 246 - Molecular Weight
- 27 kDa
- Gene ID
- 926
- NCBI Accession
- NM_172099, NP_742097
- UniProt
- Q53QL8
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