Diaphanous Homolog 1 (Drosophila) (DIAPH1) (C-Term) Peptide

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Protein Name
  • DIAPH1
  • dia1
  • drf1
  • dfna1
  • diap1
  • lfhl1
  • DIAPH2
  • Diap1
  • D18Wsu154e
  • Dia1
  • Diaph1
  • Drf1
  • mKIAA4062
  • p140mDia
  • DFNA1
  • DIA1
  • DRF1
  • LFHL1
  • hDIA1
  • diaphanous homolog 1 (Drosophila)
  • diaphanous-related formin 1
  • DIAPH1
  • diaph1
  • Diaph1
  • Diap1
Protein Region
C-Term
Origin
Human
3
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-DIAPH1 antibody (Diaphanous Homolog 1 (Drosophila)) (C-Term) (ABIN2789663)
Sequence TGVMDSLLEA LQSGAAFRRK RGPRQANRKA GCAVTSLLAS ELTKDDAMAA
Characteristics This is a synthetic peptide designed for use in combination with anti-DIAPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alias Symbols: DFNA1, DIA1, DRF1, FLJ25265, LFHL1, hDIA1

Protein Interaction Partner: CENPA,PKD2,BAIAP2,CDC7,CENPA,PAX6,PKD2,PRPF40A,RAC1,RHOA,RHOC,XPO6,APBB1,GAS7,NEDD4,PRPF40A,RHOA,SRGAP2,TCERG1,UBC,WBP4,XPO6

Protein Size: 1272
Molecular Weight 141 kDa
Gene ID 1729
NCBI Accession NM_005219, NP_005210
UniProt O60610
Research Area Signaling, Microfilaments, Cytoskeleton
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.