Eukaryotic Translation Initiation Factor 4E (EIF4E) (C-Term) Peptide
EIF4E
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all EIF4E products
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF4E antibody (Catalog #: ARP40377_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Synonyms
- AUTS19 Peptide, CBP Peptide, EIF4E1 Peptide, EIF4EL1 Peptide, EIF4F Peptide, eif4e-1 Peptide, zgc:86680 Peptide, EG668879 Peptide, Eif4e-ps Peptide, If4e Peptide, eIF-4E Peptide, 0260/09 Peptide, 0587/11 Peptide, 0589/11 Peptide, 0919/12 Peptide, 1004/13 Peptide, 2 Peptide, 7238 Peptide, CG4035 Peptide, CT13384 Peptide, CT39424 Peptide, CT39426 Peptide, D-eIF4E Peptide, Dmel\\CG4035 Peptide, Eif4E Peptide, Eif4e Peptide, IF4E Peptide, dEif4e Peptide, deIF-4E Peptide, deIF4E Peptide, eIF 4E Peptide, eIF-4E1 Peptide, eIF-4E2 Peptide, eIF-4EII Peptide, eIF-4e Peptide, eIF4E Peptide, eIF4E-1 Peptide, eIF4E-1/2 Peptide, eIF4E-2 Peptide, eIF4E1 Peptide, eIF4EI Peptide, eIF4e Peptide, eif-4E Peptide, eif-4e Peptide, eif4e Peptide, l(3)07238 Peptide, l(3)67Af Peptide, l(3)S025007 Peptide, l(3)S026009 Peptide, l(3)S058711 Peptide, l(3)S091912 Peptide, cbp Peptide, eif4f Peptide, eif4e1 Peptide, eif4el1 Peptide, EIF-4E Peptide, zgc:101581 Peptide, eukaryotic translation initiation factor 4E Peptide, eukaryotic translation initiation factor 4ea Peptide, Eukaryotic initiation factor 4E Peptide, eucaryotic initiation factor 6 Peptide, eukaryotic translation initiation factor 4E L homeolog Peptide, eukaryotic translation initiation factor 4E family member 1B S homeolog Peptide, translation initiation factor eIF4E Peptide, eukaryotic translation initiation factor 4eb Peptide, EIF4E Peptide, eif4ea Peptide, Eif4e Peptide, eIF-4E Peptide, eif6 Peptide, eif4e Peptide, eif4e.L Peptide, eif4e1b.S Peptide, LOC100533326 Peptide, eif4eb Peptide
- Background
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All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP, EIF4E1, EIF4EL1, EIF4F, MGC111573
Protein Interaction Partner: EIF4EBP1,EIF4G1,EIF4G1,EIF4G1,MKNK1,EIF4B,EIF4E,EIF4EBP1,EIF4EBP2,EIF4EBP3,EIF4ENIF1,EIF4G1,EIF4G2,EIF4G3,EMX2,MAPKAPK5,MKNK1,MKNK2,PML,PRKCA,PRKCB,PRKCG,EIF3B,EIF3F,EIF4A1,EIF4A2,EIF4E,EIF4EBP1,EIF4EBP2,EIF4EBP3,EIF4ENIF1,EIF4G1,EIF4G2,MKNK1,PML
Protein Size: 217 - Molecular Weight
- 25 kDa
- Gene ID
- 1977
- NCBI Accession
- NM_001968, NP_001959
- UniProt
- P06730
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