CD8B Products
(CD8b Molecule (CD8B))
Categories
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010].
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Featured CD8B Categories
CD8B Antibodies
High quality antibodies with extensive validation data.
CD8B ELISA Kits
Reliable ELISA kits for a wide range of species.
CD8B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD8B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7073405
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
FACS, WB, IP, IHC (fro)
Validations
- (9)
- (2)
Cat. No.
ABIN609653
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Rat
Application
FACS
Validations
- (8)
- (2)
Cat. No.
ABIN2749076
Quantity
0.1 mg
Datasheet
Datasheet
Recommended CD8B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954540
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730451
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1160710
Quantity
96 tests
Datasheet
Datasheet
Recommended CD8B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348730
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348728
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7319847
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CD8B products
: "Prenatal stress, anxiety and depression alter transcripts, proteins and pathways associated with immune responses at the maternal-fetal interface†." in: Biology of reproduction, Vol. 106, Issue 3, pp. 449-462, (2022) (PubMed).: "B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract." in: Scientific reports, Vol. 7, pp. 45090, (2018) (PubMed).
: "Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus." in: Veterinary microbiology, Vol. 164, Issue 1-2, pp. 46-59, (2013) (PubMed).
: "Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins." in: Journal of virology, Vol. 86, Issue 1, pp. 36-48, (2012) (PubMed).
: "In vitro assessment of the feline cell-mediated immune response against feline panleukopeniavirus, calicivirus and felid herpesvirus 1 using 5-bromo-2'-deoxyuridine labeling." in: Veterinary immunology and immunopathology, Vol. 146, Issue 2, pp. 177-84, (2012) (PubMed).
: "Natural killer cells: frequency, phenotype and function in healthy cats." in: Veterinary immunology and immunopathology, Vol. 150, Issue 1-2, pp. 69-78, (2012) (PubMed).
: "Flow cytometric assessment of chicken T cell-mediated immune responses after Newcastle disease virus vaccination and challenge." in: Vaccine, (2010) (PubMed).
: "Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells." in: Journal of translational medicine, Vol. 8, pp. 23, (2010) (PubMed).
: "Significant change in ZAP-70 expression during the course of chronic lymphocytic leukemia." in: European journal of haematology, Vol. 84, Issue 6, pp. 513-7, (2010) (PubMed).
: "Phenotyping, functional characterization, and developmental changes in canine intestinal intraepithelial lymphocytes." in: Veterinary research, Vol. 40, Issue 6, pp. 58, (2009) (PubMed).
Synonyms and alternative names related to CD8B
CD8b molecule (Cd8b), CD8b molecule (CD8B), CD8 antigen, beta chain 1 (Cd8b1), Cd8b, CD8B1, Cd8b1, LEU2, Ly-3, Ly-C, LY3, Lyt-3, LYT3, P37Protein level used designations for CD8B
- CD8 beta
- CD8 beta-2
- T-cell surface glycoprotein CD8 beta chain
- CD8 antigen beta polypeptide
- T-cell membrane glycoprotein Ly-3
- T-cell surface glycoprotein Lyt-3
- lymphocyte antigen 3
- CD8 antigen, beta polypeptide 1 (p37)
- T lymphocyte surface glycoprotein beta chain
- CD8 antigen 37 kDa chain
- CD8 antigen beta-chain
- CD8 antigen, beta chain
- CD8 antigen, beta-chain
- OX-8 membrane antigen
- CD8 beta chain
- CD8 antigen, beta polypeptide
- CD8b antigen
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