Eukaryotic Translation Initiation Factor 4E (EIF4E) (Middle Region) Peptide
EIF4E
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EIF4E products
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FKDGIEPMWE DEKNKRGGRW LITLNKQQRR SDLDRFWLET LLCLIGESFD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- EIF4E Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Synonyms
- AUTS19 Peptide, CBP Peptide, EIF4E1 Peptide, EIF4EL1 Peptide, EIF4F Peptide, eif4e-1 Peptide, zgc:86680 Peptide, EG668879 Peptide, Eif4e-ps Peptide, If4e Peptide, eIF-4E Peptide, 0260/09 Peptide, 0587/11 Peptide, 0589/11 Peptide, 0919/12 Peptide, 1004/13 Peptide, 2 Peptide, 7238 Peptide, CG4035 Peptide, CT13384 Peptide, CT39424 Peptide, CT39426 Peptide, D-eIF4E Peptide, Dmel\\CG4035 Peptide, Eif4E Peptide, Eif4e Peptide, IF4E Peptide, dEif4e Peptide, deIF-4E Peptide, deIF4E Peptide, eIF 4E Peptide, eIF-4E1 Peptide, eIF-4E2 Peptide, eIF-4EII Peptide, eIF-4e Peptide, eIF4E Peptide, eIF4E-1 Peptide, eIF4E-1/2 Peptide, eIF4E-2 Peptide, eIF4E1 Peptide, eIF4EI Peptide, eIF4e Peptide, eif-4E Peptide, eif-4e Peptide, eif4e Peptide, l(3)07238 Peptide, l(3)67Af Peptide, l(3)S025007 Peptide, l(3)S026009 Peptide, l(3)S058711 Peptide, l(3)S091912 Peptide, cbp Peptide, eif4f Peptide, eif4e1 Peptide, eif4el1 Peptide, EIF-4E Peptide, zgc:101581 Peptide, eukaryotic translation initiation factor 4E Peptide, eukaryotic translation initiation factor 4ea Peptide, Eukaryotic initiation factor 4E Peptide, eucaryotic initiation factor 6 Peptide, eukaryotic translation initiation factor 4E L homeolog Peptide, eukaryotic translation initiation factor 4E family member 1B S homeolog Peptide, translation initiation factor eIF4E Peptide, eukaryotic translation initiation factor 4eb Peptide, EIF4E Peptide, eif4ea Peptide, Eif4e Peptide, eIF-4E Peptide, eif6 Peptide, eif4e Peptide, eif4e.L Peptide, eif4e1b.S Peptide, LOC100533326 Peptide, eif4eb Peptide
- Background
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The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Alias Symbols: CBP, EIF4F, AUTS19, EIF4E1, eIF-4E, EIF4EL1
Protein Size: 217 - Gene ID
- 1977
- NCBI Accession
- NM_001130678, NP_001124150
- UniProt
- P06730
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